iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-063079

Ensembl Protein ID

ENSMODP00000006974.2

UniProt Accession

F7CF07; F7CF07_MONDO

Protein Name

Uncharacterized protein

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000005628.3	ENSMODT00000007114.2	ENSMODP00000006974.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	3.80e-30	104.4	9	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 3    eeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL...vqkegWfrefl 73
            +++ l++++++r+++++ v++vld yl+ fl  e ke i ++a+t+gn+ aae LL+tL    +  gW +efl
   Q: 9    KNFLNLIQCFRPRLKQYIRVEPVLD-YLT-FLDREKKEHIRQTAATQGNAVAAEFLLSTLekgTWGPGWAQEFL 80
           68999********************.***.******************************************96 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSFESSQEKN FLNLIQCFRP RLKQYIRVEP VLDYLTFLDR EKKEHIRQTA ATQGNAVAAE 60
FLLSTLEKGT WGPGWAQEFL TGLNHGGCTL AARYMNPDLA DLPSPSLETC YDQCVQLLDI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTGAACAC AATGATAGAA CTGAACGGAC TCTAAGATTA TTTAAATCCA ACTTTCTTTT 60
TATAGAGGAG AAAAATAAGG TCGTATTAGC CAGTTTCTCT CTGAAACCGA AGCTGAAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

KEGG

mdo:100022390

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	68.35	0.00e+00	1334.00
IUUC-Apl-003900	Anas platyrhynchos	61.11	0.00e+00	1204.00
IUUC-Aca-005329	Anolis carolinensis	57.94	0.00e+00	1020.00
IUUC-Ame-011305	Astyanax mexicanus	54.74	0.00e+00	755.00
IUUC-Bta-012361	Bos taurus	71.05	0.00e+00	1338.00
IUUC-Cel-018230	Caenorhabditis elegans	27.36	2.00e-60	227.00
IUUC-Cja-018760	Callithrix jacchus	69.78	0.00e+00	1276.00
IUUC-Cfa-020321	Canis familiaris	69.10	0.00e+00	1293.00
IUUC-Cpo-022450	Cavia porcellus	67.45	0.00e+00	1305.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	31.71	4.00e-14	73.90
IUUC-Csa-024194	Chlorocebus sabaeus	72.18	0.00e+00	1285.00
IUUC-Cho-024364	Choloepus hoffmanni	63.11	0.00e+00	848.00
IUUC-Cin-025792	Ciona intestinalis	29.62	6.00e-73	268.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	34.71	3.00e-14	75.10
IUUC-Dre-028305	Danio rerio	46.02	0.00e+00	766.00
IUUC-Dno-029831	Dasypus novemcinctus	70.01	0.00e+00	1323.00
IUUC-Dor-030410	Dipodomys ordii	75.04	0.00e+00	922.00
IUUC-Ete-032950	Echinops telfairi	67.21	8.00e-165	574.00
IUUC-Eca-034279	Equus caballus	71.93	0.00e+00	1344.00
IUUC-Eeu-034678	Erinaceus europaeus	67.84	0.00e+00	1339.00
IUUC-Fca-035618	Felis catus	73.68	0.00e+00	828.00
IUUC-Fal-037106	Ficedula albicollis	67.79	0.00e+00	967.00
IUUC-Fso-038398	Fusarium solani	26.27	1.00e-30	129.00
IUUC-Gmo-038598	Gadus morhua	50.21	0.00e+00	677.00
IUUC-Gga-040467	Gallus gallus	60.61	0.00e+00	1180.00
IUUC-Gac-042316	Gasterosteus aculeatus	46.68	0.00e+00	823.00
IUUC-Ggo-045461	Gorilla gorilla	71.11	0.00e+00	1281.00
IUUC-Hsa-045771	Homo sapiens	71.50	0.00e+00	1276.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	71.69	0.00e+00	1350.00
IUUC-Lch-049913	Latimeria chalumnae	65.39	0.00e+00	934.00
IUUC-Loc-052768	Lepisosteus oculatus	52.01	0.00e+00	969.00
IUUC-Laf-053933	Loxodonta africana	70.66	0.00e+00	1299.00
IUUC-Mcc-054695	Macaca mulatta	72.28	0.00e+00	1291.00
IUUC-Meu-056829	Macropus eugenii	77.57	0.00e+00	1204.00
IUUC-Mga-059205	Meleagris gallopavo	60.33	0.00e+00	1177.00
IUUC-Mvi-060497	Microbotryum violaceum	34.87	1.00e-17	86.30
IUUC-Mmr-060703	Microcebus murinus	71.44	0.00e+00	1310.00
IUUC-Mmu-064066	Mus musculus	68.39	0.00e+00	1361.00
IUUC-Mpu-066261	Mustela putorius furo	69.26	0.00e+00	1310.00
IUUC-Mlu-068196	Myotis lucifugus	70.28	0.00e+00	1300.00
IUUC-Nfi-068405	Neosartorya fischeri	24.53	2.00e-25	111.00
IUUC-Nle-069479	Nomascus leucogenys	72.29	0.00e+00	1294.00
IUUC-Opr-070717	Ochotona princeps	63.53	0.00e+00	945.00
IUUC-Ont-071702	Oreochromis niloticus	47.70	0.00e+00	868.00
IUUC-Oan-073639	Ornithorhynchus anatinus	64.91	0.00e+00	1177.00
IUUC-Ocu-074521	Oryctolagus cuniculus	70.63	0.00e+00	1342.00
IUUC-Ola-086351	Oryzias latipes	45.73	0.00e+00	798.00
IUUC-Oga-088539	Otolemur garnettii	69.52	0.00e+00	1313.00
IUUC-Oar-090186	Ovis aries	71.08	0.00e+00	1305.00
IUUC-Ptr-090575	Pan troglodytes	71.80	0.00e+00	1283.00
IUUC-Pan-092371	Papio anubis	72.47	0.00e+00	1293.00
IUUC-Psi-093072	Pelodiscus sinensis	62.71	0.00e+00	1254.00
IUUC-Pma-094345	Petromyzon marinus	43.62	4.00e-97	348.00
IUUC-Pfo-096401	Poecilia formosa	47.19	0.00e+00	786.00
IUUC-Pab-097623	Pongo abelii	71.21	0.00e+00	1284.00
IUUC-Pca-100993	Procavia capensis	63.64	0.00e+00	1041.00
IUUC-Pva-102227	Pteropus vampyrus	66.37	0.00e+00	1200.00
IUUC-Pgr-103529	Puccinia graminis	38.21	3.00e-16	81.30
IUUC-Rno-105198	Rattus norvegicus	68.57	0.00e+00	1361.00
IUUC-Sha-107622	Sarcophilus harrisii	82.42	0.00e+00	1632.00
IUUC-Sar-113625	Sorex araneus	76.13	2.00e-144	506.00
IUUC-Ssc-116120	Sus scrofa	32.05	2.00e-80	294.00
IUUC-Tgu-117486	Taeniopygia guttata	57.96	0.00e+00	1121.00
IUUC-Tru-118445	Takifugu rubripes	45.86	0.00e+00	811.00
IUUC-Tsy-119512	Tarsius syrichta	69.46	0.00e+00	1254.00
IUUC-Tni-120711	Tetraodon nigroviridis	44.64	0.00e+00	848.00
IUUC-Tre-122194	Trichoderma reesei	23.25	9.00e-18	86.70
IUUC-Tbe-127644	Tupaia belangeri	63.25	0.00e+00	1157.00
IUUC-Ttr-128989	Tursiops truncatus	66.37	0.00e+00	1287.00
IUUC-Vpa-130587	Vicugna pacos	67.59	0.00e+00	1046.00
IUUC-Xtr-132127	Xenopus tropicalis	52.15	0.00e+00	1015.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence