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Tag Content
UUCD2 ID IUUC-Oga-088618
UUCD1 version UUC-OtG-00806
Ensembl Protein ID ENSOGAP00000003853.2
UniProt Accession H0WPM5; H0WPM5_OTOGA
Genbank Protein ID ENSOGAP00000003853
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAQR03115874
Gene Name USP28
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOGAG00000004313.2 ENSOGAT00000004319.2 ENSOGAP00000003853.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 6.50e-59 199.8 143 629
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeef 84
           +GlkN+gNtC++ +v+Q+L+++pe+r+l+l+     +  e+++    ++++  ++++lq lf+ ++ s++k v+p++ l+ lk + ++ 
   Q: 143  VGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSynlpqNVLENCQSH-TDKRNIMFMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRS- 229
           6******************************97665555555544.478888*******************************99987. PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
           s+ +qqD++Ef++ lld le++++                     + +++ +k+++++++lF g++ ++ + +        +e+f +++
   Q: 230  SEEQQQDVSEFTHKLLDWLEDAFQL------------------AVNVNNPRNKSENPMVQLFYGTFLTEGVREGKPFC--NNETFGQYP 298
           99*********************22..................23457899****************99998665555..5899***** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           l+v+g +     +l++cLe  + e  +e    +  +   ++++  ++ +++klP+vL+++L+Rf+f+++ +++eki++k+efp+ + ++
   Q: 299  LQVNGYR-----NLDECLEGAMVEGDIE----LLPSD--HSVKYGQERWFTKLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMD 376
           *******.....99****7766666665....55544..456778899***************************************** PP
   S: 263  pfcts.................................................................................... 267
           +++++                                                                                    
   Q: 377  RYMHRskeiirnkrehirklkeeikvlqekleryvkygsgparfplpdmlkyviefastkpasescpperdtcltlplspghcpvsdlt 465
           *****777777777777777777777777777777777777777777777777766666666666666666666666666666666665 PP
   S: 268  ....peekqke.............................................................................. 274
               +     +                                                                              
   Q: 466  seesT-----Ntdsssqdgestfsspgdslhkskpllssrsslempahpaprkvtdeeinfvktclqrwrseieqdiqdlknciasttq 549
           55550.....0555556666777777777777777777777888888888888888888888888888999999999999999999999 PP
   S: 275  ............kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                       ++ Y+L+av+vH+G+++ GHY+ay++n+ ++ Wl+++D +Vte+++ee ++++       +aY+l+Y 
   Q: 550  aieqmycdpllcQVPYRLHAVLVHEGQANAGHYWAYIYNQPRQtWLKYNDISVTESSWEELERDSYgglrnVSAYCLMYI 629
           999********9***************************88888*******************8879************6 PP
   
Organism Otolemur garnettii
Protein Sequence
(Fasta)
SCQMLLNQLK EITGIQDPSF LHEALKASNG DITQAVSLLT DERVKEPSQD TVATEPSEVE 60
GSAATQEVLA KVIDLTHDNK DDLQAAIALS LLESPKIQAD GRDLHRMHEP TSVETKRSKR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oga-088618|DUB,USP|Otolemur garnettii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TAGAGCTGCC AAATGCTGTT AAATCAACTG AAAGAAATCA CAGGCATTCA GGACCCCTCC 60
TTTCTTCACG AAGCTCTGAA GGTGGGTTTT CAGACCCTTA TTAGTCATCA GGCTTTAAAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oga-088618|DUB,USP|Otolemur garnettii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:0016604--C:nuclear body
GO:0043234--C:protein complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008283--P:cell proliferation
GO:0034644--P:cellular response to UV
GO:0000077--P:DNA damage checkpoint
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0016579--P:protein deubiquitination
GO:0007265--P:Ras protein signal transduction
GO:0031647--P:regulation of protein stability
GO:0010212--P:response to ionizing radiation
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001836 Ailuropoda melanoleuca 92.85 0.00e+00 2002.00
IUUC-Apl-004010 Anas platyrhynchos 69.07 0.00e+00 1468.00
IUUC-Aca-004741 Anolis carolinensis 58.83 0.00e+00 840.00
IUUC-Acl-008164 Aspergillus clavatus 24.15 3.00e-15 78.20
IUUC-Ang-009577 Aspergillus niger 36.36 7.00e-11 63.50
IUUC-Bta-013377 Bos taurus 91.44 0.00e+00 1900.00
IUUC-Cja-019977 Callithrix jacchus 94.71 0.00e+00 2001.00
IUUC-Cfa-020378 Canis familiaris 89.32 0.00e+00 1332.00
IUUC-Cpo-021817 Cavia porcellus 89.00 0.00e+00 1906.00
IUUC-Csa-023446 Chlorocebus sabaeus 93.07 0.00e+00 1383.00
IUUC-Cho-024717 Choloepus hoffmanni 83.46 0.00e+00 1220.00
IUUC-Cme-027167 Cyanidioschyzon merolae 30.96 8.00e-15 76.30
IUUC-Dre-028105 Danio rerio 57.19 0.00e+00 722.00
IUUC-Dno-029559 Dasypus novemcinctus 89.87 0.00e+00 1491.00
IUUC-Dor-030955 Dipodomys ordii 89.25 0.00e+00 1906.00
IUUC-Ete-032828 Echinops telfairi 80.65 0.00e+00 1152.00
IUUC-Eca-034300 Equus caballus 92.18 0.00e+00 1907.00
IUUC-Eeu-034458 Erinaceus europaeus 87.71 0.00e+00 1703.00
IUUC-Fca-035753 Felis catus 92.00 0.00e+00 1984.00
IUUC-Fal-037062 Ficedula albicollis 63.18 0.00e+00 875.00
IUUC-Gmo-039593 Gadus morhua 52.47 0.00e+00 1038.00
IUUC-Gga-040878 Gallus gallus 64.80 0.00e+00 1312.00
IUUC-Gac-041867 Gasterosteus aculeatus 54.24 0.00e+00 1123.00
IUUC-Ggo-045384 Gorilla gorilla 94.71 0.00e+00 2002.00
IUUC-Hsa-046277 Homo sapiens 94.80 0.00e+00 2006.00
IUUC-Itr-048276 Ictidomys tridecemlineatus 86.57 0.00e+00 1158.00
IUUC-Lch-049692 Latimeria chalumnae 66.60 0.00e+00 1399.00
IUUC-Laf-053808 Loxodonta africana 86.74 0.00e+00 1811.00
IUUC-Mcc-055473 Macaca mulatta 93.33 0.00e+00 1386.00
IUUC-Meu-056416 Macropus eugenii 73.68 0.00e+00 1499.00
IUUC-Mga-060011 Meleagris gallopavo 67.20 0.00e+00 1398.00
IUUC-Mmr-060720 Microcebus murinus 93.19 0.00e+00 1919.00
IUUC-Mdo-061955 Monodelphis domestica 77.36 0.00e+00 1637.00
IUUC-Mmu-063870 Mus musculus 86.00 0.00e+00 1832.00
IUUC-Mpu-066454 Mustela putorius furo 88.80 0.00e+00 1295.00
IUUC-Mlu-067487 Myotis lucifugus 87.41 0.00e+00 1850.00
IUUC-Nle-070044 Nomascus leucogenys 94.90 0.00e+00 2013.00
IUUC-Opr-070888 Ochotona princeps 98.19 1.00e-161 564.00
IUUC-Ont-072386 Oreochromis niloticus 55.40 0.00e+00 743.00
IUUC-Ocu-074523 Oryctolagus cuniculus 90.21 0.00e+00 1909.00
IUUC-Ola-086393 Oryzias latipes 55.19 0.00e+00 1117.00
IUUC-Oar-089848 Ovis aries 83.24 0.00e+00 1807.00
IUUC-Ptr-091630 Pan troglodytes 94.66 0.00e+00 1533.00
IUUC-Psi-093422 Pelodiscus sinensis 64.20 0.00e+00 1371.00
IUUC-Pma-094250 Petromyzon marinus 52.27 5.00e-73 267.00
IUUC-Pfo-096466 Poecilia formosa 57.59 0.00e+00 762.00
IUUC-Pab-098337 Pongo abelii 94.80 0.00e+00 2007.00
IUUC-Pca-100901 Procavia capensis 76.63 0.00e+00 1558.00
IUUC-Pva-102226 Pteropus vampyrus 86.79 0.00e+00 1709.00
IUUC-Rno-105735 Rattus norvegicus 82.56 0.00e+00 1837.00
IUUC-Sha-107489 Sarcophilus harrisii 85.83 0.00e+00 1843.00
IUUC-Ssl-108532 Sclerotinia sclerotiorum 34.57 3.00e-09 58.20
IUUC-Tgu-116609 Taeniopygia guttata 68.24 0.00e+00 1406.00
IUUC-Tsy-118971 Tarsius syrichta 87.72 0.00e+00 1251.00
IUUC-Tni-119983 Tetraodon nigroviridis 55.51 0.00e+00 1120.00
IUUC-Ttr-128887 Tursiops truncatus 86.83 0.00e+00 1792.00
IUUC-Vpa-130614 Vicugna pacos 91.29 0.00e+00 1486.00
IUUC-Xtr-132436 Xenopus tropicalis 62.79 0.00e+00 1291.00
Created Date 25-Jun-2017

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