iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000006040.1	ENSSHAT00000007011.1	ENSSHAP00000006949.1
ENSSHAG00000006040.1	ENSSHAT00000007012.1	ENSSHAP00000006950.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	3.10e-11	42.8	351	376
ULD/UDP/UBQ/UBQ_Other	1.80e-12	47.1	225	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 4    qWaCsaCTflNePeavkCemCsrpRg 29
           +W+C++CTf+N P +++CemCs+ ++
   Q: 351  GWSCPSCTFINVPGRPGCEMCSTEQP 376
           7*********************9876 PP

ULD/UDP/UBQ/UBQ_Other

   S: 1    vqvtvksldgs.eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglk.dg 64
           vqvtv+++ +s + +l+v+p++t+a L+e+++k+ g+pp+ qr+++ G++L  + ++La+yg++ dg
   Q: 225  VQVTVEDAASSaHISLRVHPHSTIAALQEQVFKEYGFPPRVQRWVI-GRCLcVPERSLASYGVQrDG 290
           79********************************************.**************885155 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

XXXXXXXXXX XXXXXXXXXX ASLEETAVLV EVRGLGPESG PGPGPGPDGL WRLQLSAEAS 60
RPGHFRLVLQ GSGSPPGEGF QWSLESVACT SRGPRELELQ PPQEGPGPGV LTLCFCDPQD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCAGGCCTC CTTTCAATGG TACAGCCTGC CCTGCCCCCC CATCAGCGTA ATTGGTAGAG 60
TCCTCCAGCT CCCACCCCTG CGGATCAGTG GTAGGATCCT CCCTGCTTCC CCCCCCCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR031912--Sharpin_PH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR001876--Znf_RanBP2

PROSITE

PS50053--UBIQUITIN_2
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF16764--Sharpin_PH

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0005829--C:cytosol
GO:0071797--C:LUBAC complex
GO:0008270--F:zinc ion binding
GO:0030262--P:apoptotic nuclear changes
GO:0031424--P:keratinization
GO:0007005--P:mitochondrion organization
GO:0050728--P:negative regulation of inflammatory response
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0097039--P:protein linear polyubiquitination
GO:2000348--P:regulation of CD40 signaling pathway
GO:0010803--P:regulation of tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001223	Ailuropoda melanoleuca	54.65	6.00e-78	283.00
IUUC-Apl-004151	Anas platyrhynchos	67.39	2.00e-17	79.70
IUUC-Acl-008308	Aspergillus clavatus	36.17	2.70e-01	29.60
IUUC-Bta-012948	Bos taurus	54.17	2.00e-83	302.00
IUUC-Cja-019031	Callithrix jacchus	53.24	4.00e-66	244.00
IUUC-Cfa-020863	Canis familiaris	53.03	3.00e-71	261.00
IUUC-Cpo-022499	Cavia porcellus	50.85	6.00e-72	264.00
IUUC-Csa-023641	Chlorocebus sabaeus	52.44	2.00e-66	245.00
IUUC-Dno-029459	Dasypus novemcinctus	60.48	9.00e-43	166.00
IUUC-Dor-030914	Dipodomys ordii	47.23	2.00e-48	186.00
IUUC-Ete-032940	Echinops telfairi	54.82	8.00e-60	224.00
IUUC-Eca-033537	Equus caballus	53.67	3.00e-83	301.00
IUUC-Eeu-035176	Erinaceus europaeus	59.41	1.00e-44	173.00
IUUC-Fca-035971	Felis catus	52.55	3.00e-80	291.00
IUUC-Gmo-039219	Gadus morhua	35.48	4.00e-41	161.00
IUUC-Ggo-044678	Gorilla gorilla	51.40	7.00e-67	247.00
IUUC-Hsa-046578	Homo sapiens	52.69	1.00e-68	253.00
IUUC-Itr-047913	Ictidomys tridecemlineatus	51.93	3.00e-74	272.00
IUUC-Mcc-055686	Macaca mulatta	51.75	3.00e-70	258.00
IUUC-Meu-055912	Macropus eugenii	74.29	6.00e-95	340.00
IUUC-Mor-057018	Magnaporthe oryzae	44.19	3.00e-06	46.20
IUUC-Mmr-060584	Microcebus murinus	51.45	2.00e-69	255.00
IUUC-Mdo-062191	Monodelphis domestica	81.02	8.00e-148	516.00
IUUC-Mmu-063740	Mus musculus	49.56	2.00e-63	235.00
IUUC-Mpu-066878	Mustela putorius furo	55.24	2.00e-69	256.00
IUUC-Mlu-067878	Myotis lucifugus	54.86	6.00e-79	287.00
IUUC-Nle-069748	Nomascus leucogenys	54.63	1.00e-65	243.00
IUUC-Ont-072270	Oreochromis niloticus	38.05	1.00e-38	153.00
IUUC-Obr-076087	Oryza brachyantha	42.50	2.00e-03	35.80
IUUC-Oga-088300	Otolemur garnettii	52.14	4.00e-75	274.00
IUUC-Oar-089549	Ovis aries	54.42	8.00e-85	306.00
IUUC-Ptr-090961	Pan troglodytes	53.51	4.00e-64	238.00
IUUC-Pan-092687	Papio anubis	52.87	5.00e-68	251.00
IUUC-Pfo-096865	Poecilia formosa	40.80	8.00e-36	144.00
IUUC-Pab-097872	Pongo abelii	53.51	1.00e-61	229.00
IUUC-Pca-100363	Procavia capensis	60.78	6.00e-54	204.00
IUUC-Pva-102595	Pteropus vampyrus	54.49	6.00e-69	254.00
IUUC-Rno-105856	Rattus norvegicus	46.96	2.00e-59	222.00
IUUC-Ssl-108588	Sclerotinia sclerotiorum	39.53	2.70e-02	33.10
IUUC-Sar-113611	Sorex araneus	81.13	4.00e-19	88.60
IUUC-Ssc-116263	Sus scrofa	55.28	3.00e-80	291.00
IUUC-Tni-120004	Tetraodon nigroviridis	39.18	2.00e-41	162.00
IUUC-Tbe-127471	Tupaia belangeri	54.79	2.00e-57	216.00
IUUC-Ttr-128534	Tursiops truncatus	56.51	1.00e-63	236.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence