iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121670

Ensembl Protein ID

EOY08524

UniProt Accession

A0A061F1X6; A0A061F1X6_THECC

Genbank Protein ID

EOY08524.1

Protein Name

Ubiquitin-specific protease 8 isoform 1

Genbank Nucleotide ID

CM001883

Gene Name

TCM_023086

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_023086	EOY08524	EOY08524
TCM_023086	EOY08526	EOY08526
TCM_023086	EOY08525	EOY08525

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.70e-106	356.5	344	939

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflld 101
           tGl+NlgNtC+mNS++QcL+++p+l +++l  +++++n +np +++gel+ ++ +l+++lw      v+pr+++ +l+k+a++fsgy+q+D+qEflaflld
   Q: 344  TGLQNLGNTCFMNSAIQCLVHTPQLVDYFLGDYQKDINYKNPLGMNGELALAFGELLRKLWAPGAVPVAPRMFKCKLAKFAPQFSGYNQHDSQEFLAFLLD 444
           7**************************************************************************************************** PP
   S: 102  qleeelkkeknkpkeeeeeed...kselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.............. 185
           +l+e+l++ k kp+ e+++++   ++e  de ++++  +n+s+i+d+ qgq++s+++c+ c++vs++++pf++++lp+p+ + + ++              
   Q: 445  GLHEDLNRVKCKPYIEAKDAEgcpDEEVADEYWRNHLARNDSIIVDVCQGQYRSTLVCPVCKKVSVTFDPFMYVTLPLPSTTMRTMTltvfstdgimlptp 545
           ********99999988877762225667777**************************************************9887779************* PP
   S: 186  ..................................................................................................... 185
                                                                                                                
   Q: 546  ftiavpkcgrlkdlidtlsvacslrndetllvaeiyknqifrlldepsdslalirdddklvayrlpkvsetyplvvflhqqversysfgvvasnwkpfgvp 646
           ***************************************************************************************************** PP
   S: 186  ..................................................................................................... 185
                                                                                                                
   Q: 647  lvariqdlssgseirnqflkllcpflmpvedvvndydgnetgntvnenskmedivsplvsdsdvgsdsgaendfrlntdfkfylinklepleikmnkpvsi 747
           ***************************************************************************************************** PP
   S: 186  ..............................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfs 240
                                                         sl++cLe f +ee l  ++++yc++ckk ++a+kkl+l++lPe+L++hLkRfs++
   Q: 748  srftkkfdvsvhwsekmmekydtcllsslpevfkpqlftrrpqesiSLNKCLEGFLQEEPLGPDDMWYCPRCKKPRQANKKLDLWRLPEILVIHLKRFSYN 848
           **************************************************************************************************886 PP
   S: 241  eeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           +   +++k+++ v+fp++ L+ls++ ++ +++   ++ Y+L+a+ +H+G++++GHY+a+v + + +W++fdD+kV +v+e+++++   s aYvlfY+r
   Q: 849  R--FFKNKLETFVDFPIHdLNLSNYISHIDSQL--SNCYQLYAISNHYGGMGGGHYTAFVDHGHSRWFEFDDDKVFAVSEDRIKS---SAAYVLFYRR 939
           6..799**********************99888..99************************************************...********98 PP

Organism

Theobroma cacao

Protein Sequence
(Fasta)

MNGLAEKLNF SIIIAKTTTR LLSVKVANLS IPAVRLFKAV LSKALRALFF FSMDDSFSSE 60
DDDHLFDLDY HPYARKRPLS SRLDRDEHDE TDDEETNRQK LYLVPYRWWK ETQRSVADQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAAATTAAA ATTTTTTATT TTAATCTTTG CAAAAATCAA AACAGTACAA AATGTCTAGG 60
GAGTGAACAT CCATTTAAGA GAAGCGGATT GCAAGCGCCG TTGTGCCACG TGTCAAGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-010757	Astyanax mexicanus	40.06	2.00e-120	426.00
IUUC-Bta-013128	Bos taurus	38.96	4.00e-116	412.00
IUUC-Gmo-038866	Gadus morhua	40.96	2.00e-110	393.00
IUUC-Gma-043368	Glycine max	59.01	0.00e+00	936.00
IUUC-Loc-052105	Lepisosteus oculatus	39.14	2.00e-113	402.00
IUUC-Mtr-057661	Medicago truncatula	56.62	0.00e+00	890.00
IUUC-Ont-071834	Oreochromis niloticus	40.00	2.00e-112	400.00
IUUC-Oga-089022	Otolemur garnettii	38.74	4.00e-116	411.00
IUUC-Oar-089767	Ovis aries	38.96	8.00e-116	410.00
IUUC-Pfo-097110	Poecilia formosa	39.69	3.00e-118	419.00
IUUC-Pop-099191	Populus trichocarpa	64.95	0.00e+00	866.00
IUUC-Ppe-101637	Prunus persica	66.06	0.00e+00	841.00
IUUC-Pva-102394	Pteropus vampyrus	38.13	3.00e-110	392.00
IUUC-Sce-106170	Saccharomyces cerevisiae	39.22	3.00e-56	213.00
IUUC-Tru-118298	Takifugu rubripes	40.09	5.00e-117	414.00
IUUC-Tni-120093	Tetraodon nigroviridis	39.63	3.00e-116	412.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence