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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-045712
Ensembl Protein ID ENSP00000344871.6
UniProt Accession O00160; Q8WWN7; MYO1F_HUMAN
Genbank Protein ID CAC83948.1; BAC03995.1; AAH28071.1; CAA67058.1
Protein Name Unconventional myosin-If; Myosin-Ie
Genbank Nucleotide ID AJ310570; AK092877; AC092298; X98411
Gene Name MYO1F
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000142347.16 ENST00000338257.12 ENSP00000344871.6
ENSG00000142347.16 ENST00000598005.1 ENSP00000469098.1
ENSG00000142347.16 ENST00000598321.5 ENSP00000469387.1
ENSG00000142347.16 ENST00000596675.1 ENSP00000469668.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbcircBasecircRNADbCircNet
miRTarBasemicroRNATRANSFACTargetScan
RepTarmiRNAMapmiRcodeRAID2
Protein-protein Interaction
IIDPINAHINTInWeb_IM
Disease-associated Variation
ClinVarGWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDUniProtPHOSIDABioGRID
mUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 8.50e-13 49.7 1045 1098
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           ++++ly+y +q+ deL+++  +v++++   e   gW+kg   l+g++GlfP n+vek+
   Q: 1045 RCRALYQYVGQDVDELSFNVNEVIEIL--MEDPSGWWKG--RLHGQEGLFPGNYVEKI 1098
           699************************..88899*****..9*************996 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).
 Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).
Protein Sequence
(Fasta)
MGSKERFHWQ SHNVKQSGVD DMVLLPQITE DAIAANLRKR FMDDYIFTYI GSVLISVNPF 60
KQMPYFTDRE IDLYQGAAQY ENPPHIYALT DNMYRNMLID CENQCVIISG ESGAGKTVAA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-045712|UBD,SH3|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATCAAGTTCT GACCCCTCCC TTCAGGCTCA GAGCCCCAAA CAGCCAGCTC CCCGCCCCCC 60
TCCACACCCA GCTTCCCTCC CCCATGGCCT CGGCCCCTCC CGCCAAAGGA AGTGAGAAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-045712|UBD,SH3|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0009--Actin-binding
KW-0067--ATP-binding
KW-0112--Calmodulin-binding
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0518--Myosin
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0728--SH3 domain
Interpro

IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom
IPR001609--Myosin_head_motor_dom
IPR010926--Myosin_TH1
IPR027417--P-loop_NTPase
IPR001452--SH3_domain
PROSITE

PS50096--IQ
PS51456--MYOSIN_MOTOR
PS50002--SH3
PS51757--TH1
Pfam

PF00063--Myosin_head
PF06017--Myosin_TH1
PF14604--SH3_9
PRINTS

PR00193--MYOSINHEAVY
PR00452--SH3DOMAIN
SMART

SM00242--MYSc
SM00326--SH3
Gene Ontology

GO:0016461--C:unconventional myosin complex
GO:0003779--F:actin binding
GO:0005524--F:ATP binding
GO:0003774--F:motor activity
KEGG hsa:4542
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002158 Ailuropoda melanoleuca 94.62 0.00e+00 2081.00
IUUC-Apl-003803 Anas platyrhynchos 81.34 0.00e+00 1811.00
IUUC-Ago-007771 Ashbya gossypii 56.86 5.00e-12 65.50
IUUC-Acl-008168 Aspergillus clavatus 43.62 0.00e+00 748.00
IUUC-Afl-008552 Aspergillus flavus 45.31 0.00e+00 751.00
IUUC-Afu-008958 Aspergillus fumigatus 45.19 0.00e+00 722.00
IUUC-Ang-009818 Aspergillus niger 43.72 0.00e+00 754.00
IUUC-Aor-009891 Aspergillus oryzae 45.31 0.00e+00 751.00
IUUC-Ate-010325 Aspergillus terreus 43.81 0.00e+00 749.00
IUUC-Ame-011335 Astyanax mexicanus 77.04 0.00e+00 1743.00
IUUC-Bta-012409 Bos taurus 95.17 0.00e+00 2093.00
IUUC-Cel-018582 Caenorhabditis elegans 55.26 0.00e+00 1186.00
IUUC-Cfa-020409 Canis familiaris 92.53 0.00e+00 2057.00
IUUC-Cpo-021332 Cavia porcellus 92.03 0.00e+00 2103.00
IUUC-Dre-027687 Danio rerio 76.13 0.00e+00 1724.00
IUUC-Eca-033919 Equus caballus 81.29 0.00e+00 1677.00
IUUC-Fca-036174 Felis catus 88.73 0.00e+00 1887.00
IUUC-Fal-037393 Ficedula albicollis 82.84 0.00e+00 1815.00
IUUC-Gga-040323 Gallus gallus 82.99 0.00e+00 1838.00
IUUC-Ggo-045277 Gorilla gorilla 97.44 0.00e+00 2097.00
IUUC-Itr-048108 Ictidomys tridecemlineatus 93.21 0.00e+00 2056.00
IUUC-Loc-052303 Lepisosteus oculatus 78.83 0.00e+00 1758.00
IUUC-Laf-054277 Loxodonta africana 79.42 0.00e+00 1622.00
IUUC-Mcc-054773 Macaca mulatta 98.28 0.00e+00 2181.00
IUUC-Mmr-061357 Microcebus murinus 94.90 0.00e+00 2115.00
IUUC-Mdo-062467 Monodelphis domestica 87.88 0.00e+00 1989.00
IUUC-Mmu-063711 Mus musculus 93.72 0.00e+00 2076.00
IUUC-Mpu-066658 Mustela putorius furo 94.90 0.00e+00 2098.00
IUUC-Nfi-068411 Neosartorya fischeri 45.67 0.00e+00 720.00
IUUC-Ont-072236 Oreochromis niloticus 77.09 0.00e+00 1718.00
IUUC-Oan-073284 Ornithorhynchus anatinus 79.64 6.00e-179 620.00
IUUC-Ocu-074538 Oryctolagus cuniculus 94.62 0.00e+00 2111.00
IUUC-Ola-086639 Oryzias latipes 75.72 0.00e+00 1686.00
IUUC-Oga-088985 Otolemur garnettii 94.80 0.00e+00 2066.00
IUUC-Oar-089266 Ovis aries 88.33 0.00e+00 1885.00
IUUC-Pan-092029 Papio anubis 98.46 0.00e+00 2185.00
IUUC-Psi-094016 Pelodiscus sinensis 63.20 0.00e+00 1300.00
IUUC-Pfo-096319 Poecilia formosa 76.43 0.00e+00 1720.00
IUUC-Rno-105992 Rattus norvegicus 93.72 0.00e+00 2080.00
IUUC-Sha-107424 Sarcophilus harrisii 86.31 0.00e+00 1973.00
IUUC-Ssc-115400 Sus scrofa 95.90 0.00e+00 2096.00
IUUC-Tru-118665 Takifugu rubripes 75.66 0.00e+00 1720.00
IUUC-Tre-122048 Trichoderma reesei 43.70 0.00e+00 734.00
IUUC-Vda-130020 Verticillium dahliae 44.38 0.00e+00 724.00
IUUC-Xtr-131936 Xenopus tropicalis 77.69 0.00e+00 1781.00
Created Date 25-Jun-2017

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