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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063707
UUCD1 version UUC-MuM-00885
Ensembl Protein ID ENSMUSP00000013771.8
UniProt Accession Q9ERP3; TRI54_MOUSE
Genbank Protein ID AAG03076.1
Protein Name Tripartite motif-containing protein 54; Muscle-specific RING finger protein; Muscle-specific RING finger protein 3; RING finger protein 30
Genbank Nucleotide ID AF294790
Gene Name Trim54; Murf; Rnf30
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000062077.14 ENSMUST00000013771.14 ENSMUSP00000013771.8
ENSMUSG00000062077.14 ENSMUST00000202769.1 ENSMUSP00000144629.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarRAID2
Protein-protein Interaction
IIDiRefIndexHINTMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 5.70e-09 37.5 26 82
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw...........pglknssskefrCPlCr 46
           C+iCle+f++++++lpC+H  +++C + +                ss ++frCP Cr
   Q: 26   CPICLEMFSKPVVILPCQHNLCRKCANDVfqasnplwqsrGSTTVSSGGRFRCPSCR 82
           *************************87777777888899977777899********8 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     May bind and stabilize microtubules during myotubes formation.
 May bind and stabilize microtubules during myotubes formation.
Protein Sequence
(Fasta)
MNFTVGFKPL LGDAHNMDNL EKQLICPICL EMFSKPVVIL PCQHNLCRKC ANDVFQASNP 60
LWQSRGSTTV SSGGRFRCPS CRHEVVLDRH GVYGLQRNLL VENIIDIYKQ ESSRPLHAKA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063707|E3,RING|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAGGAGTGTA GACAGAGTGT CTGGAAATAG ACAGGGGTGA GAGGAGCTGT TAGGGGAAGG 60
GACAGGACTC TTCCAAGAGG GAGCAATAGC CGGGATCCCA AGAATCCAGT CAGCCTAAAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063707|E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0479--Metal-binding
KW-0493--Microtubule
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR017903--COS_domain
IPR033492--TRIM54
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS51262--COS
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX
SMART

SM00336--BBOX
SM00184--RING
Gene Ontology

GO:0005874--C:microtubule
GO:0005875--C:microtubule associated complex
GO:0030018--C:Z disc
GO:0008017--F:microtubule binding
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0055001--P:muscle cell development
GO:0007026--P:negative regulation of microtubule depolymerization
KEGG mmu:58522
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002282 Ailuropoda melanoleuca 96.74 2.00e-133 468.00
IUUC-Bta-013385 Bos taurus 93.17 3.00e-176 611.00
IUUC-Cja-019697 Callithrix jacchus 76.67 2.00e-135 474.00
IUUC-Cfa-020995 Canis familiaris 97.27 1.00e-168 585.00
IUUC-Cpo-021913 Cavia porcellus 95.05 0.00e+00 672.00
IUUC-Csa-023342 Chlorocebus sabaeus 95.28 0.00e+00 637.00
IUUC-Cin-025224 Ciona intestinalis 51.09 8.00e-94 337.00
IUUC-Csv-026374 Ciona savignyi 51.25 7.00e-81 293.00
IUUC-Dre-027562 Danio rerio 69.62 8.00e-144 503.00
IUUC-Dno-029582 Dasypus novemcinctus 97.57 8.00e-171 593.00
IUUC-Dor-031139 Dipodomys ordii 95.01 0.00e+00 649.00
IUUC-Ete-032346 Echinops telfairi 98.03 2.00e-108 385.00
IUUC-Eca-033645 Equus caballus 97.00 9.00e-178 615.00
IUUC-Eeu-035333 Erinaceus europaeus 69.12 1.00e-115 409.00
IUUC-Fca-035865 Felis catus 96.67 1.00e-180 625.00
IUUC-Fal-036978 Ficedula albicollis 76.78 2.00e-167 582.00
IUUC-Gga-040452 Gallus gallus 77.69 1.00e-164 572.00
IUUC-Ggo-044467 Gorilla gorilla 84.83 1.00e-169 588.00
IUUC-Hsa-046379 Homo sapiens 94.44 7.00e-175 606.00
IUUC-Itr-047912 Ictidomys tridecemlineatus 94.81 0.00e+00 638.00
IUUC-Lch-050029 Latimeria chalumnae 78.05 6.00e-152 530.00
IUUC-Loc-051801 Lepisosteus oculatus 80.62 7.00e-136 476.00
IUUC-Laf-054215 Loxodonta africana 94.78 0.00e+00 668.00
IUUC-Mcc-055027 Macaca mulatta 85.57 5.00e-179 620.00
IUUC-Meu-056412 Macropus eugenii 92.74 1.00e-166 578.00
IUUC-Mmr-060920 Microcebus murinus 95.00 0.00e+00 648.00
IUUC-Mdo-062832 Monodelphis domestica 96.35 9.00e-165 572.00
IUUC-Mlu-067653 Myotis lucifugus 81.85 9.00e-139 486.00
IUUC-Nle-069020 Nomascus leucogenys 95.00 0.00e+00 630.00
IUUC-Opr-070577 Ochotona princeps 78.44 5.00e-143 500.00
IUUC-Ont-072491 Oreochromis niloticus 62.82 9.00e-121 426.00
IUUC-Oan-073101 Ornithorhynchus anatinus 94.85 4.00e-172 597.00
IUUC-Ocu-074454 Oryctolagus cuniculus 94.48 0.00e+00 626.00
IUUC-Oga-088361 Otolemur garnettii 97.60 4.00e-175 607.00
IUUC-Oar-089950 Ovis aries 78.69 1.00e-139 488.00
IUUC-Ptr-090785 Pan troglodytes 84.58 6.00e-169 587.00
IUUC-Pan-092344 Papio anubis 95.56 0.00e+00 640.00
IUUC-Pab-098322 Pongo abelii 91.94 1.00e-172 598.00
IUUC-Pca-100385 Procavia capensis 75.16 3.00e-121 427.00
IUUC-Rno-105134 Rattus norvegicus 96.69 0.00e+00 696.00
IUUC-Sha-106768 Sarcophilus harrisii 95.74 9.00e-178 615.00
IUUC-Tgu-117494 Taeniopygia guttata 80.43 5.00e-158 550.00
Created Date 25-Jun-2017

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