iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	11864566

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	0.0013	19.0	87	130

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 100  aglldrlpeeilveilklldkeellraarvcrrwqelasqkalw 143
              + ++p+ei  +i+++l+k++ll+a +vc+r++ + ++++ w
   Q: 87   PFKKYSIPDEITEQIFSNLKKKDLLSAMLVCHRFYGIGHKSRNW 130
           556779****************************9777766665 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MSRVIGRLPS TLEDNGPSEN EHCVETVFSD ETISIFPCYN LYPKKSLRLS VSGNSEKLKS 60
INLNCKNLVE DEIAPIKRKD ARSIQNPFKK YSIPDEITEQ IFSNLKKKDL LSAMLVCHRF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGATTTGCGG TGGAGCGCGT TTGCATTGCA AAAACTCGCG CCAACCTAAA AAAGATTACC 60
GCGCCCGCGA GTTCATATTT ATTCAAATCA GCCCTGTTTT GAATTTATTT CAAGCAGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13516--LRR_6

SMART

SM00256--FBOX

Gene Ontology

GO:0016301--F:kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002197	Ailuropoda melanoleuca	28.48	9.00e-32	129.00
IUUC-Apl-003453	Anas platyrhynchos	27.86	5.00e-27	113.00
IUUC-Aca-005185	Anolis carolinensis	29.73	2.00e-29	121.00
IUUC-Ame-010665	Astyanax mexicanus	24.31	1.00e-19	89.70
IUUC-Bta-013450	Bos taurus	29.01	9.00e-33	132.00
IUUC-Cja-019834	Callithrix jacchus	28.75	3.00e-30	124.00
IUUC-Cfa-020401	Canis familiaris	28.70	1.00e-33	136.00
IUUC-Cpo-022183	Cavia porcellus	28.70	5.00e-32	130.00
IUUC-Csa-023418	Chlorocebus sabaeus	29.36	2.00e-30	125.00
IUUC-Cho-024412	Choloepus hoffmanni	28.20	9.00e-24	103.00
IUUC-Cin-025248	Ciona intestinalis	25.99	2.00e-29	122.00
IUUC-Csv-026189	Ciona savignyi	25.61	1.00e-27	116.00
IUUC-Dre-028032	Danio rerio	24.62	4.00e-29	120.00
IUUC-Dno-029222	Dasypus novemcinctus	27.78	6.00e-32	130.00
IUUC-Dor-030505	Dipodomys ordii	26.32	2.00e-15	75.90
IUUC-Dme-031972	Drosophila melanogaster	28.23	1.00e-31	129.00
IUUC-Ete-032234	Echinops telfairi	27.07	5.00e-13	67.40
IUUC-Eca-033944	Equus caballus	28.70	3.00e-33	134.00
IUUC-Eeu-035008	Erinaceus europaeus	27.92	2.00e-21	94.70
IUUC-Fca-035412	Felis catus	28.40	3.00e-33	134.00
IUUC-Fal-037337	Ficedula albicollis	28.09	5.00e-26	110.00
IUUC-Gmo-038934	Gadus morhua	24.63	4.00e-09	54.70
IUUC-Gga-041152	Gallus gallus	28.88	8.00e-34	137.00
IUUC-Gac-041819	Gasterosteus aculeatus	23.19	3.00e-24	104.00
IUUC-Ggo-045479	Gorilla gorilla	28.89	9.00e-22	96.70
IUUC-Hsa-046512	Homo sapiens	29.05	2.00e-30	125.00
IUUC-Itr-048515	Ictidomys tridecemlineatus	29.32	1.00e-33	135.00
IUUC-Lch-050115	Latimeria chalumnae	29.19	1.00e-31	129.00
IUUC-Loc-052554	Lepisosteus oculatus	26.39	3.00e-26	111.00
IUUC-Laf-053563	Loxodonta africana	27.47	1.00e-31	129.00
IUUC-Mcc-055143	Macaca mulatta	29.36	2.00e-30	125.00
IUUC-Meu-056593	Macropus eugenii	32.76	1.00e-12	66.20
IUUC-Mga-060084	Meleagris gallopavo	28.73	9.00e-24	102.00
IUUC-Mmr-060660	Microcebus murinus	28.09	2.00e-31	128.00
IUUC-Mdo-062363	Monodelphis domestica	25.46	2.00e-22	99.00
IUUC-Mmu-063287	Mus musculus	26.23	1.00e-28	119.00
IUUC-Mpu-065791	Mustela putorius furo	28.40	5.00e-33	134.00
IUUC-Mlu-067714	Myotis lucifugus	29.45	1.00e-30	125.00
IUUC-Nle-069823	Nomascus leucogenys	29.05	3.00e-30	124.00
IUUC-Ont-071820	Oreochromis niloticus	23.89	3.00e-12	64.70
IUUC-Ocu-074868	Oryctolagus cuniculus	28.09	3.00e-32	131.00
IUUC-Ola-086608	Oryzias latipes	27.11	8.00e-15	73.60
IUUC-Oga-089044	Otolemur garnettii	28.40	4.00e-32	130.00
IUUC-Oar-089650	Ovis aries	29.63	1.00e-33	136.00
IUUC-Ptr-090743	Pan troglodytes	29.05	2.00e-30	125.00
IUUC-Pan-092501	Papio anubis	29.36	1.00e-30	125.00
IUUC-Psi-094032	Pelodiscus sinensis	26.63	3.00e-30	125.00
IUUC-Pfo-097279	Poecilia formosa	25.53	2.00e-14	72.40
IUUC-Pab-097821	Pongo abelii	28.89	1.00e-21	96.30
IUUC-Pca-100100	Procavia capensis	27.34	3.00e-22	97.80
IUUC-Pva-103181	Pteropus vampyrus	27.90	4.00e-20	91.30
IUUC-Rno-105091	Rattus norvegicus	27.16	2.00e-30	125.00
IUUC-Sha-107226	Sarcophilus harrisii	26.32	6.00e-24	103.00
IUUC-Ssc-115665	Sus scrofa	28.40	5.00e-32	130.00
IUUC-Tgu-116982	Taeniopygia guttata	26.43	5.00e-24	103.00
IUUC-Tru-118276	Takifugu rubripes	25.00	9.00e-15	73.60
IUUC-Tsy-119074	Tarsius syrichta	29.74	1.00e-22	99.40
IUUC-Tni-120702	Tetraodon nigroviridis	27.15	3.00e-10	57.80
IUUC-Tbe-127990	Tupaia belangeri	29.61	3.00e-18	84.70
IUUC-Ttr-128661	Tursiops truncatus	24.00	3.00e-12	65.10
IUUC-Xtr-132166	Xenopus tropicalis	29.54	2.00e-29	122.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence