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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063826
UUCD1 version UUC-MuM-00110
Ensembl Protein ID ENSMUSP00000032094.5
UniProt Accession Q8BID8; Q3U2Q9; Q8R5H7; Q8VDT7; Q922N5; FXL14_MOUSE
Genbank Protein ID BAC39201.1; BAE33081.1; AAH06913.1; AAH21329.1; AAL75967.1
Protein Name F-box/LRR-repeat protein 14; F-box and leucine-rich repeat protein 14
Genbank Nucleotide ID AK084506; AK155154; BC006913; BC021329; AF467463
Gene Name Fbxl14; Fbl14; Ppa
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000030019.6 ENSMUST00000032094.6 ENSMUSP00000032094.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarmiRNAMapRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/SCF/F-box 63.24 1.00e-140 496.00 IUUC-Dme-031589
E3 adaptor/Cullin RING/SCF/F-box 100.00 0.00e+00 793.00 IUUC-Hsa-046454
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mus musculus
Functional Description
(View)

Functional Description


     Substrate-recognition component of some (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1 (By similarity).
 Substrate-recognition component of some (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1 (By similarity).
Protein Sequence
(Fasta)
METHISCLFP ELLAMIFGYL DVRDKGRAAQ VCTAWRDAAY HKSVWRGVEA KLHLRRANPS 60
LFPSLQARGI RRVQILSLRR SLSYVIQGMA NIESLNLSGC YNLTDNGLGH AFVQEIGSLR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063826|E3,F-box|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGGCCGCGC GGGGGCGGGA AGGGCGGCAG GAAGGAAGCG CCGCTCGGAC GCGCCGGGAG 60
GAGGAGCGGC GGCCCGGCCG GAAGGCGGGG AGGGGCGGCC GTTGGCCCGC GGCGGGCCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063826|E3,F-box|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0433--Leucine-rich repeat
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp
Pfam

PF12937--F-box-like
PF13516--LRR_6
SMART

SM00367--LRR_CC
Gene Ontology

GO:0005737--C:cytoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG mmu:101358
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002246 Ailuropoda melanoleuca 100.00 0.00e+00 796.00
IUUC-Apl-003553 Anas platyrhynchos 95.30 1.00e-149 522.00
IUUC-Aca-004590 Anolis carolinensis 94.15 3.00e-98 350.00
IUUC-Ame-011225 Astyanax mexicanus 92.00 0.00e+00 747.00
IUUC-Bta-012544 Bos taurus 100.00 0.00e+00 796.00
IUUC-Cja-019913 Callithrix jacchus 100.00 0.00e+00 793.00
IUUC-Cfa-020197 Canis familiaris 100.00 6.00e-176 609.00
IUUC-Cpo-022294 Cavia porcellus 97.14 0.00e+00 739.00
IUUC-Csa-023181 Chlorocebus sabaeus 100.00 0.00e+00 764.00
IUUC-Dre-028033 Danio rerio 92.75 0.00e+00 750.00
IUUC-Dno-029787 Dasypus novemcinctus 100.00 0.00e+00 796.00
IUUC-Dme-031589 Drosophila melanogaster 63.24 2.00e-141 496.00
IUUC-Ete-032977 Echinops telfairi 100.00 0.00e+00 793.00
IUUC-Eca-033691 Equus caballus 94.26 0.00e+00 730.00
IUUC-Fca-035767 Felis catus 100.00 0.00e+00 782.00
IUUC-Fal-037251 Ficedula albicollis 95.00 0.00e+00 727.00
IUUC-Gmo-039594 Gadus morhua 90.48 0.00e+00 733.00
IUUC-Ggr-039725 Gaeumannomyces graminis 28.24 3.00e-31 130.00
IUUC-Gga-040176 Gallus gallus 95.24 0.00e+00 726.00
IUUC-Gac-041451 Gasterosteus aculeatus 91.48 0.00e+00 740.00
IUUC-Ggo-044920 Gorilla gorilla 100.00 4.00e-160 556.00
IUUC-Hsa-046454 Homo sapiens 100.00 0.00e+00 793.00
IUUC-Itr-048932 Ictidomys tridecemlineatus 100.00 0.00e+00 681.00
IUUC-Kpa-049189 Komagataella pastoris 28.78 4.00e-21 97.10
IUUC-Lch-050647 Latimeria chalumnae 92.75 0.00e+00 749.00
IUUC-Loc-051978 Lepisosteus oculatus 92.50 0.00e+00 749.00
IUUC-Mcc-055878 Macaca mulatta 100.00 0.00e+00 793.00
IUUC-Meu-056536 Macropus eugenii 99.47 0.00e+00 742.00
IUUC-Mmr-061440 Microcebus murinus 99.75 0.00e+00 794.00
IUUC-Mdo-062821 Monodelphis domestica 99.75 0.00e+00 795.00
IUUC-Mpu-066312 Mustela putorius furo 100.00 0.00e+00 796.00
IUUC-Mlu-067341 Myotis lucifugus 99.75 0.00e+00 795.00
IUUC-Nle-069771 Nomascus leucogenys 100.00 0.00e+00 793.00
IUUC-Ont-072668 Oreochromis niloticus 92.00 0.00e+00 745.00
IUUC-Ocu-073972 Oryctolagus cuniculus 99.75 0.00e+00 793.00
IUUC-Ola-087359 Oryzias latipes 92.15 0.00e+00 738.00
IUUC-Oga-088437 Otolemur garnettii 100.00 0.00e+00 796.00
IUUC-Ptr-091419 Pan troglodytes 97.70 0.00e+00 749.00
IUUC-Pan-091932 Papio anubis 100.00 0.00e+00 794.00
IUUC-Psi-093623 Pelodiscus sinensis 95.35 3.00e-152 530.00
IUUC-Pma-094244 Petromyzon marinus 78.35 7.00e-148 516.00
IUUC-Pfo-097490 Poecilia formosa 92.00 0.00e+00 744.00
IUUC-Pab-098368 Pongo abelii 100.00 0.00e+00 793.00
IUUC-Pca-100216 Procavia capensis 100.00 3.00e-156 543.00
IUUC-Sha-107456 Sarcophilus harrisii 97.58 0.00e+00 630.00
IUUC-Tru-117892 Takifugu rubripes 91.96 0.00e+00 741.00
IUUC-Vpa-130165 Vicugna pacos 98.97 2.00e-163 567.00
IUUC-Xtr-132620 Xenopus tropicalis 95.00 0.00e+00 764.00
Created Date 25-Jun-2017

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