iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011608

Ensembl Protein ID

ENSAMXP00000006988.1

UniProt Accession

W5KHC6; W5KHC6_ASTMX

Genbank Protein ID

ENSAMXP00000006988

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01101166

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000006803.1	ENSAMXT00000006988.1	ENSAMXP00000006988.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.20e-17	63.9	795	847

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            + y++ a +  eL+l++Gd+v++ +k   d+gW+kg  e++g+ G fP+ +ve+
   Q: 795  VARYNFAARDMRELSLREGDIVKIYSKIGGDQGWWKG--EANGRIGWFPSTYVEE 847
           578**********************************..9*************86 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MEEWRQCGRW LIDCKVLPPN HRVVWPSAVV FDLAQALRDG VLLCQMLHNL SPGSVDLKQI 60
NFRPQMSQFL CLKNIRTFLK VCHDKFGLRN SELFDPFDLF DVRDFGKVIS ALSRISHNSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAACGGGA GAAAACGGGA GGAAAAGAGG ACTTTAAAAC GACGGGAGGA CTACAGAGGA 60
CGGAGGAGGG ATATGCGGAG GGACGGGAGG AGTTAATGCG TGTTTTTGTG GTTTTTAACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001437	Ailuropoda melanoleuca	78.67	0.00e+00	1285.00
IUUC-Apl-003262	Anas platyrhynchos	79.64	0.00e+00	1352.00
IUUC-Ath-007340	Arabidopsis thaliana	38.30	1.10e-02	34.30
IUUC-Bta-013147	Bos taurus	75.44	0.00e+00	1082.00
IUUC-Cel-018578	Caenorhabditis elegans	32.13	4.00e-79	289.00
IUUC-Cja-018877	Callithrix jacchus	75.37	0.00e+00	1177.00
IUUC-Cfa-020315	Canis familiaris	80.54	0.00e+00	1074.00
IUUC-Cpo-021543	Cavia porcellus	76.02	0.00e+00	1087.00
IUUC-Csa-024204	Chlorocebus sabaeus	77.75	0.00e+00	1376.00
IUUC-Cin-025115	Ciona intestinalis	37.33	9.00e-155	540.00
IUUC-Csv-025995	Ciona savignyi	36.57	1.00e-154	540.00
IUUC-Dre-028308	Danio rerio	91.36	0.00e+00	1637.00
IUUC-Dno-029584	Dasypus novemcinctus	77.47	0.00e+00	1000.00
IUUC-Dor-031014	Dipodomys ordii	70.14	0.00e+00	1042.00
IUUC-Eca-033448	Equus caballus	77.21	0.00e+00	1349.00
IUUC-Eeu-035182	Erinaceus europaeus	72.14	7.00e-171	594.00
IUUC-Fca-035460	Felis catus	77.22	0.00e+00	1124.00
IUUC-Fal-036684	Ficedula albicollis	79.69	0.00e+00	1392.00
IUUC-Gmo-038816	Gadus morhua	86.65	0.00e+00	1233.00
IUUC-Gga-040999	Gallus gallus	82.69	0.00e+00	1389.00
IUUC-Gac-041353	Gasterosteus aculeatus	88.00	0.00e+00	1293.00
IUUC-Ggo-044558	Gorilla gorilla	79.11	0.00e+00	1385.00
IUUC-Hsa-046208	Homo sapiens	79.34	0.00e+00	1387.00
IUUC-Itr-047931	Ictidomys tridecemlineatus	75.77	0.00e+00	1021.00
IUUC-Loc-052827	Lepisosteus oculatus	87.26	0.00e+00	1565.00
IUUC-Laf-054009	Loxodonta africana	75.62	0.00e+00	1301.00
IUUC-Mcc-055054	Macaca mulatta	79.34	0.00e+00	1387.00
IUUC-Mla-059044	Melampsora laricipopulina	23.26	5.00e-19	90.10
IUUC-Mga-060106	Meleagris gallopavo	79.98	0.00e+00	1366.00
IUUC-Mmr-061118	Microcebus murinus	78.09	0.00e+00	1349.00
IUUC-Mdo-062380	Monodelphis domestica	80.54	0.00e+00	1144.00
IUUC-Mmu-063135	Mus musculus	78.82	0.00e+00	1366.00
IUUC-Mpu-066135	Mustela putorius furo	79.85	0.00e+00	1252.00
IUUC-Nle-069465	Nomascus leucogenys	71.90	0.00e+00	1233.00
IUUC-Ont-071945	Oreochromis niloticus	87.19	0.00e+00	1527.00
IUUC-Oan-073384	Ornithorhynchus anatinus	75.51	0.00e+00	1042.00
IUUC-Ola-087499	Oryzias latipes	88.18	0.00e+00	1215.00
IUUC-Oga-088444	Otolemur garnettii	79.48	0.00e+00	1125.00
IUUC-Oar-089576	Ovis aries	74.22	0.00e+00	1026.00
IUUC-Ptr-090507	Pan troglodytes	78.32	0.00e+00	1353.00
IUUC-Pan-092325	Papio anubis	82.04	0.00e+00	1377.00
IUUC-Psi-094021	Pelodiscus sinensis	83.22	0.00e+00	1384.00
IUUC-Pma-094372	Petromyzon marinus	52.73	0.00e+00	694.00
IUUC-Pfo-096732	Poecilia formosa	89.77	0.00e+00	1588.00
IUUC-Pab-098426	Pongo abelii	68.78	0.00e+00	998.00
IUUC-Pca-100295	Procavia capensis	77.16	0.00e+00	1249.00
IUUC-Rno-105332	Rattus norvegicus	77.98	0.00e+00	1342.00
IUUC-Sha-106529	Sarcophilus harrisii	77.95	0.00e+00	1086.00
IUUC-Ssc-116176	Sus scrofa	76.46	0.00e+00	1215.00
IUUC-Tgu-116917	Taeniopygia guttata	78.62	0.00e+00	1234.00
IUUC-Tru-118398	Takifugu rubripes	85.02	0.00e+00	1069.00
IUUC-Tni-120819	Tetraodon nigroviridis	85.60	0.00e+00	1302.00
IUUC-Xtr-132747	Xenopus tropicalis	76.29	0.00e+00	1316.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence