iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067336

Ensembl Protein ID

ENSMLUP00000014905.2

UniProt Accession

G1PUF2; G1PUF2_MYOLU

Genbank Protein ID

ENSMLUP00000014905

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02027353

Gene Name

TSG101

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000016353.2	ENSMLUT00000016356.2	ENSMLUP00000014905.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/UBC-like/UBD_UEV	1.60e-66	222.6	2	145

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/UBC-like/UBD_UEV

   S: 1    AvsesslkkvpskykdkrltvrellnliesykslkpktasfvlnDgesreLlrltGtipvpergitynipiilwlletYPekPPfvsvk 89
           Avses+lkk++skyk+++ltvre++n+i+ yk+lkp+++s+v+nDg+sreL++ltGt+pv +rg+tynipi+lwll+tYP++PP+++vk
   Q: 2    AVSESQLKKMVSKYKYRDLTVRETINVITLYKDLKPVLDSYVFNDGSSRELMNLTGTVPVLYRGNTYNIPICLWLLDTYPYNPPICFVK 90
           89*************************************************************************************** PP
   S: 90   ekidmntikssnehvdpnGkialpvLhkWknpasnlvelvqelivllskeppklsrp 146
           ++++m tik++ +hvd+nGki+lp+Lh+Wk+p+s+l+ l+q++iv++++epp++srp
   Q: 91   PTSSM-TIKTG-KHVDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVFSRP 145
           *****.*****.*******************************************98 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MAVSESQLKK MVSKYKYRDL TVRETINVIT LYKDLKPVLD SYVFNDGSSR ELMNLTGTVP 60
VLYRGNTYNI PICLWLLDTY PYNPPICFVK PTSSMTIKTG KHVDANGKIY LPYLHEWKHP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGCCGCCA TGGCCGTGTC GGAGAGCCAG CTCAAGAAGA TGGTGTCCAA GGTGAGGCCG 60
CGACGCGCTC GCCCCGGCGC GCGCCCACCG CCGCCTTCCG TGCCCGGGCC GGCATGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR017916--SB_dom
IPR016135--UBQ-conjugating_enzyme/RWD
IPR008883--UEV_N

PROSITE

PS51312--SB
PS51322--UEV

Pfam

PF05743--UEV
PF09454--Vps23_core

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0000813--C:ESCRT I complex
GO:0070062--C:extracellular exosome
GO:0005770--C:late endosome
GO:0005730--C:nucleolus
GO:0005886--C:plasma membrane
GO:0003714--F:transcription corepressor activity
GO:0046790--F:virion binding
GO:0007050--P:cell cycle arrest
GO:0006464--P:cellular protein modification process
GO:1990182--P:exosomal secretion
GO:0030216--P:keratinocyte differentiation
GO:0008285--P:negative regulation of cell proliferation
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1903543--P:positive regulation of exosomal secretion
GO:2000397--P:positive regulation of ubiquitin-dependent endocytosis
GO:1903774--P:positive regulation of viral budding via host ESCRT complex
GO:1902188--P:positive regulation of viral release from host cell
GO:0015031--P:protein transport
GO:0001558--P:regulation of cell growth
GO:1903551--P:regulation of extracellular exosome assembly
GO:0043405--P:regulation of MAP kinase activity
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0046755--P:viral budding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001072	Aegilops tauschii	40.00	4.00e-21	95.50
IUUC-Aml-002415	Ailuropoda melanoleuca	96.93	0.00e+00	733.00
IUUC-Atr-002875	Amborella trichopoda	28.85	9.00e-37	147.00
IUUC-Apl-003473	Anas platyrhynchos	88.27	0.00e+00	681.00
IUUC-Aca-004573	Anolis carolinensis	90.56	0.00e+00	677.00
IUUC-Aly-006164	Arabidopsis lyrata	42.16	7.00e-21	94.70
IUUC-Ath-006575	Arabidopsis thaliana	42.16	7.00e-21	94.70
IUUC-Ago-007755	Ashbya gossypii	25.00	1.00e-05	44.30
IUUC-Acl-008218	Aspergillus clavatus	38.76	3.00e-25	110.00
IUUC-Afl-008597	Aspergillus flavus	39.85	2.00e-25	110.00
IUUC-Afu-009017	Aspergillus fumigatus	37.21	7.00e-23	102.00
IUUC-Ani-009468	Aspergillus nidulans	38.64	5.00e-21	95.90
IUUC-Ang-009755	Aspergillus niger	36.51	2.00e-22	100.00
IUUC-Aor-010072	Aspergillus oryzae	38.35	1.00e-25	111.00
IUUC-Ate-010400	Aspergillus terreus	38.76	1.00e-24	108.00
IUUC-Ame-011620	Astyanax mexicanus	80.77	0.00e+00	645.00
IUUC-Bgr-012136	Blumeria graminis	35.77	4.00e-24	105.00
IUUC-Bta-012557	Bos taurus	97.19	0.00e+00	724.00
IUUC-Bci-013881	Botrytis cinerea	37.41	5.00e-26	112.00
IUUC-Bdi-014325	Brachypodium distachyon	32.11	3.00e-15	75.90
IUUC-Bol-016308	Brassica oleracea	40.00	2.00e-25	110.00
IUUC-Bra-017605	Brassica rapa	39.52	1.00e-25	110.00
IUUC-Cel-018697	Caenorhabditis elegans	48.84	1.00e-37	150.00
IUUC-Cja-018963	Callithrix jacchus	90.56	0.00e+00	715.00
IUUC-Cfa-020472	Canis familiaris	96.93	0.00e+00	730.00
IUUC-Cpo-022001	Cavia porcellus	98.72	0.00e+00	739.00
IUUC-Cre-022918	Chlamydomonas reinhardtii	30.05	2.00e-31	130.00
IUUC-Csa-023959	Chlorocebus sabaeus	97.95	0.00e+00	704.00
IUUC-Cho-024389	Choloepus hoffmanni	55.45	1.00e-38	154.00
IUUC-Cin-025688	Ciona intestinalis	44.53	1.00e-99	356.00
IUUC-Cne-026904	Cryptococcus neoformans	29.09	1.00e-14	74.70
IUUC-Cme-027280	Cyanidioschyzon merolae	40.00	1.00e-18	87.00
IUUC-Dre-027913	Danio rerio	81.03	3.00e-177	614.00
IUUC-Dno-029672	Dasypus novemcinctus	96.93	0.00e+00	743.00
IUUC-Dor-030175	Dipodomys ordii	97.00	5.00e-94	337.00
IUUC-Dse-031375	Dothistroma septosporum	32.85	7.00e-23	102.00
IUUC-Dme-031736	Drosophila melanogaster	48.79	5.00e-97	347.00
IUUC-Ete-032343	Echinops telfairi	92.33	0.00e+00	699.00
IUUC-Eca-033926	Equus caballus	97.19	0.00e+00	727.00
IUUC-Eeu-034940	Erinaceus europaeus	89.51	0.00e+00	715.00
IUUC-Fca-035491	Felis catus	96.68	0.00e+00	714.00
IUUC-Fal-037508	Ficedula albicollis	90.56	0.00e+00	677.00
IUUC-Fox-037937	Fusarium oxysporum	32.31	4.00e-21	96.30
IUUC-Fso-038091	Fusarium solani	36.03	7.00e-25	108.00
IUUC-Gmo-039427	Gadus morhua	78.66	1.00e-172	598.00
IUUC-Ggr-039724	Gaeumannomyces graminis	36.57	3.00e-25	110.00
IUUC-Gga-040998	Gallus gallus	88.24	0.00e+00	699.00
IUUC-Gac-041356	Gasterosteus aculeatus	80.72	0.00e+00	642.00
IUUC-Gma-043566	Glycine max	38.10	5.00e-25	108.00
IUUC-Ggo-044967	Gorilla gorilla	97.95	0.00e+00	704.00
IUUC-Hsa-046686	Homo sapiens	97.95	0.00e+00	704.00
IUUC-Hvu-047430	Hordeum vulgare	40.00	3.00e-21	95.90
IUUC-Itr-047929	Ictidomys tridecemlineatus	98.21	2.00e-110	391.00
IUUC-Kpa-049287	Komagataella pastoris	30.25	2.00e-15	77.00
IUUC-Lch-050597	Latimeria chalumnae	86.99	0.00e+00	678.00
IUUC-Lpe-051090	Leersia perrieri	38.26	2.00e-20	93.20
IUUC-Loc-052399	Lepisosteus oculatus	81.12	2.00e-178	617.00
IUUC-Lma-053249	Leptosphaeria maculans	30.70	9.00e-14	72.00
IUUC-Laf-053766	Loxodonta africana	98.47	0.00e+00	737.00
IUUC-Mcc-055641	Macaca mulatta	97.95	0.00e+00	704.00
IUUC-Meu-055919	Macropus eugenii	90.80	5.00e-172	596.00
IUUC-Mor-056970	Magnaporthe oryzae	37.69	2.00e-24	107.00
IUUC-Mpo-057345	Magnaporthe poae	36.15	4.00e-23	102.00
IUUC-Mtr-058436	Medicago truncatula	29.16	4.00e-35	142.00
IUUC-Mla-059037	Melampsora laricipopulina	35.17	1.00e-25	111.00
IUUC-Mga-059263	Meleagris gallopavo	87.53	0.00e+00	672.00
IUUC-Mvi-060463	Microbotryum violaceum	28.30	2.00e-16	80.50
IUUC-Mmr-060915	Microcebus murinus	97.70	0.00e+00	731.00
IUUC-Mdo-062449	Monodelphis domestica	94.12	0.00e+00	694.00
IUUC-Mmu-063151	Mus musculus	94.63	0.00e+00	709.00
IUUC-Mac-065581	Musa acuminata	35.66	3.00e-22	99.40
IUUC-Mpu-066621	Mustela putorius furo	96.93	0.00e+00	733.00
IUUC-Nfi-068530	Neosartorya fischeri	37.98	6.00e-23	102.00
IUUC-Ncr-068785	Neurospora crassa	36.03	5.00e-25	109.00
IUUC-Nle-069972	Nomascus leucogenys	97.95	0.00e+00	704.00
IUUC-Opr-071150	Ochotona princeps	68.29	1.00e-123	436.00
IUUC-Ont-071366	Oreochromis niloticus	81.79	0.00e+00	641.00
IUUC-Oan-073290	Ornithorhynchus anatinus	93.48	1.00e-105	375.00
IUUC-Ocu-074351	Oryctolagus cuniculus	97.95	0.00e+00	734.00
IUUC-Oba-075338	Oryza barthii	37.50	3.00e-11	62.40
IUUC-Obr-076135	Oryza brachyantha	26.32	1.00e-28	120.00
IUUC-Ogl-077182	Oryza glaberrima	37.04	5.00e-17	82.00
IUUC-Ogu-078281	Oryza glumaepatula	37.39	4.00e-20	92.40
IUUC-Oin-079068	Oryza indica	36.45	1.00e-16	81.30
IUUC-Olo-080460	Oryza longistaminata	35.80	1.00e-08	52.80
IUUC-Ome-081781	Oryza meridionalis	25.41	8.00e-18	85.10
IUUC-Oni-082517	Oryza nivara	26.92	4.00e-21	95.90
IUUC-Opu-084101	Oryza punctata	37.04	4.00e-17	82.40
IUUC-Oru-084556	Oryza rufipogon	37.04	5.00e-17	82.00
IUUC-Osa-086264	Oryza sativa	37.04	5.00e-17	82.00
IUUC-Ola-087252	Oryzias latipes	93.29	3.00e-69	253.00
IUUC-Olu-087610	Ostreococcus lucimarinus	26.70	2.00e-13	70.10
IUUC-Oga-088304	Otolemur garnettii	97.19	0.00e+00	729.00
IUUC-Oar-089734	Ovis aries	97.19	0.00e+00	724.00
IUUC-Ptr-091476	Pan troglodytes	97.95	0.00e+00	704.00
IUUC-Pan-092341	Papio anubis	97.95	0.00e+00	704.00
IUUC-Psi-093470	Pelodiscus sinensis	92.73	0.00e+00	674.00
IUUC-Pma-094143	Petromyzon marinus	63.54	3.00e-132	464.00
IUUC-Pno-095069	Phaeosphaeria nodorum	31.93	1.00e-14	74.30
IUUC-Ppa-095933	Physcomitrella patens	28.42	2.00e-36	146.00
IUUC-Pfo-096321	Poecilia formosa	79.74	3.00e-176	610.00
IUUC-Pab-098527	Pongo abelii	97.73	1.00e-180	625.00
IUUC-Pop-099323	Populus trichocarpa	28.21	4.00e-37	149.00
IUUC-Pca-101044	Procavia capensis	79.54	3.00e-159	554.00
IUUC-Ppe-101458	Prunus persica	41.67	5.00e-27	115.00
IUUC-Pva-103014	Pteropus vampyrus	87.98	5.00e-175	606.00
IUUC-Pgr-103615	Puccinia graminis	35.34	3.00e-20	93.60
IUUC-Ptt-103826	Puccinia triticina	39.22	2.00e-16	80.50
IUUC-Pte-104171	Pyrenophora teres	35.29	1.00e-21	97.80
IUUC-Pyt-104433	Pyrenophora triticirepentis	33.01	2.00e-10	60.50
IUUC-Rno-105957	Rattus norvegicus	93.61	0.00e+00	702.00
IUUC-Sce-106262	Saccharomyces cerevisiae	25.37	4.00e-10	59.30
IUUC-Sha-107607	Sarcophilus harrisii	94.84	4.00e-175	607.00
IUUC-Spo-108175	Schizosaccharomyces pombe	30.56	1.20e-02	34.70
IUUC-Ssl-108672	Sclerotinia sclerotiorum	35.29	4.00e-25	109.00
IUUC-Smo-108973	Selaginella moellendorffii	37.72	6.00e-21	95.10
IUUC-Sly-111373	Solanum lycopersicum	37.30	2.00e-24	106.00
IUUC-Stu-112844	Solanum tuberosum	36.51	1.00e-23	103.00
IUUC-Sar-113653	Sorex araneus	84.32	6.00e-176	609.00
IUUC-Sbi-114390	Sorghum bicolor	33.88	5.00e-20	92.00
IUUC-Sre-115200	Sporisorium reilianum	36.84	5.00e-24	105.00
IUUC-Ssc-115888	Sus scrofa	98.24	5.00e-113	399.00
IUUC-Tgu-117506	Taeniopygia guttata	84.15	0.00e+00	685.00
IUUC-Tru-118063	Takifugu rubripes	79.03	4.00e-172	597.00
IUUC-Tsy-118851	Tarsius syrichta	73.85	4.00e-144	504.00
IUUC-Tni-120010	Tetraodon nigroviridis	78.83	2.00e-170	591.00
IUUC-Tca-121182	Theobroma cacao	37.30	4.00e-21	95.90
IUUC-Tre-122040	Trichoderma reesei	36.15	1.00e-22	100.00
IUUC-Tvi-122660	Trichoderma virens	39.71	1.00e-26	114.00
IUUC-Tae-124561	Triticum aestivum	40.00	4.00e-21	95.50
IUUC-Tur-126651	Triticum urartu	40.00	6.00e-21	94.70
IUUC-Tme-127184	Tuber melanosporum	47.32	1.00e-26	114.00
IUUC-Tbe-127894	Tupaia belangeri	82.50	4.00e-90	324.00
IUUC-Ttr-128264	Tursiops truncatus	88.24	0.00e+00	702.00
IUUC-Uma-129407	Ustilago maydis	35.53	1.00e-24	108.00
IUUC-Vda-130002	Verticillium dahliae	29.73	3.00e-16	80.10
IUUC-Vpa-130156	Vicugna pacos	96.00	3.00e-98	351.00
IUUC-Vvi-131062	Vitis vinifera	29.30	4.00e-31	128.00
IUUC-Xtr-132332	Xenopus tropicalis	80.15	7.00e-63	232.00
IUUC-Xma-133186	Xiphophorus maculatus	77.28	2.00e-176	611.00
IUUC-Yli-134500	Yarrowia lipolytica	33.55	1.00e-12	67.40
IUUC-Zma-135391	Zea mays	34.45	1.00e-19	90.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence