iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-061990

UUCD1 version

UUC-MoD-00617

Ensembl Protein ID

ENSMODP00000001021.2

UniProt Accession

F7BHT0; F7BHT0_MONDO

Protein Name

Uncharacterized protein

Gene Name

KLHL12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000000855.3	ENSMODT00000001041.3	ENSMODP00000001021.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.50e-19	70.2	31	94
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.60e-14	50.8	130	161

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dv+l+v+++ f+ah+ivLaa+S++F a+f++el+e+  k+ v+i+++ ++ ++ ll+F+Yt ++
   Q: 31   CDVTLKVEQKDFPAHRIVLAACSDYFCAMFTSELSEKG-KPYVDIQGLTASTMEILLDFVYTETV 94
           9***********************************98.***********************987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclgi++fA++++c dL++aa+ f +khF+
   Q: 130  PSNCLGIRDFAETHNCVDLMQAAEVFSQKHFP 161
           89*****************************6 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

GNMAPKDIMT NSHAKSILNS MNSLRKSNTL CDVTLKVEQK DFPAHRIVLA ACSDYFCAMF 60
TSELSEKGKP YVDIQGLTAS TMEILLDFVY TETVHVTVEN VQELLPAACL LQLKGVKQAC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCATCGAAA ATGGAGGTAC CCTTCCACAA GTGGTTGGGT GGGGTGTTTT ATTCTCCCTC 60
TTCGCCCCAC CCCCACCCCA GTAATCACTT AAGATTGGGG GTAGTGAACG TCCTAAATAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0030134--C:ER to Golgi transport vesicle
GO:0000139--C:Golgi membrane
GO:0005815--C:microtubule organizing center
GO:0048208--P:COPII vesicle coating
GO:0006513--P:protein monoubiquitination
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002301	Ailuropoda melanoleuca	97.68	0.00e+00	1113.00
IUUC-Apl-003339	Anas platyrhynchos	96.53	0.00e+00	1024.00
IUUC-Aca-004418	Anolis carolinensis	95.92	0.00e+00	1109.00
IUUC-Ame-011906	Astyanax mexicanus	75.35	0.00e+00	872.00
IUUC-Bta-012979	Bos taurus	95.76	0.00e+00	1108.00
IUUC-Cja-019582	Callithrix jacchus	97.52	0.00e+00	1125.00
IUUC-Cfa-020716	Canis familiaris	98.06	0.00e+00	1135.00
IUUC-Cpo-022013	Cavia porcellus	97.88	0.00e+00	1133.00
IUUC-Csa-023424	Chlorocebus sabaeus	98.10	0.00e+00	1052.00
IUUC-Cho-024586	Choloepus hoffmanni	79.79	0.00e+00	880.00
IUUC-Dre-028344	Danio rerio	89.32	2.00e-168	584.00
IUUC-Dno-028854	Dasypus novemcinctus	98.06	0.00e+00	1135.00
IUUC-Dor-030403	Dipodomys ordii	97.88	0.00e+00	1131.00
IUUC-Ete-032963	Echinops telfairi	97.02	0.00e+00	986.00
IUUC-Eca-033282	Equus caballus	97.88	0.00e+00	1135.00
IUUC-Eeu-034933	Erinaceus europaeus	96.08	3.00e-139	488.00
IUUC-Fca-035487	Felis catus	98.06	0.00e+00	1135.00
IUUC-Fal-037059	Ficedula albicollis	96.09	0.00e+00	1103.00
IUUC-Gmo-039564	Gadus morhua	89.18	0.00e+00	1077.00
IUUC-Gga-040629	Gallus gallus	96.09	0.00e+00	1109.00
IUUC-Gac-042526	Gasterosteus aculeatus	89.93	0.00e+00	1084.00
IUUC-Ggo-044839	Gorilla gorilla	97.88	0.00e+00	1134.00
IUUC-Hsa-046742	Homo sapiens	97.88	0.00e+00	1134.00
IUUC-Itr-048958	Ictidomys tridecemlineatus	97.88	0.00e+00	1132.00
IUUC-Lch-049540	Latimeria chalumnae	93.26	0.00e+00	1115.00
IUUC-Loc-051923	Lepisosteus oculatus	93.09	0.00e+00	1086.00
IUUC-Laf-054370	Loxodonta africana	97.53	0.00e+00	1131.00
IUUC-Mcc-054852	Macaca mulatta	97.88	0.00e+00	1134.00
IUUC-Mor-057181	Magnaporthe oryzae	26.61	2.00e-10	60.10
IUUC-Mga-059486	Meleagris gallopavo	94.91	0.00e+00	1013.00
IUUC-Mmr-061777	Microcebus murinus	98.23	0.00e+00	1133.00
IUUC-Mmu-064053	Mus musculus	97.53	0.00e+00	1131.00
IUUC-Mpu-066623	Mustela putorius furo	84.55	0.00e+00	807.00
IUUC-Mlu-067648	Myotis lucifugus	97.35	0.00e+00	1155.00
IUUC-Nle-069714	Nomascus leucogenys	97.70	0.00e+00	1132.00
IUUC-Opr-071143	Ochotona princeps	91.87	0.00e+00	1045.00
IUUC-Ont-071848	Oreochromis niloticus	90.27	0.00e+00	1087.00
IUUC-Oan-073041	Ornithorhynchus anatinus	97.14	7.00e-164	569.00
IUUC-Ocu-074379	Oryctolagus cuniculus	97.53	0.00e+00	1132.00
IUUC-Oin-079973	Oryza indica	34.04	4.00e-34	139.00
IUUC-Ola-087469	Oryzias latipes	90.80	0.00e+00	1090.00
IUUC-Oga-088004	Otolemur garnettii	99.15	1.00e-139	488.00
IUUC-Oar-090144	Ovis aries	96.82	0.00e+00	1121.00
IUUC-Ptr-091406	Pan troglodytes	97.88	0.00e+00	1134.00
IUUC-Pan-092762	Papio anubis	96.83	0.00e+00	1114.00
IUUC-Psi-093391	Pelodiscus sinensis	95.57	0.00e+00	1110.00
IUUC-Pma-094134	Petromyzon marinus	73.82	0.00e+00	827.00
IUUC-Pfo-096404	Poecilia formosa	90.46	0.00e+00	1088.00
IUUC-Pab-098425	Pongo abelii	97.00	0.00e+00	1121.00
IUUC-Pop-099216	Populus trichocarpa	32.93	2.00e-29	123.00
IUUC-Pca-101093	Procavia capensis	99.31	2.00e-173	602.00
IUUC-Pva-102239	Pteropus vampyrus	87.28	0.00e+00	1013.00
IUUC-Rno-104921	Rattus norvegicus	97.70	0.00e+00	1134.00
IUUC-Sha-106625	Sarcophilus harrisii	99.12	0.00e+00	1143.00
IUUC-Sly-111189	Solanum lycopersicum	36.32	5.00e-27	114.00
IUUC-Sar-113468	Sorex araneus	85.50	0.00e+00	699.00
IUUC-Ssc-116106	Sus scrofa	97.70	0.00e+00	1131.00
IUUC-Tgu-117402	Taeniopygia guttata	73.63	0.00e+00	742.00
IUUC-Tru-117546	Takifugu rubripes	90.07	0.00e+00	1082.00
IUUC-Tsy-118802	Tarsius syrichta	88.52	0.00e+00	990.00
IUUC-Tni-119999	Tetraodon nigroviridis	90.36	0.00e+00	1075.00
IUUC-Tca-121074	Theobroma cacao	30.96	8.00e-38	152.00
IUUC-Tbe-127987	Tupaia belangeri	97.84	0.00e+00	949.00
IUUC-Ttr-128613	Tursiops truncatus	90.62	0.00e+00	1028.00
IUUC-Xtr-132401	Xenopus tropicalis	92.56	9.00e-175	605.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence