iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118286

UUCD1 version

UUC-TaR-00260

Ensembl Protein ID

ENSTRUP00000013090.1

UniProt Accession

H2SL05; H2SL05_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000005452.1	ENSTRUT00000013151.1	ENSTRUP00000013090.1
ENSTRUG00000005452.1	ENSTRUT00000013152.1	ENSTRUP00000013091.1
ENSTRUG00000005452.1	ENSTRUT00000013153.1	ENSTRUP00000013092.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.00e-10	43.2	340	378
E3 activity/RING/U-box	1.40e-14	55.2	336	383

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C   f++ p+++pCgH+f+++C ++          + rCPlC+
   Q: 340  CPLCIRLFFE-PVTTPCGHTFCKNCMERS------LDHNLRCPLCK 378
           **********.9*************9777......9*********7 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplte 52
           ++f Cp+   l+ +Pv++p+G+t+ ++++e+ l+++ + cP+++qpl+e
   Q: 336  SDFECPLCIRLFFEPVTTPCGHTFCKNCMERSLDHNLR-CPLCKQPLQE 383
           78******************************999999.********76 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

TPKMDLLECP ICLFLMSEPV TMSCGHTFCR RCVGGSLPPK CPSCKERFKQ REVKNIRNNV 60
LLIGVVEKCC PDETKVKCHV QEKLKANEFT EALRIATEGL DLVPHDQGLR LYRVEANWAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCCCAAAGA TGGACCTGCT GGAGTGTCCG ATATGTCTCT TCCTGATGTC CGAGCCCGTC 60
ACCATGTCGT GCGGACACAC GTTCTGCCGG AGGTGTGTCG GAGGCTCCCT CCCACCCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51787--LON_N
PS50293--TPR_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02190--LON_substr_bdg
PF13445--zf-RING_UBOX

SMART

SM00464--LON
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-010916	Astyanax mexicanus	61.37	0.00e+00	742.00
IUUC-Cre-022730	Chlamydomonas reinhardtii	34.40	3.00e-09	55.50
IUUC-Dre-028300	Danio rerio	77.33	2.00e-160	559.00
IUUC-Fal-037635	Ficedula albicollis	67.37	9.00e-114	403.00
IUUC-Gmo-038475	Gadus morhua	67.24	3.00e-134	471.00
IUUC-Gga-040973	Gallus gallus	66.55	3.00e-96	346.00
IUUC-Gac-041944	Gasterosteus aculeatus	81.74	6.00e-162	563.00
IUUC-Loc-052858	Lepisosteus oculatus	59.65	0.00e+00	725.00
IUUC-Mtr-058075	Medicago truncatula	33.64	2.00e-44	173.00
IUUC-Ont-072148	Oreochromis niloticus	54.46	8.00e-179	620.00
IUUC-Ola-087198	Oryzias latipes	83.12	2.00e-158	551.00
IUUC-Olu-087810	Ostreococcus lucimarinus	22.80	2.00e-06	47.80
IUUC-Psi-093395	Pelodiscus sinensis	66.21	1.00e-105	376.00
IUUC-Pfo-096795	Poecilia formosa	81.16	9.00e-163	566.00
IUUC-Sly-111396	Solanum lycopersicum	33.96	5.00e-41	161.00
IUUC-Tgu-117490	Taeniopygia guttata	65.77	6.00e-116	410.00
IUUC-Tni-120476	Tetraodon nigroviridis	94.97	2.00e-169	587.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence