iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069519

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01079366

Gene Name

OTUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000004735.1	ENSNLET00000006083.1	ENSNLEP00000005780.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	2.50e-43	147.8	189	311

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 20   s........llgvfdddslsdalveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvd 99
                    ll++f+d+s+sd+lv++Lr+lts ylq+es+ff++fie+++++kefcq++vep++k +++ihi+aLaq+Ls++i+v+++d
   Q: 189  VekqtsvadLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKeSDHIHIIALAQALSVSIQVEYMD 277
           15556666689****************************************************************************** PP
   S: 100  sleskvggillpllfpeeklkkpivLlYrsgHYdaLva 137
           ++e   gg+++p++fpe + +++++LlYr+gHYd+L++
   Q: 278  RGE---GGTTNPHIFPEGS-EPKVYLLYRPGHYDILYK 311
           **9...9************.****************96 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MMKPSWLSRT EFSKRLLCRT LWCQSGWSSR SYTRSMLKMT TSINRRSRTS TKSTRTSARP 60
GLTATVSIGL SDSPTWRHCW MTARSCSGEK GGHWAPRQVG VSLLPGRVGG AAPPEAGDGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGTGTTAAC TGTCTGGCCT ATGATGAAGC CATCATGGCT CAGCAGGACC GAATTCAGCA 60
AGAGGTGAGG GGCTGCAGTG GGTGAGGGAG GCAGTGGCCA GCAGCCCCAT TGTGGAAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030298--OTUB1
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0019784--F:NEDD8-specific protease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006974--P:cellular response to DNA damage stimulus
GO:2000780--P:negative regulation of double-strand break repair
GO:1901315--P:negative regulation of histone H2A K63-linked ubiquitination
GO:0071108--P:protein K48-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001871	Ailuropoda melanoleuca	88.17	1.00e-93	335.00
IUUC-Apl-003233	Anas platyrhynchos	58.46	1.00e-18	83.60
IUUC-Aca-004648	Anolis carolinensis	77.78	4.00e-82	297.00
IUUC-Afl-008439	Aspergillus flavus	34.18	2.00e-08	52.80
IUUC-Ame-010662	Astyanax mexicanus	81.99	1.00e-78	286.00
IUUC-Bta-013533	Bos taurus	86.56	2.00e-92	332.00
IUUC-Cja-019190	Callithrix jacchus	88.17	7.00e-94	336.00
IUUC-Cfa-020430	Canis familiaris	88.17	9.00e-94	336.00
IUUC-Cpo-022355	Cavia porcellus	87.63	5.00e-94	337.00
IUUC-Csa-023286	Chlorocebus sabaeus	88.17	6.00e-94	336.00
IUUC-Dre-027843	Danio rerio	75.27	8.00e-81	293.00
IUUC-Dno-029165	Dasypus novemcinctus	88.17	1.00e-93	335.00
IUUC-Dor-030943	Dipodomys ordii	87.63	5.00e-94	337.00
IUUC-Dme-031922	Drosophila melanogaster	58.90	9.00e-52	196.00
IUUC-Ete-032296	Echinops telfairi	80.54	2.00e-114	405.00
IUUC-Eca-033695	Equus caballus	86.56	6.00e-92	329.00
IUUC-Fca-036441	Felis catus	88.17	1.00e-93	335.00
IUUC-Gmo-038908	Gadus morhua	72.04	9.00e-77	279.00
IUUC-Ggr-040020	Gaeumannomyces graminis	33.75	1.00e-19	91.30
IUUC-Gga-040460	Gallus gallus	68.82	3.00e-74	271.00
IUUC-Gac-042417	Gasterosteus aculeatus	71.51	6.00e-77	280.00
IUUC-Ggo-044552	Gorilla gorilla	93.75	5.00e-142	496.00
IUUC-Hsa-046766	Homo sapiens	88.17	3.00e-94	337.00
IUUC-Itr-048312	Ictidomys tridecemlineatus	87.63	5.00e-94	337.00
IUUC-Lch-050602	Latimeria chalumnae	88.06	5.00e-68	250.00
IUUC-Laf-053705	Loxodonta africana	87.63	5.00e-94	337.00
IUUC-Mcc-055745	Macaca mulatta	88.17	4.00e-93	334.00
IUUC-Meu-056569	Macropus eugenii	86.02	2.00e-92	331.00
IUUC-Mmr-061123	Microcebus murinus	84.35	1.00e-66	246.00
IUUC-Mdo-062613	Monodelphis domestica	86.34	3.00e-65	241.00
IUUC-Mmu-063658	Mus musculus	87.63	5.00e-94	337.00
IUUC-Mpu-066172	Mustela putorius furo	88.17	3.00e-94	337.00
IUUC-Mlu-066966	Myotis lucifugus	87.63	1.00e-93	335.00
IUUC-Ont-071901	Oreochromis niloticus	71.51	4.00e-77	281.00
IUUC-Ola-087331	Oryzias latipes	79.50	1.00e-76	278.00
IUUC-Oga-088064	Otolemur garnettii	88.17	3.00e-94	337.00
IUUC-Oar-089251	Ovis aries	86.56	2.00e-91	328.00
IUUC-Ptr-091430	Pan troglodytes	88.17	8.00e-94	336.00
IUUC-Psi-093823	Pelodiscus sinensis	76.19	7.00e-80	290.00
IUUC-Pma-094366	Petromyzon marinus	71.43	1.00e-76	278.00
IUUC-Pfo-096734	Poecilia formosa	70.43	2.00e-75	275.00
IUUC-Pab-097919	Pongo abelii	85.03	5.00e-67	247.00
IUUC-Pva-102499	Pteropus vampyrus	88.17	4.00e-94	337.00
IUUC-Rno-105233	Rattus norvegicus	87.63	5.00e-94	337.00
IUUC-Sha-107081	Sarcophilus harrisii	86.56	6.00e-92	330.00
IUUC-Ssc-116202	Sus scrofa	88.17	3.00e-94	337.00
IUUC-Tru-117664	Takifugu rubripes	78.26	2.00e-75	275.00
IUUC-Tbe-128116	Tupaia belangeri	79.31	1.00e-141	495.00
IUUC-Ttr-128622	Tursiops truncatus	88.17	5.00e-94	337.00
IUUC-Vvi-131389	Vitis vinifera	42.47	1.00e-32	133.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence