iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033825

UUCD1 version

UUC-EqC-00907

Ensembl Protein ID

ENSECAP00000000891.1

UniProt Accession

F7DR25; F7DR25_HORSE

Protein Name

Uncharacterized protein

Gene Name

SOCS6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000001194.1	ENSECAT00000001123.1	ENSECAP00000000891.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	9.90e-17	60.7	490	535

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
           + +++ ++rSLq+LCR++Ir++++++ +   +kLPLP+++kdYL++++y
   Q: 490  PVSRFMQVRSLQYLCRFVIRQYTRIDLI---QKLPLPNKMKDYLQEKHY 535
           567999*******************888...***************997 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MKKISLKTFR KSFNLNKSKE ETDFMVVQQP SLASDFGKDD SLFGSCYGKD MASCDINSED 60
EKGGKNRSKS ESLMGTLKRR LSAKQKQKGK GSTASGSSAD EDTFSSSSAP IVFKDVRAQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAATGGCT CCAAAGGGTA AATGAAGCTG GAAAAATACA TAGATGCAGC ATTGCAGCCT 60
CTCCAGATGT TTGAGAATAA TATTTCAGAG AGAAATTGAT CCCCTTGGAT TAGGTAACTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028421--SOCS6
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0001772--C:immunological synapse
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0050868--P:negative regulation of T cell activation
GO:0010498--P:proteasomal protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0040008--P:regulation of growth

KEGG

ecb:100052089

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001911	Ailuropoda melanoleuca	96.82	0.00e+00	939.00
IUUC-Apl-004035	Anas platyrhynchos	91.40	0.00e+00	885.00
IUUC-Aca-004782	Anolis carolinensis	88.43	0.00e+00	840.00
IUUC-Ame-011790	Astyanax mexicanus	70.95	0.00e+00	642.00
IUUC-Bta-012579	Bos taurus	94.74	1.00e-108	386.00
IUUC-Bol-015843	Brassica oleracea	30.14	3.00e-03	36.20
IUUC-Cel-018643	Caenorhabditis elegans	33.59	1.00e-11	62.80
IUUC-Cja-019528	Callithrix jacchus	95.33	0.00e+00	979.00
IUUC-Cfa-020678	Canis familiaris	95.89	0.00e+00	957.00
IUUC-Cpo-021947	Cavia porcellus	95.70	0.00e+00	987.00
IUUC-Csa-023935	Chlorocebus sabaeus	95.33	0.00e+00	952.00
IUUC-Cho-024477	Choloepus hoffmanni	91.96	0.00e+00	943.00
IUUC-Cin-025413	Ciona intestinalis	68.82	3.00e-67	248.00
IUUC-Csv-026247	Ciona savignyi	67.47	3.00e-65	242.00
IUUC-Dre-027636	Danio rerio	69.78	0.00e+00	639.00
IUUC-Dno-029048	Dasypus novemcinctus	94.58	0.00e+00	942.00
IUUC-Dor-030401	Dipodomys ordii	91.79	0.00e+00	910.00
IUUC-Ete-033116	Echinops telfairi	50.18	2.00e-59	222.00
IUUC-Fca-036253	Felis catus	95.14	0.00e+00	880.00
IUUC-Fal-037614	Ficedula albicollis	91.59	0.00e+00	886.00
IUUC-Fox-037898	Fusarium oxysporum	28.33	2.20e-01	29.30
IUUC-Gmo-038928	Gadus morhua	69.00	0.00e+00	659.00
IUUC-Gga-040177	Gallus gallus	90.84	0.00e+00	879.00
IUUC-Gac-042263	Gasterosteus aculeatus	71.03	0.00e+00	691.00
IUUC-Ggo-045288	Gorilla gorilla	95.14	0.00e+00	953.00
IUUC-Hsa-046409	Homo sapiens	95.51	0.00e+00	955.00
IUUC-Itr-048996	Ictidomys tridecemlineatus	94.58	0.00e+00	923.00
IUUC-Lch-050354	Latimeria chalumnae	85.07	0.00e+00	862.00
IUUC-Loc-052319	Lepisosteus oculatus	82.09	0.00e+00	805.00
IUUC-Laf-054070	Loxodonta africana	92.15	0.00e+00	891.00
IUUC-Mcc-055045	Macaca mulatta	94.95	0.00e+00	948.00
IUUC-Meu-055917	Macropus eugenii	91.40	0.00e+00	946.00
IUUC-Mga-059273	Meleagris gallopavo	91.21	0.00e+00	880.00
IUUC-Mmr-061597	Microcebus murinus	95.51	0.00e+00	951.00
IUUC-Mdo-062492	Monodelphis domestica	67.64	1.00e-110	392.00
IUUC-Mmu-063374	Mus musculus	84.01	0.00e+00	832.00
IUUC-Mpu-065967	Mustela putorius furo	90.84	0.00e+00	892.00
IUUC-Mlu-067532	Myotis lucifugus	94.95	0.00e+00	922.00
IUUC-Nle-069373	Nomascus leucogenys	95.70	0.00e+00	955.00
IUUC-Opr-070873	Ochotona princeps	91.21	0.00e+00	946.00
IUUC-Ont-072498	Oreochromis niloticus	72.74	0.00e+00	721.00
IUUC-Oan-072943	Ornithorhynchus anatinus	73.06	2.00e-98	352.00
IUUC-Ocu-073870	Oryctolagus cuniculus	94.21	0.00e+00	937.00
IUUC-Ola-086866	Oryzias latipes	89.77	1.00e-104	371.00
IUUC-Oga-089057	Otolemur garnettii	91.96	0.00e+00	904.00
IUUC-Oar-089841	Ovis aries	62.13	1.00e-166	579.00
IUUC-Ptr-091054	Pan troglodytes	95.51	0.00e+00	954.00
IUUC-Pma-094253	Petromyzon marinus	82.11	2.00e-92	333.00
IUUC-Pfo-097179	Poecilia formosa	65.99	2.00e-175	608.00
IUUC-Pab-097702	Pongo abelii	95.70	0.00e+00	956.00
IUUC-Pca-100671	Procavia capensis	86.99	5.00e-124	437.00
IUUC-Rno-106044	Rattus norvegicus	81.16	0.00e+00	818.00
IUUC-Sha-107139	Sarcophilus harrisii	90.76	0.00e+00	868.00
IUUC-Smo-108823	Selaginella moellendorffii	33.96	3.60e-02	32.00
IUUC-Ssc-115343	Sus scrofa	93.27	0.00e+00	936.00
IUUC-Tgu-117061	Taeniopygia guttata	91.40	0.00e+00	886.00
IUUC-Tni-119829	Tetraodon nigroviridis	68.63	0.00e+00	634.00
IUUC-Tae-123723	Triticum aestivum	26.25	1.10e-01	32.00
IUUC-Ttr-129148	Tursiops truncatus	92.34	0.00e+00	880.00
IUUC-Vpa-130780	Vicugna pacos	90.47	0.00e+00	853.00
IUUC-Vvi-130966	Vitis vinifera	32.69	5.70e-02	31.20
IUUC-Xtr-132513	Xenopus tropicalis	83.36	0.00e+00	839.00
IUUC-Xma-133904	Xiphophorus maculatus	70.11	0.00e+00	659.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence