iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
            ++ +++ ++rSLq+LCR++Ir++++++ +   +kLPLP+++kdYL++++y
   Q: 500  TNPVSRFMQVRSLQYLCRFVIRQYTRIDLI---QKLPLPNKMKDYLQEKHY 547
           5788999********************888...***************997 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MKKISLKTFR KSFNLSKSKD ETEFMVVQPQ SLAGDFVKDD SLFGSCYGKD MASCDIGSED 60
EKGKNRSKSE SLMGTLKRRL SAKQKTKGKG GTAPTDEDAF SSASAPGGLK DVRAPRPIRS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTTTTCATT TTGTCTGGGG AAATGGTAGC ATGCTGGTCA GATTTTTGTC AACTGGACAT 60
AAGCTACAGT TATTTGGGAA GAGGAACTCT AAATTGAGAA AATGCCTCCA TAAGATTTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028421--SOCS6
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0001772--C:immunological synapse
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0050868--P:negative regulation of T cell activation
GO:0010498--P:proteasomal protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0040008--P:regulation of growth

KEGG

rno:307200

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001911	Ailuropoda melanoleuca	80.07	0.00e+00	796.00
IUUC-Atr-002940	Amborella trichopoda	32.50	1.50e-02	33.90
IUUC-Apl-004035	Anas platyrhynchos	77.54	0.00e+00	759.00
IUUC-Aca-004782	Anolis carolinensis	75.77	0.00e+00	742.00
IUUC-Ame-011790	Astyanax mexicanus	62.59	3.00e-162	565.00
IUUC-Bta-012579	Bos taurus	95.69	4.00e-109	388.00
IUUC-Bol-015843	Brassica oleracea	28.77	4.30e-02	32.70
IUUC-Cel-018643	Caenorhabditis elegans	33.59	2.00e-11	62.40
IUUC-Cja-019528	Callithrix jacchus	82.07	0.00e+00	840.00
IUUC-Cfa-020678	Canis familiaris	80.98	0.00e+00	817.00
IUUC-Cpo-021947	Cavia porcellus	80.80	0.00e+00	838.00
IUUC-Csa-023935	Chlorocebus sabaeus	81.70	0.00e+00	823.00
IUUC-Cho-024477	Choloepus hoffmanni	78.99	0.00e+00	811.00
IUUC-Cin-025413	Ciona intestinalis	68.24	4.00e-66	244.00
IUUC-Csv-026247	Ciona savignyi	67.47	1.00e-64	240.00
IUUC-Dre-027636	Danio rerio	63.08	2.00e-163	569.00
IUUC-Dno-029048	Dasypus novemcinctus	79.39	0.00e+00	811.00
IUUC-Dor-030401	Dipodomys ordii	79.53	0.00e+00	800.00
IUUC-Ete-033116	Echinops telfairi	47.52	4.00e-55	208.00
IUUC-Eca-033825	Equus caballus	79.71	0.00e+00	787.00
IUUC-Fca-036253	Felis catus	76.25	0.00e+00	737.00
IUUC-Fal-037614	Ficedula albicollis	77.72	0.00e+00	760.00
IUUC-Fox-037898	Fusarium oxysporum	24.49	3.20e-01	28.90
IUUC-Gmo-038928	Gadus morhua	64.22	2.00e-173	602.00
IUUC-Gga-040177	Gallus gallus	77.17	0.00e+00	756.00
IUUC-Gac-042263	Gasterosteus aculeatus	64.58	7.00e-180	623.00
IUUC-Ggo-045288	Gorilla gorilla	81.34	0.00e+00	822.00
IUUC-Hsa-046409	Homo sapiens	81.52	0.00e+00	822.00
IUUC-Itr-048996	Ictidomys tridecemlineatus	80.07	0.00e+00	786.00
IUUC-Lch-050354	Latimeria chalumnae	73.06	0.00e+00	758.00
IUUC-Loc-052319	Lepisosteus oculatus	71.43	0.00e+00	720.00
IUUC-Laf-054070	Loxodonta africana	78.48	0.00e+00	776.00
IUUC-Mcc-055045	Macaca mulatta	81.88	0.00e+00	826.00
IUUC-Meu-055917	Macropus eugenii	77.90	0.00e+00	814.00
IUUC-Mga-059273	Meleagris gallopavo	77.54	0.00e+00	754.00
IUUC-Mmr-061597	Microcebus murinus	81.16	0.00e+00	816.00
IUUC-Mdo-062492	Monodelphis domestica	51.40	3.00e-79	288.00
IUUC-Mmu-063374	Mus musculus	96.53	0.00e+00	969.00
IUUC-Mpu-065967	Mustela putorius furo	78.62	0.00e+00	783.00
IUUC-Mlu-067532	Myotis lucifugus	79.53	0.00e+00	802.00
IUUC-Nle-069373	Nomascus leucogenys	81.52	0.00e+00	821.00
IUUC-Opr-070873	Ochotona princeps	80.25	0.00e+00	830.00
IUUC-Ont-072498	Oreochromis niloticus	65.59	0.00e+00	659.00
IUUC-Oan-072943	Ornithorhynchus anatinus	64.83	2.00e-86	312.00
IUUC-Ocu-073870	Oryctolagus cuniculus	80.83	0.00e+00	817.00
IUUC-Ola-086866	Oryzias latipes	90.32	1.00e-104	372.00
IUUC-Oga-089057	Otolemur garnettii	79.71	0.00e+00	794.00
IUUC-Oar-089841	Ovis aries	58.18	7.00e-158	550.00
IUUC-Ptr-091054	Pan troglodytes	81.70	0.00e+00	824.00
IUUC-Pma-094253	Petromyzon marinus	82.11	9.00e-92	330.00
IUUC-Pfo-097179	Poecilia formosa	60.79	2.00e-161	561.00
IUUC-Pab-097702	Pongo abelii	81.52	0.00e+00	821.00
IUUC-Pca-100671	Procavia capensis	67.64	7.00e-98	351.00
IUUC-Sha-107139	Sarcophilus harrisii	76.70	0.00e+00	735.00
IUUC-Smo-108823	Selaginella moellendorffii	33.96	3.30e-02	32.00
IUUC-Sly-111748	Solanum lycopersicum	32.00	6.10e-01	28.90
IUUC-Ssc-115343	Sus scrofa	81.88	0.00e+00	829.00
IUUC-Tgu-117061	Taeniopygia guttata	77.54	0.00e+00	759.00
IUUC-Tni-119829	Tetraodon nigroviridis	60.75	6.00e-167	580.00
IUUC-Ttr-129148	Tursiops truncatus	78.62	0.00e+00	761.00
IUUC-Vpa-130780	Vicugna pacos	78.58	0.00e+00	763.00
IUUC-Vvi-130966	Vitis vinifera	32.69	5.30e-02	31.20
IUUC-Xtr-132513	Xenopus tropicalis	71.87	0.00e+00	727.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence