iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035642

Ensembl Protein ID

ENSFCAP00000025178.1

UniProt Accession

M3XEW9; M3XEW9_FELCA

Genbank Protein ID

ENSFCAP00000025178

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02086516

Gene Name

TRIM13

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000028107.1	ENSFCAT00000031244.1	ENSFCAP00000025178.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.20e-09	36.3	10	58

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw....pglknssskefrCPlCr 46
           C+iC++ f+d p+vlpC H f+++Cl+ +    +  +   s  f+CP+Cr
   Q: 10   CPICCSLFDD-PRVLPCSHNFCKKCLEGIlegtVRNSLWRSSPFKCPTCR 58
           ********99.**************96666777677777**********8 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MELLEEDLTC PICCSLFDDP RVLPCSHNFC KKCLEGILEG TVRNSLWRSS PFKCPTCRKE 60
TSATGVNSLQ VNYSLKGIVE KYNKIKISPK MPVCKGHLGQ PLNIFCLTDM QLICGICATR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCTGC TTGAAGAAGA TCTCACGTGC CCAATTTGTT GCAGTCTGTT TGATGATCCT 60
CGAGTTTTGC CTTGCTCGCA TAACTTTTGC AAAAAATGCT TAGAAGGGAT CTTAGAGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0097038--C:perinuclear endoplasmic reticulum
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010942--P:positive regulation of cell death
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016239--P:positive regulation of macroautophagy
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0051865--P:protein autoubiquitination
GO:0010332--P:response to gamma radiation
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

fca:101093233

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002269	Ailuropoda melanoleuca	97.30	0.00e+00	755.00
IUUC-Apl-004168	Anas platyrhynchos	76.72	0.00e+00	634.00
IUUC-Aca-004395	Anolis carolinensis	70.34	4.00e-168	583.00
IUUC-Ame-011325	Astyanax mexicanus	46.44	3.00e-68	251.00
IUUC-Bta-012613	Bos taurus	93.86	0.00e+00	730.00
IUUC-Cja-018856	Callithrix jacchus	93.37	0.00e+00	791.00
IUUC-Cfa-021019	Canis familiaris	95.58	0.00e+00	744.00
IUUC-Cpo-021845	Cavia porcellus	91.40	0.00e+00	714.00
IUUC-Csa-023380	Chlorocebus sabaeus	92.63	0.00e+00	738.00
IUUC-Cho-024733	Choloepus hoffmanni	83.26	3.00e-89	322.00
IUUC-Dre-028675	Danio rerio	48.42	3.00e-108	385.00
IUUC-Dno-030018	Dasypus novemcinctus	91.67	0.00e+00	736.00
IUUC-Dor-030599	Dipodomys ordii	90.26	3.00e-129	454.00
IUUC-Ete-033134	Echinops telfairi	87.99	0.00e+00	718.00
IUUC-Eca-033931	Equus caballus	96.31	0.00e+00	735.00
IUUC-Eeu-034903	Erinaceus europaeus	92.38	0.00e+00	718.00
IUUC-Fal-037108	Ficedula albicollis	77.45	0.00e+00	648.00
IUUC-Gga-040903	Gallus gallus	75.75	0.00e+00	632.00
IUUC-Ggo-044635	Gorilla gorilla	93.12	0.00e+00	741.00
IUUC-Hsa-046345	Homo sapiens	92.87	0.00e+00	739.00
IUUC-Itr-048220	Ictidomys tridecemlineatus	90.98	0.00e+00	696.00
IUUC-Lch-050599	Latimeria chalumnae	61.19	7.00e-139	486.00
IUUC-Loc-052378	Lepisosteus oculatus	63.07	3.00e-117	414.00
IUUC-Laf-053332	Loxodonta africana	92.16	0.00e+00	721.00
IUUC-Mcc-054705	Macaca mulatta	92.38	0.00e+00	736.00
IUUC-Meu-056825	Macropus eugenii	85.05	0.00e+00	719.00
IUUC-Mga-059528	Meleagris gallopavo	75.74	0.00e+00	643.00
IUUC-Mmr-060688	Microcebus murinus	94.84	0.00e+00	733.00
IUUC-Mdo-061882	Monodelphis domestica	83.82	0.00e+00	718.00
IUUC-Mmu-064352	Mus musculus	89.19	0.00e+00	739.00
IUUC-Mpu-066712	Mustela putorius furo	96.83	0.00e+00	694.00
IUUC-Mlu-068093	Myotis lucifugus	94.35	0.00e+00	728.00
IUUC-Nle-069310	Nomascus leucogenys	93.12	0.00e+00	738.00
IUUC-Ont-071759	Oreochromis niloticus	59.28	8.00e-111	393.00
IUUC-Oan-073673	Ornithorhynchus anatinus	80.64	0.00e+00	694.00
IUUC-Ocu-074192	Oryctolagus cuniculus	92.63	0.00e+00	732.00
IUUC-Ola-087424	Oryzias latipes	58.96	4.00e-109	387.00
IUUC-Oga-088808	Otolemur garnettii	93.86	0.00e+00	737.00
IUUC-Oar-089553	Ovis aries	94.10	0.00e+00	732.00
IUUC-Ptr-090518	Pan troglodytes	92.63	0.00e+00	736.00
IUUC-Pan-092781	Papio anubis	92.38	0.00e+00	735.00
IUUC-Psi-093914	Pelodiscus sinensis	75.79	0.00e+00	636.00
IUUC-Pfo-096346	Poecilia formosa	56.55	8.00e-110	390.00
IUUC-Pca-100914	Procavia capensis	89.95	0.00e+00	732.00
IUUC-Pva-102728	Pteropus vampyrus	95.09	0.00e+00	733.00
IUUC-Rno-105922	Rattus norvegicus	88.94	0.00e+00	684.00
IUUC-Sha-107124	Sarcophilus harrisii	84.80	0.00e+00	728.00
IUUC-Sar-113607	Sorex araneus	90.66	0.00e+00	700.00
IUUC-Ssc-116355	Sus scrofa	95.82	0.00e+00	743.00
IUUC-Tgu-116476	Taeniopygia guttata	76.94	0.00e+00	646.00
IUUC-Tru-118737	Takifugu rubripes	59.93	6.00e-113	400.00
IUUC-Tsy-118908	Tarsius syrichta	94.35	0.00e+00	755.00
IUUC-Tbe-127258	Tupaia belangeri	96.31	0.00e+00	743.00
IUUC-Vpa-130138	Vicugna pacos	94.10	0.00e+00	737.00
IUUC-Xtr-132100	Xenopus tropicalis	58.84	7.00e-133	466.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence