iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-002237

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

E3 ubiquitin-protein ligase RNF146

Genbank Nucleotide ID

ACTA01066556

Gene Name

RNF146

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000020158.1	ENSAMET00000021981.1	ENSAMEP00000021212.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.36	2.00e-153	540.00	IUUC-Hsa-045790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

RMAGCGEIDH SVNMLPTNRK ANESCANPAP SLTVPECAIC LQTCVHPVSL PCKHVFCYLC 60
VKGASWLGKR CALCRQEIPE DFLDKPTLLS PEELKAASRG NGEYAWYYEG RNGWWQYDER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGATGGCTG GCTGTGGTGA AATTGATCAC TCAGTAAACA TGCTTCCTAC GAACAGGAAA 60
GCGAATGAGT CCTGTGCGAA TCCTGCACCT TCTCTAACTG TCCCTGAATG TGCCATTTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033509--RNF146
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50918--WWE
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02825--WWE

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0072572--F:poly-ADP-D-ribose binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004143	Anas platyrhynchos	86.43	3.00e-136	478.00
IUUC-Aca-004557	Anolis carolinensis	81.22	2.00e-129	454.00
IUUC-Ame-011088	Astyanax mexicanus	60.85	2.00e-83	302.00
IUUC-Bta-012639	Bos taurus	91.64	3.00e-150	524.00
IUUC-Cel-018462	Caenorhabditis elegans	28.35	5.00e-19	87.40
IUUC-Cja-019397	Callithrix jacchus	95.54	2.00e-159	555.00
IUUC-Cfa-021140	Canis familiaris	92.76	7.00e-167	579.00
IUUC-Cpo-021387	Cavia porcellus	88.89	2.00e-165	574.00
IUUC-Csa-023503	Chlorocebus sabaeus	91.41	7.00e-154	536.00
IUUC-Cho-024895	Choloepus hoffmanni	91.80	1.00e-140	492.00
IUUC-Cin-025455	Ciona intestinalis	52.56	3.00e-43	167.00
IUUC-Dre-028824	Danio rerio	47.30	5.00e-84	304.00
IUUC-Dno-029269	Dasypus novemcinctus	93.91	1.00e-159	555.00
IUUC-Dor-030592	Dipodomys ordii	91.64	9.00e-162	562.00
IUUC-Dme-031618	Drosophila melanogaster	55.49	2.00e-56	213.00
IUUC-Ete-032478	Echinops telfairi	91.67	3.00e-161	560.00
IUUC-Eca-033389	Equus caballus	95.26	1.00e-178	619.00
IUUC-Fca-035488	Felis catus	95.56	4.00e-162	563.00
IUUC-Fal-037087	Ficedula albicollis	83.98	2.00e-153	535.00
IUUC-Gmo-039713	Gadus morhua	36.62	6.00e-08	55.50
IUUC-Gga-040401	Gallus gallus	86.70	1.00e-138	486.00
IUUC-Gac-042412	Gasterosteus aculeatus	64.66	1.00e-87	316.00
IUUC-Ggo-045417	Gorilla gorilla	95.34	5.00e-152	530.00
IUUC-Hsa-045790	Homo sapiens	95.26	6.00e-159	553.00
IUUC-Itr-048820	Ictidomys tridecemlineatus	92.50	3.00e-163	567.00
IUUC-Lch-049493	Latimeria chalumnae	69.53	9.00e-111	393.00
IUUC-Loc-052927	Lepisosteus oculatus	66.20	2.00e-101	361.00
IUUC-Laf-053904	Loxodonta africana	93.07	1.00e-159	555.00
IUUC-Mcc-055427	Macaca mulatta	91.39	6.00e-159	553.00
IUUC-Mmr-060580	Microcebus murinus	93.35	3.00e-154	537.00
IUUC-Mdo-062094	Monodelphis domestica	95.42	3.00e-77	279.00
IUUC-Mmu-063363	Mus musculus	90.25	4.00e-162	563.00
IUUC-Mpu-066816	Mustela putorius furo	96.67	2.00e-163	568.00
IUUC-Mlu-067433	Myotis lucifugus	94.74	6.00e-179	619.00
IUUC-Nle-068986	Nomascus leucogenys	94.99	1.00e-172	598.00
IUUC-Ont-072670	Oreochromis niloticus	66.08	2.00e-81	295.00
IUUC-Oan-073330	Ornithorhynchus anatinus	88.56	2.00e-107	381.00
IUUC-Ocu-074161	Oryctolagus cuniculus	90.53	1.00e-160	558.00
IUUC-Ola-086902	Oryzias latipes	60.14	2.00e-85	308.00
IUUC-Oga-089159	Otolemur garnettii	93.04	1.00e-180	625.00
IUUC-Oar-089586	Ovis aries	92.48	5.00e-145	506.00
IUUC-Ptr-090987	Pan troglodytes	95.26	6.00e-159	553.00
IUUC-Pan-091867	Papio anubis	91.41	2.00e-159	555.00
IUUC-Psi-094024	Pelodiscus sinensis	85.08	1.00e-141	495.00
IUUC-Pma-094453	Petromyzon marinus	63.91	5.00e-65	241.00
IUUC-Pfo-097108	Poecilia formosa	56.00	7.00e-84	303.00
IUUC-Pab-097997	Pongo abelii	93.87	2.00e-165	574.00
IUUC-Pca-100260	Procavia capensis	90.81	2.00e-161	561.00
IUUC-Pva-103140	Pteropus vampyrus	93.89	8.00e-163	566.00
IUUC-Rno-105795	Rattus norvegicus	84.40	2.00e-158	551.00
IUUC-Sha-107033	Sarcophilus harrisii	87.85	2.00e-154	538.00
IUUC-Ssc-116395	Sus scrofa	95.01	1.00e-177	615.00
IUUC-Tgu-116685	Taeniopygia guttata	82.04	4.00e-135	474.00
IUUC-Tru-118014	Takifugu rubripes	75.36	3.00e-84	304.00
IUUC-Tsy-119326	Tarsius syrichta	87.22	8.00e-170	589.00
IUUC-Tni-120322	Tetraodon nigroviridis	69.95	2.00e-82	299.00
IUUC-Tbe-128067	Tupaia belangeri	93.06	5.00e-166	576.00
IUUC-Ttr-128530	Tursiops truncatus	95.56	1.00e-162	565.00
IUUC-Vpa-130322	Vicugna pacos	96.38	2.00e-168	584.00
IUUC-Xtr-132606	Xenopus tropicalis	66.67	9.00e-119	419.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence