iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027493

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ring finger protein 145a

Genbank Nucleotide ID

CU019638

Gene Name

rnf145a

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000002609.10	ENSDART00000004550.10	ENSDARP00000002111.8

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.40e-09	36.6	537	574

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           C+iC++d+    +++pC H+fha Cl+kw       + + +CPlC
   Q: 537  CSICYQDMTS-AVITPCSHLFHAGCLKKW------LYVQETCPLC 574
           ********99.888***************......********** PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MAVKERVEAV LNVGLRVPSI MLLEVLYRWD VSSFFQKIQR SSLNNNPLFQ YKYLALYLHY 60
VGYILSLVLL TLPRQHLVQL YLYVLTALLL FAGHQISRDY VRSELESGYE GPLYLEPLSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTGGCGAT CTGTAATGGC TGCGGGATGA TGTGATACGA GTCCCGGTGC CGAGCCGCGT 60
CTCTTCGGTA GGAATGCCTT TTCCTTGAGA CCGCCAACCA CTCCGTTCAT TCCTCCGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025754--TRC8_N_dom
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13705--TRC8_N
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

dre:565986

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002354	Ailuropoda melanoleuca	83.28	0.00e+00	1004.00
IUUC-Bta-012560	Bos taurus	82.64	0.00e+00	1006.00
IUUC-Cel-018539	Caenorhabditis elegans	29.24	1.00e-65	244.00
IUUC-Cfa-021110	Canis familiaris	82.49	0.00e+00	1003.00
IUUC-Cpo-022452	Cavia porcellus	81.97	0.00e+00	993.00
IUUC-Dse-031284	Dothistroma septosporum	46.51	6.00e-09	54.70
IUUC-Fca-035696	Felis catus	83.31	0.00e+00	1000.00
IUUC-Gac-041731	Gasterosteus aculeatus	88.18	0.00e+00	1066.00
IUUC-Lch-050499	Latimeria chalumnae	86.06	0.00e+00	996.00
IUUC-Loc-052482	Lepisosteus oculatus	89.79	0.00e+00	1038.00
IUUC-Laf-053362	Loxodonta africana	82.28	0.00e+00	1001.00
IUUC-Meu-056130	Macropus eugenii	71.99	1.00e-119	423.00
IUUC-Mmr-060812	Microcebus murinus	83.07	0.00e+00	996.00
IUUC-Mdo-063045	Monodelphis domestica	89.18	0.00e+00	990.00
IUUC-Mpu-066637	Mustela putorius furo	83.78	0.00e+00	1004.00
IUUC-Opr-070210	Ochotona princeps	68.88	1.00e-101	363.00
IUUC-Oan-073730	Ornithorhynchus anatinus	82.64	0.00e+00	999.00
IUUC-Ola-087368	Oryzias latipes	93.44	0.00e+00	1057.00
IUUC-Oga-088301	Otolemur garnettii	83.31	0.00e+00	979.00
IUUC-Oar-089745	Ovis aries	82.01	0.00e+00	1005.00
IUUC-Pva-102485	Pteropus vampyrus	82.36	0.00e+00	954.00
IUUC-Tsy-119541	Tarsius syrichta	82.78	0.00e+00	981.00
IUUC-Xtr-132826	Xenopus tropicalis	89.12	0.00e+00	1023.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence