iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096232

Ensembl Protein ID

ENSPFOP00000010310.1

UniProt Accession

A0A087XX07; A0A087XX07_POEFO

Genbank Protein ID

ENSPFOP00000010310

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01006671

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000010355.1	ENSPFOT00000010325.1	ENSPFOP00000010310.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.30e-120	403.4	4195	4529
UBD/Alpha-Helix/UBA	3.70e-06	27.5	1399	1436

Active Site

Position(s)	Description	Evidence
4497	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrll 88
           ++d+k+rl++ f+gEeg+d+gG+ re++  +s+e++np++ lf++s++d+ t+++np+s + np+hl++F+f+Gr+++ka++d+rll
   Q: 4195 PEDMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHC-NPNHLSYFKFVGRVVAKAVYDNRLL 4280
           689********************************************************86.99*********************** PP
   S: 89   dlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvk 175
           ++ +++sfyk++lgk++ + d+e+ d  +++ l +++en   d+++lg +ltfs++ +++g +++++Lkp+G+ni Vt+eNk+eYv+
   Q: 4281 ECYFTRSFYKHILGKSVRYTDMESEDYPFFQGLVYLLEN---DVSTLGYELTFSTEVQEFGVCEVRDLKPNGANIIVTEENKKEYVH 4364
           *************************************99...********************************************* PP
   S: 176  lvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerk 262
           lv++++++  i++q++af eGf+e+ip++l+s+Fte+elelli+G ++id++dlk++t+y++ y+++s +iqwFw++l++f++ +r+
   Q: 4365 LVCQMKMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELLISGLPTIDIDDLKANTEYHK-YQSSSIQIQWFWRALRSFDQADRA 4450
           ************************************************************66.************************ PP
   S: 263  afLqFvTgssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           +fLqFvTg+s++Pl+Gfa+l+     ++f+i++ d+s+drlPs++TCfn+L+LP Y+s+e+l+++Ll+Ai+e+ +gF+l
   Q: 4451 KFLQFVTGTSKVPLQGFAALEgmngIQKFQIHRdDRSTDRLPSAHTCFNQLDLPAYESYEKLRHMLLLAIQECsEGFGL 4529
           *********************99998999999988899***************************************97 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLldg 41
           ++ +l ql++MGF+re+a +aL++   + e A+eyLl++
   Q: 1399 NQAQLTQLMDMGFSREHAMEALLN-TSTMEQATEYLLTH 1436
           67899*******************.7***********98 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MKVDRSKLKK TPTEAPADCR ILIEKLKACH DEQLLVELQQ IKTWNIGKCE LYHWVDLLDR 60
FDGILCDAGQ TVENMSWLLV CDRPDNGQLK ALLLAVLNFT ALLIEYSFSR HLYSSIEHLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCGTGTAAA GGAAATCAAA AGCAAACAAA TGGAAGAATG GTGATGCTGA TGAACCAAAG 60
CATTTTCTGG TATGTACCTT GAGCATCTTT TGCACTCTTT TCCAAGGCAT TCATGGTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr

PROSITE

PS50237--HECT
PS50030--UBA
PS50918--WWE

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA
PF02825--WWE

SMART

SM00119--HECTc
SM00165--UBA
SM00678--WWE

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	46.95	9.00e-107	384.00
IUUC-Aml-001684	Ailuropoda melanoleuca	81.86	0.00e+00	3661.00
IUUC-Atr-002582	Amborella trichopoda	51.99	2.00e-126	449.00
IUUC-Apl-003729	Anas platyrhynchos	91.29	0.00e+00	684.00
IUUC-Aca-005263	Anolis carolinensis	81.24	0.00e+00	3670.00
IUUC-Aly-006083	Arabidopsis lyrata	51.77	2.00e-126	449.00
IUUC-Ath-007472	Arabidopsis thaliana	51.77	1.00e-126	449.00
IUUC-Ago-008005	Ashbya gossypii	47.79	9.00e-132	466.00
IUUC-Acl-008254	Aspergillus clavatus	53.43	5.00e-134	474.00
IUUC-Afl-008712	Aspergillus flavus	46.56	3.00e-135	476.00
IUUC-Afu-009022	Aspergillus fumigatus	46.37	9.00e-134	473.00
IUUC-Ani-009412	Aspergillus nidulans	47.33	1.00e-135	479.00
IUUC-Ang-009771	Aspergillus niger	46.37	1.00e-134	476.00
IUUC-Aor-010186	Aspergillus oryzae	45.84	2.00e-125	444.00
IUUC-Ate-010253	Aspergillus terreus	46.65	1.00e-134	476.00
IUUC-Ame-011067	Astyanax mexicanus	87.58	0.00e+00	5160.00
IUUC-Bgr-012043	Blumeria graminis	47.61	3.00e-139	491.00
IUUC-Bta-012813	Bos taurus	81.67	0.00e+00	3696.00
IUUC-Bci-013995	Botrytis cinerea	46.65	1.00e-137	486.00
IUUC-Bdi-014884	Brachypodium distachyon	51.99	2.00e-127	452.00
IUUC-Bol-016533	Brassica oleracea	57.97	6.00e-89	320.00
IUUC-Bra-016637	Brassica rapa	50.78	1.00e-123	439.00
IUUC-Cel-018179	Caenorhabditis elegans	61.72	0.00e+00	650.00
IUUC-Cja-018741	Callithrix jacchus	81.58	0.00e+00	3669.00
IUUC-Cfa-020083	Canis familiaris	81.93	0.00e+00	3694.00
IUUC-Cpo-021923	Cavia porcellus	81.52	0.00e+00	3649.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	48.72	2.00e-118	419.00
IUUC-Csa-023853	Chlorocebus sabaeus	81.67	0.00e+00	3669.00
IUUC-Cho-024718	Choloepus hoffmanni	97.33	0.00e+00	800.00
IUUC-Cin-025627	Ciona intestinalis	46.28	0.00e+00	1467.00
IUUC-Csv-025824	Ciona savignyi	46.03	0.00e+00	1391.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	52.00	4.00e-136	481.00
IUUC-Cne-027095	Cryptococcus neoformans	41.87	1.00e-103	373.00
IUUC-Cme-027267	Cyanidioschyzon merolae	50.00	2.00e-115	411.00
IUUC-Dre-028525	Danio rerio	88.49	0.00e+00	4813.00
IUUC-Dno-029680	Dasypus novemcinctus	80.74	0.00e+00	3607.00
IUUC-Dor-030902	Dipodomys ordii	84.29	0.00e+00	1069.00
IUUC-Dse-031197	Dothistroma septosporum	46.36	6.00e-137	484.00
IUUC-Dme-032122	Drosophila melanogaster	69.29	0.00e+00	790.00
IUUC-Ete-032690	Echinops telfairi	67.68	0.00e+00	937.00
IUUC-Eca-033915	Equus caballus	81.36	0.00e+00	3632.00
IUUC-Eeu-034963	Erinaceus europaeus	79.06	0.00e+00	2555.00
IUUC-Fca-035824	Felis catus	81.86	0.00e+00	3671.00
IUUC-Fox-037756	Fusarium oxysporum	46.86	6.00e-137	484.00
IUUC-Fso-038464	Fusarium solani	47.71	5.00e-137	484.00
IUUC-Gmo-039073	Gadus morhua	89.93	0.00e+00	3964.00
IUUC-Ggr-039946	Gaeumannomyces graminis	44.75	2.00e-134	476.00
IUUC-Gga-040309	Gallus gallus	96.75	0.00e+00	644.00
IUUC-Gac-042430	Gasterosteus aculeatus	91.15	0.00e+00	4119.00
IUUC-Gma-044247	Glycine max	52.22	3.00e-126	448.00
IUUC-Ggo-044785	Gorilla gorilla	81.49	0.00e+00	3641.00
IUUC-Hsa-046879	Homo sapiens	81.53	0.00e+00	3647.00
IUUC-Hvu-047697	Hordeum vulgare	51.99	1.00e-127	453.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	94.00	0.00e+00	1062.00
IUUC-Kpa-049228	Komagataella pastoris	48.47	7.00e-139	490.00
IUUC-Lch-050252	Latimeria chalumnae	85.21	0.00e+00	1670.00
IUUC-Lpe-051550	Leersia perrieri	51.15	1.00e-127	452.00
IUUC-Loc-052472	Lepisosteus oculatus	85.87	0.00e+00	3768.00
IUUC-Lma-053159	Leptosphaeria maculans	46.37	1.00e-135	479.00
IUUC-Laf-054154	Loxodonta africana	81.18	0.00e+00	3630.00
IUUC-Mcc-055085	Macaca mulatta	81.84	0.00e+00	3661.00
IUUC-Meu-056727	Macropus eugenii	86.14	0.00e+00	1768.00
IUUC-Mor-057201	Magnaporthe oryzae	47.15	2.00e-135	479.00
IUUC-Mpo-057597	Magnaporthe poae	46.11	4.00e-133	471.00
IUUC-Mtr-058273	Medicago truncatula	52.93	6.00e-128	454.00
IUUC-Mla-058888	Melampsora laricipopulina	49.62	1.00e-116	412.00
IUUC-Mvi-060320	Microbotryum violaceum	49.29	6.00e-122	434.00
IUUC-Mmr-060820	Microcebus murinus	81.50	0.00e+00	3659.00
IUUC-Mdo-062930	Monodelphis domestica	81.49	0.00e+00	3674.00
IUUC-Mmu-063601	Mus musculus	86.77	0.00e+00	2211.00
IUUC-Mac-065557	Musa acuminata	52.09	3.00e-119	425.00
IUUC-Mpu-066653	Mustela putorius furo	79.96	0.00e+00	3539.00
IUUC-Mlu-067418	Myotis lucifugus	81.64	0.00e+00	3719.00
IUUC-Nfi-068278	Neosartorya fischeri	46.56	3.00e-134	475.00
IUUC-Ncr-068813	Neurospora crassa	46.95	7.00e-137	484.00
IUUC-Nle-069418	Nomascus leucogenys	81.33	0.00e+00	3622.00
IUUC-Opr-070187	Ochotona princeps	79.58	0.00e+00	846.00
IUUC-Ont-071300	Oreochromis niloticus	90.09	0.00e+00	5448.00
IUUC-Oan-073046	Ornithorhynchus anatinus	72.89	0.00e+00	1977.00
IUUC-Ocu-074178	Oryctolagus cuniculus	81.38	0.00e+00	3696.00
IUUC-Oba-075757	Oryza barthii	51.15	5.00e-128	454.00
IUUC-Obr-076553	Oryza brachyantha	51.61	7.00e-128	453.00
IUUC-Ogl-077520	Oryza glaberrima	51.15	5.00e-128	454.00
IUUC-Ogu-078278	Oryza glumaepatula	51.15	5.00e-128	454.00
IUUC-Oin-079767	Oryza indica	51.15	5.00e-128	454.00
IUUC-Olo-080380	Oryza longistaminata	50.68	4.00e-126	448.00
IUUC-Ome-081925	Oryza meridionalis	50.68	3.00e-126	448.00
IUUC-Oni-082619	Oryza nivara	51.15	6.00e-128	454.00
IUUC-Opu-083684	Oryza punctata	50.68	3.00e-126	448.00
IUUC-Oru-084501	Oryza rufipogon	51.15	5.00e-128	454.00
IUUC-Osa-086251	Oryza sativa	51.15	2.00e-126	446.00
IUUC-Ola-087437	Oryzias latipes	90.67	0.00e+00	2308.00
IUUC-Olu-087813	Ostreococcus lucimarinus	50.25	1.00e-113	403.00
IUUC-Oga-088903	Otolemur garnettii	81.59	0.00e+00	3645.00
IUUC-Oar-090210	Ovis aries	81.95	0.00e+00	3694.00
IUUC-Ptr-090502	Pan troglodytes	80.45	0.00e+00	2735.00
IUUC-Pan-092368	Papio anubis	81.12	0.00e+00	3682.00
IUUC-Pma-094246	Petromyzon marinus	70.64	0.00e+00	1219.00
IUUC-Pno-094871	Phaeosphaeria nodorum	51.12	9.00e-134	473.00
IUUC-Ppa-095657	Physcomitrella patens	51.36	1.00e-125	446.00
IUUC-Pab-098583	Pongo abelii	81.53	0.00e+00	3647.00
IUUC-Pop-099613	Populus trichocarpa	53.40	5.00e-129	457.00
IUUC-Pca-100310	Procavia capensis	72.10	0.00e+00	1448.00
IUUC-Ppe-102109	Prunus persica	52.69	2.00e-127	452.00
IUUC-Pva-102116	Pteropus vampyrus	81.50	0.00e+00	3702.00
IUUC-Pgr-103465	Puccinia graminis	44.34	5.00e-128	454.00
IUUC-Ptt-103813	Puccinia triticina	42.23	1.00e-115	413.00
IUUC-Pte-104018	Pyrenophora teres	51.23	2.00e-132	469.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	51.24	5.00e-132	468.00
IUUC-Rno-105889	Rattus norvegicus	86.77	0.00e+00	2207.00
IUUC-Sce-106449	Saccharomyces cerevisiae	44.75	3.00e-127	451.00
IUUC-Sha-106961	Sarcophilus harrisii	87.09	0.00e+00	2271.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	45.79	4.00e-128	454.00
IUUC-Spo-108024	Schizosaccharomyces pombe	46.64	7.00e-130	460.00
IUUC-Smo-109640	Selaginella moellendorffii	50.77	3.00e-130	461.00
IUUC-Sit-110598	Setaria italica	52.46	6.00e-128	454.00
IUUC-Sly-111285	Solanum lycopersicum	51.89	2.00e-128	456.00
IUUC-Stu-112582	Solanum tuberosum	32.68	4.00e-56	213.00
IUUC-Sar-113291	Sorex araneus	75.54	0.00e+00	2195.00
IUUC-Sbi-114042	Sorghum bicolor	51.99	3.00e-127	451.00
IUUC-Sre-114958	Sporisorium reilianum	56.03	4.00e-138	485.00
IUUC-Ssc-115754	Sus scrofa	81.69	0.00e+00	3662.00
IUUC-Tru-118570	Takifugu rubripes	88.69	0.00e+00	6907.00
IUUC-Tsy-119159	Tarsius syrichta	86.27	0.00e+00	1736.00
IUUC-Tni-120836	Tetraodon nigroviridis	83.12	0.00e+00	2760.00
IUUC-Tca-121479	Theobroma cacao	51.76	1.00e-125	446.00
IUUC-Tre-121909	Trichoderma reesei	53.65	5.00e-134	474.00
IUUC-Tvi-122370	Trichoderma virens	53.41	5.00e-134	474.00
IUUC-Tae-125214	Triticum aestivum	51.04	6.00e-126	446.00
IUUC-Tme-127172	Tuber melanosporum	45.42	1.00e-137	486.00
IUUC-Tbe-127506	Tupaia belangeri	71.24	0.00e+00	1085.00
IUUC-Ttr-129253	Tursiops truncatus	71.11	0.00e+00	1680.00
IUUC-Uma-129355	Ustilago maydis	49.24	7.00e-139	487.00
IUUC-Vda-129886	Verticillium dahliae	47.25	1.00e-138	489.00
IUUC-Vpa-130708	Vicugna pacos	79.60	0.00e+00	3200.00
IUUC-Vvi-131170	Vitis vinifera	51.22	2.00e-127	451.00
IUUC-Xtr-132123	Xenopus tropicalis	68.31	0.00e+00	2155.00
IUUC-Xma-133869	Xiphophorus maculatus	98.57	0.00e+00	7630.00
IUUC-Yli-134657	Yarrowia lipolytica	46.07	2.00e-129	459.00
IUUC-Zma-135570	Zea mays	51.99	1.00e-127	452.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence