iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071711

Ensembl Protein ID

ENSONIP00000010316.1

UniProt Accession

I3JN72; I3JN72_ORENI

Genbank Protein ID

AJB29396.1

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AERX01015096

Gene Name

lck; Lck

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000008194.1	ENSONIT00000010325.1	ENSONIP00000010316.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-13	51.4	58	112

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++v ++y+ye+++d++L + kGd+++++  ++ d +W  +++ ++g++G +P+nFv+
   Q: 58   NVVVAIYSYEPTHDGDLGFDKGDKLKIL--NKDDPEWYLAESLTTGQQGYIPHNFVA 112
           6799************************..8899*********************96 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MGCNCSSDYS DSDWIENLDE ICEHCNCPIP PQSCNPYTDQ LIPYPSQMTP PTSPLPVNVV 60
VAIYSYEPTH DGDLGFDKGD KLKILNKDDP EWYLAESLTT GQQGYIPHNF VALSTVETEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAAGCACCT GTTAAAAGCC TGCAGAGCAA CCCTCAACCT TTCAACGACA GGAAACTCTC 60
TGGGTTGCTC CCCTCCACAG TGCGCATGTG TGCATGCAGG CACCGCATAA GCGCTCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001315	Ailuropoda melanoleuca	65.00	0.00e+00	719.00
IUUC-Apl-004134	Anas platyrhynchos	69.95	0.00e+00	634.00
IUUC-Ame-010831	Astyanax mexicanus	76.36	0.00e+00	710.00
IUUC-Bta-013264	Bos taurus	68.43	0.00e+00	738.00
IUUC-Cfa-021161	Canis familiaris	64.44	0.00e+00	717.00
IUUC-Cpo-022492	Cavia porcellus	68.82	0.00e+00	740.00
IUUC-Dre-028005	Danio rerio	76.15	0.00e+00	789.00
IUUC-Dno-029365	Dasypus novemcinctus	65.88	0.00e+00	691.00
IUUC-Dor-030892	Dipodomys ordii	66.27	0.00e+00	697.00
IUUC-Eca-033325	Equus caballus	66.93	0.00e+00	706.00
IUUC-Eeu-035004	Erinaceus europaeus	60.00	7.00e-157	546.00
IUUC-Fca-035908	Felis catus	68.63	0.00e+00	734.00
IUUC-Gmo-038984	Gadus morhua	77.18	0.00e+00	831.00
IUUC-Gga-040997	Gallus gallus	72.16	0.00e+00	775.00
IUUC-Gac-041854	Gasterosteus aculeatus	88.62	0.00e+00	960.00
IUUC-Ggo-045238	Gorilla gorilla	64.63	0.00e+00	719.00
IUUC-Hsa-047039	Homo sapiens	68.43	0.00e+00	734.00
IUUC-Itr-048479	Ictidomys tridecemlineatus	68.82	0.00e+00	740.00
IUUC-Lch-049568	Latimeria chalumnae	72.96	0.00e+00	786.00
IUUC-Loc-052222	Lepisosteus oculatus	74.46	0.00e+00	759.00
IUUC-Laf-054499	Loxodonta africana	64.44	0.00e+00	716.00
IUUC-Meu-056879	Macropus eugenii	67.12	0.00e+00	718.00
IUUC-Mga-059971	Meleagris gallopavo	70.20	0.00e+00	751.00
IUUC-Mmr-060740	Microcebus murinus	68.63	0.00e+00	735.00
IUUC-Mdo-062192	Monodelphis domestica	69.02	0.00e+00	740.00
IUUC-Mmu-064241	Mus musculus	68.63	0.00e+00	736.00
IUUC-Mpu-066595	Mustela putorius furo	68.24	0.00e+00	731.00
IUUC-Mlu-067069	Myotis lucifugus	68.10	0.00e+00	732.00
IUUC-Opr-070472	Ochotona princeps	65.23	0.00e+00	718.00
IUUC-Ocu-074221	Oryctolagus cuniculus	67.71	0.00e+00	722.00
IUUC-Ola-087000	Oryzias latipes	85.12	0.00e+00	897.00
IUUC-Oga-088225	Otolemur garnettii	67.84	0.00e+00	726.00
IUUC-Oar-090244	Ovis aries	60.00	0.00e+00	680.00
IUUC-Pan-091804	Papio anubis	68.63	0.00e+00	736.00
IUUC-Psi-093252	Pelodiscus sinensis	63.69	0.00e+00	654.00
IUUC-Pfo-096542	Poecilia formosa	88.54	0.00e+00	949.00
IUUC-Pab-098168	Pongo abelii	70.40	0.00e+00	709.00
IUUC-Rno-105542	Rattus norvegicus	68.43	0.00e+00	736.00
IUUC-Sha-107524	Sarcophilus harrisii	68.43	0.00e+00	736.00
IUUC-Sar-113235	Sorex araneus	63.79	1.00e-177	615.00
IUUC-Ssc-115624	Sus scrofa	68.24	0.00e+00	730.00
IUUC-Tru-118559	Takifugu rubripes	82.39	0.00e+00	877.00
IUUC-Tni-119928	Tetraodon nigroviridis	75.78	0.00e+00	793.00
IUUC-Ttr-129002	Tursiops truncatus	62.04	0.00e+00	675.00
IUUC-Xtr-132224	Xenopus tropicalis	69.80	0.00e+00	737.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence