iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115699

UUCD1 version

UUC-SuS-00807

Ensembl Protein ID

ENSSSCP00000026157.1

UniProt Accession

I3LPY0; I3LPY0_PIG

Protein Name

Uncharacterized protein

Gene Name

CDC34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000023616.1	ENSSSCT00000028657.1	ENSSSCP00000026157.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.70e-34	117.7	2	109

Active Site

Position(s)	Description	Evidence
49	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 35   lGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk...........eeekWspalsvesvllsiqsllaep 112
           +Gp+    egg+Fk++++fp dYP++PP ++fltk++hPn+ye+G+vC+sil+           ++e+W+p+++v+++lls++sll+ep
   Q: 2    EGPSWLAXEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHppvddpqsgelPSERWNPTQNVRTILLSVISLLNEP 90
           577777789*******************************************999999999*9************************** PP
   S: 113  npesplneeaaellkknre 131
           n+ sp+n++a+ +++k++e
   Q: 91   NTFSPANVDASVMYRKWKE 109
           ****************998 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

VEGPSWLAXE GGYFKARLKF PIDYPYSPPA FRFLTKMWHP NIYETGDVCI SILHPPVDDP 60
QSGELPSERW NPTQNVRTIL LSVISLLNEP NTFSPANVDA SVMYRKWKES KGRDREFTAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGAGGGAC CCTCTTGGCT GGCCCNCGAG GGCGGCTACT TCAAGGTGAG CAGCGAAGAG 60
GGGGGCGGGC GAGCGACCCT GCTCCGGGTC CTCGGGGCCC CTCCTCCACC TCTGCTCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0035458--P:cellular response to interferon-beta
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001600	Ailuropoda melanoleuca	91.11	4.00e-94	337.00
IUUC-Apl-003563	Anas platyrhynchos	81.63	3.00e-72	263.00
IUUC-Aca-004589	Anolis carolinensis	79.62	2.00e-74	271.00
IUUC-Acl-008052	Aspergillus clavatus	52.67	2.00e-28	118.00
IUUC-Ani-009262	Aspergillus nidulans	51.15	2.00e-28	119.00
IUUC-Ang-009716	Aspergillus niger	47.37	8.00e-27	113.00
IUUC-Ate-010563	Aspergillus terreus	44.83	1.00e-29	122.00
IUUC-Ame-011425	Astyanax mexicanus	84.57	2.00e-80	291.00
IUUC-Bta-012516	Bos taurus	92.70	1.00e-86	312.00
IUUC-Cel-018460	Caenorhabditis elegans	65.36	9.00e-57	213.00
IUUC-Cja-018764	Callithrix jacchus	80.25	7.00e-75	272.00
IUUC-Cfa-020203	Canis familiaris	91.36	3.00e-85	307.00
IUUC-Cpo-022139	Cavia porcellus	85.08	1.00e-87	315.00
IUUC-Csa-023371	Chlorocebus sabaeus	86.11	6.00e-86	309.00
IUUC-Cin-025257	Ciona intestinalis	70.13	2.00e-63	234.00
IUUC-Csv-025954	Ciona savignyi	68.79	5.00e-64	236.00
IUUC-Dre-028367	Danio rerio	83.95	2.00e-80	291.00
IUUC-Dno-029368	Dasypus novemcinctus	80.25	2.00e-74	271.00
IUUC-Dor-030875	Dipodomys ordii	86.19	1.00e-86	311.00
IUUC-Dme-032106	Drosophila melanogaster	67.70	2.00e-64	238.00
IUUC-Ete-033001	Echinops telfairi	80.70	1.00e-52	198.00
IUUC-Eca-034221	Equus caballus	81.51	3.00e-71	260.00
IUUC-Fca-035832	Felis catus	93.98	4.00e-90	322.00
IUUC-Fal-036936	Ficedula albicollis	92.47	4.00e-79	286.00
IUUC-Gmo-039414	Gadus morhua	84.57	4.00e-81	293.00
IUUC-Gga-040694	Gallus gallus	84.62	5.00e-85	306.00
IUUC-Gac-042485	Gasterosteus aculeatus	84.38	5.00e-81	293.00
IUUC-Ggo-044806	Gorilla gorilla	86.11	5.00e-86	310.00
IUUC-Hsa-046245	Homo sapiens	86.11	6.00e-86	309.00
IUUC-Itr-047928	Ictidomys tridecemlineatus	93.24	1.00e-80	291.00
IUUC-Lch-049845	Latimeria chalumnae	86.88	1.00e-81	295.00
IUUC-Loc-052932	Lepisosteus oculatus	86.25	4.00e-82	296.00
IUUC-Laf-053860	Loxodonta africana	80.25	7.00e-75	272.00
IUUC-Mcc-054665	Macaca mulatta	86.11	8.00e-86	309.00
IUUC-Meu-056360	Macropus eugenii	94.56	7.00e-81	292.00
IUUC-Mga-060075	Meleagris gallopavo	84.62	5.00e-85	306.00
IUUC-Mmr-061165	Microcebus murinus	87.15	5.00e-86	310.00
IUUC-Mdo-061825	Monodelphis domestica	90.74	8.00e-85	305.00
IUUC-Mmu-064168	Mus musculus	91.36	3.00e-85	307.00
IUUC-Mpu-066009	Mustela putorius furo	91.11	7.00e-94	336.00
IUUC-Mlu-067860	Myotis lucifugus	94.51	3.00e-82	296.00
IUUC-Nle-070152	Nomascus leucogenys	89.42	3.00e-55	205.00
IUUC-Opr-070826	Ochotona princeps	84.57	7.00e-86	309.00
IUUC-Ont-071745	Oreochromis niloticus	85.62	1.00e-81	295.00
IUUC-Oan-073287	Ornithorhynchus anatinus	82.35	4.00e-81	293.00
IUUC-Ocu-074902	Oryctolagus cuniculus	92.16	2.00e-82	298.00
IUUC-Ola-086976	Oryzias latipes	84.71	1.00e-79	288.00
IUUC-Oga-088845	Otolemur garnettii	88.83	1.00e-90	325.00
IUUC-Oar-090180	Ovis aries	95.73	9.00e-83	298.00
IUUC-Ptr-090916	Pan troglodytes	91.36	2.00e-85	308.00
IUUC-Pan-092577	Papio anubis	86.11	6.00e-86	309.00
IUUC-Psi-093039	Pelodiscus sinensis	85.29	5.00e-81	292.00
IUUC-Pma-094368	Petromyzon marinus	79.33	5.00e-71	259.00
IUUC-Pfo-096435	Poecilia formosa	85.00	2.00e-81	294.00
IUUC-Pab-098200	Pongo abelii	86.11	1.00e-85	308.00
IUUC-Pca-100169	Procavia capensis	85.71	1.00e-65	241.00
IUUC-Pva-102875	Pteropus vampyrus	95.24	3.00e-81	293.00
IUUC-Rno-106079	Rattus norvegicus	91.36	3.00e-85	307.00
IUUC-Sha-106475	Sarcophilus harrisii	91.61	1.00e-81	294.00
IUUC-Sar-112992	Sorex araneus	82.00	8.00e-74	269.00
IUUC-Tgu-117466	Taeniopygia guttata	84.07	8.00e-85	306.00
IUUC-Tru-117589	Takifugu rubripes	80.49	5.00e-76	276.00
IUUC-Tsy-118797	Tarsius syrichta	81.88	4.00e-67	246.00
IUUC-Tni-120864	Tetraodon nigroviridis	80.86	2.00e-77	281.00
IUUC-Tbe-128014	Tupaia belangeri	80.25	7.00e-75	272.00
IUUC-Ttr-128729	Tursiops truncatus	88.76	4.00e-82	296.00
IUUC-Vpa-130680	Vicugna pacos	81.94	2.00e-70	257.00
IUUC-Xtr-132285	Xenopus tropicalis	88.12	3.00e-82	297.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence