iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sja-107786

Ensembl Protein ID

EEB09397

UniProt Accession

B6K793; B6K793_SCHJY

Genbank Protein ID

EEB09397.1

Protein Name

HECT-type ubiquitin-protein ligase E3 Pub1

Genbank Nucleotide ID

KE651168

Gene Name

SJAG_04600

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SJAG_04600	EEB09397	EEB09397

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.40e-126	420.4	431	760

Active Site

Position(s)	Description	Evidence
729	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllgkk 104
           +lkkrl+++f+gE+gld+gG++ref++lls+++++p ++lf+ys+ d++tlq+np+s + npehl++F+f+Gr++g+a++++r+ld+++  s+yk+ll+kk
   Q: 431  ELKKRLMIRFEGEDGLDYGGLSREFFFLLSHKMFDPIYCLFEYSAVDNYTLQINPHSSI-NPEHLNYFKFIGRVIGLAIFHRRFLDAFFVVSLYKMLLRKK 530
           799*******************************************************9.89*************************************** PP
   S: 105  lsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplel 205
           ++l d+e++d+e+y+slk+i++n   di+ + ldltf ++e+++ge++++eLkp+G++i+Vt++Nk+eYv+lv+++r++++++eq++af++Gf ++ip+el
   Q: 531  VTLADMESIDAEFYRSLKWILDN---DITGI-LDLTFIAEEDHFGEVRTVELKPNGDQIEVTEDNKKEYVELVTQWRVTKRVEEQFNAFYDGFIDIIPPEL 627
           *********************99...9***9.********************************************************************* PP
   S: 206  lslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfvirkdasddrlPssn 302
           +++F+e+elelli G +++dved+k +t+y+  yt++++++ wFw++++++++e+r+++LqF+Tg+sr+P++Gf++l+    pr+f+i+k++s ++lP ++
   Q: 628  INIFDERELELLIGGISDVDVEDWKTNTEYRT-YTSTDQVVVWFWDIISSWENEKRSRLLQFATGTSRIPVNGFRDLQgsdgPRKFTIEKAGSAEQLPVAH 727
           ******************************99.******************************************************************** PP
   S: 303  TCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           TCfn+L+LP+Y+ske l ++L++Aie+t gF+ 
   Q: 728  TCFNRLDLPPYESKERLDDRLTMAIENTIGFGN 760
           ******************************985 PP

Organism

Schizosaccharomyces japonicus

Protein Sequence
(Fasta)

MEQNTCKIRF SIVSADGLSK RDLFRTPDPF AVLTIDGEQT RTTKVVKKSL NPYWNESFDI 60
NVRPSSSILV RIFDQKRYKK KDQGFLGLVT FRVQEVVNLS SSRETLVTRQ LRKSSNSSSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGATGCTGCC ATAGCTTCCG TAGTCCCTGC TAGCTGTCTT CCTCCCTCCA CCCAACACAC 60
CGACTGCTCC GTTTCGCTTA AAGCGTTTCC TGTCGCCAAT TGCTGTTCCT CCGCGAGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001201	Ailuropoda melanoleuca	50.54	6.00e-165	573.00
IUUC-Apl-003886	Anas platyrhynchos	47.97	4.00e-154	536.00
IUUC-Aca-005388	Anolis carolinensis	48.84	2.00e-152	531.00
IUUC-Ame-010601	Astyanax mexicanus	48.76	5.00e-160	556.00
IUUC-Bta-012453	Bos taurus	48.48	1.00e-153	535.00
IUUC-Cel-018299	Caenorhabditis elegans	47.32	9.00e-153	531.00
IUUC-Cja-019034	Callithrix jacchus	50.27	7.00e-163	566.00
IUUC-Cfa-020258	Canis familiaris	50.63	1.00e-163	569.00
IUUC-Cpo-021648	Cavia porcellus	50.36	5.00e-160	556.00
IUUC-Csa-023334	Chlorocebus sabaeus	50.99	2.00e-162	564.00
IUUC-Cin-025212	Ciona intestinalis	47.54	2.00e-151	527.00
IUUC-Csv-026256	Ciona savignyi	46.90	1.00e-150	524.00
IUUC-Dre-028809	Danio rerio	48.94	3.00e-159	553.00
IUUC-Dno-029466	Dasypus novemcinctus	48.24	4.00e-156	543.00
IUUC-Dor-030176	Dipodomys ordii	49.64	1.00e-155	541.00
IUUC-Dme-032041	Drosophila melanogaster	48.01	2.00e-149	520.00
IUUC-Ete-032779	Echinops telfairi	47.51	2.00e-140	491.00
IUUC-Eca-033441	Equus caballus	49.28	9.00e-157	545.00
IUUC-Eeu-035247	Erinaceus europaeus	46.62	2.00e-154	538.00
IUUC-Fca-036384	Felis catus	50.54	3.00e-163	567.00
IUUC-Fal-037547	Ficedula albicollis	48.75	1.00e-154	538.00
IUUC-Gmo-039679	Gadus morhua	48.95	6.00e-155	539.00
IUUC-Gga-040524	Gallus gallus	49.29	7.00e-156	542.00
IUUC-Gac-042607	Gasterosteus aculeatus	48.69	7.00e-153	532.00
IUUC-Ggo-045332	Gorilla gorilla	48.07	1.00e-155	541.00
IUUC-Hsa-046479	Homo sapiens	50.63	6.00e-164	570.00
IUUC-Itr-048860	Ictidomys tridecemlineatus	48.75	2.00e-151	528.00
IUUC-Lch-050443	Latimeria chalumnae	48.07	1.00e-155	541.00
IUUC-Loc-052645	Lepisosteus oculatus	51.61	6.00e-156	542.00
IUUC-Laf-053850	Loxodonta africana	48.24	9.00e-156	542.00
IUUC-Mcc-055585	Macaca mulatta	50.99	1.00e-162	565.00
IUUC-Meu-056436	Macropus eugenii	46.59	1.00e-119	422.00
IUUC-Mga-059986	Meleagris gallopavo	48.66	2.00e-152	531.00
IUUC-Mmr-061061	Microcebus murinus	50.18	5.00e-165	573.00
IUUC-Mmu-064136	Mus musculus	48.24	3.00e-156	543.00
IUUC-Mpu-066567	Mustela putorius furo	50.27	2.00e-162	564.00
IUUC-Mlu-068148	Myotis lucifugus	50.36	2.00e-163	568.00
IUUC-Nle-069225	Nomascus leucogenys	50.72	8.00e-164	569.00
IUUC-Opr-071044	Ochotona princeps	46.88	2.00e-154	537.00
IUUC-Ont-071822	Oreochromis niloticus	48.51	3.00e-159	553.00
IUUC-Oan-073019	Ornithorhynchus anatinus	48.32	2.00e-152	531.00
IUUC-Ocu-074409	Oryctolagus cuniculus	51.17	3.00e-163	567.00
IUUC-Ola-086526	Oryzias latipes	48.23	1.00e-159	554.00
IUUC-Oga-088460	Otolemur garnettii	48.24	1.00e-155	541.00
IUUC-Oar-089797	Ovis aries	49.10	7.00e-156	542.00
IUUC-Ptr-091629	Pan troglodytes	50.63	3.00e-164	570.00
IUUC-Pan-092284	Papio anubis	48.07	6.00e-156	543.00
IUUC-Psi-093618	Pelodiscus sinensis	48.56	1.00e-154	538.00
IUUC-Pma-094364	Petromyzon marinus	52.55	4.00e-143	499.00
IUUC-Pfo-097145	Poecilia formosa	47.63	4.00e-151	526.00
IUUC-Pab-098394	Pongo abelii	50.81	6.00e-163	566.00
IUUC-Pca-100568	Procavia capensis	48.22	5.00e-144	503.00
IUUC-Pva-102354	Pteropus vampyrus	48.24	8.00e-156	542.00
IUUC-Rno-105318	Rattus norvegicus	48.24	3.00e-156	543.00
IUUC-Sha-107482	Sarcophilus harrisii	48.00	8.00e-153	532.00
IUUC-Stu-112894	Solanum tuberosum	35.26	9.00e-55	206.00
IUUC-Ssc-115368	Sus scrofa	48.76	5.00e-150	523.00
IUUC-Tgu-117474	Taeniopygia guttata	49.55	2.00e-155	541.00
IUUC-Tsy-119492	Tarsius syrichta	48.24	7.00e-154	536.00
IUUC-Tbe-127793	Tupaia belangeri	48.77	6.00e-134	469.00
IUUC-Ttr-128235	Tursiops truncatus	53.20	4.00e-146	510.00
IUUC-Uma-129332	Ustilago maydis	67.74	0.00e+00	806.00
IUUC-Vpa-130503	Vicugna pacos	48.20	1.00e-150	525.00
IUUC-Xtr-132859	Xenopus tropicalis	48.74	2.00e-156	545.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence