iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-087384

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BAAF04033483

Gene Name

hectd3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000003223.1	ENSORLT00000004017.1	ENSORLP00000004016.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.10e-74	252.1	530	857

Active Site

Position(s)	Description	Evidence
827	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 8    rlevefvgEegldlgGvtreflallskelqnpd......lglflysendketlqpnp.dsglknp..ehlklFeflGrllgkalqdgrl 87
            +e++f  E  +d+gG +r+ la +s+el+ ++      l++fl+++n+ ++ + +  d ++ np  + ++ +e++G+l+g al+ + +
   Q: 530  WWECKFIAEGIIDQGGGFRDSLADMSEELCPSSaecpipLPFFLRTSNQCCQGSLEArDYYVPNPscKDFQKYEWIGQLMGAALRGKDF 618
           356******************************9999999***9999987777766505555555999********************* PP
   S: 88   ldlplsksfyklllgkklsl.edleevdpelykslkeikenaesdieelgldltfs...vseeilgetkeeeLkpgGenipVtneNkee 172
           l l l+  ++k+l g+ +s+ +d+++vd+ l++ l+ +++     +++++++++f    v +++l + + +eL+pgG+++ V +e+++e
   Q: 619  LVLALPGLVWKQLTGEAISWsKDFPSVDSVLVNLLEAMEN-----MDKETFEFRFGeelVYNTLLTDGQMVELIPGGSSVAVRYEDRSE 702
           ***************************************5.....5666778888755677788************************* PP
   S: 173  YvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseer 261
           +v+lv ++rl+e  k+q++a+++G+ +v+p+ +l+l+t++e+e  +cG++ei+ve+lk+ t++++ +++++  +q++we+l++f++e+r
   Q: 703  FVHLVQKARLEE-SKQQIAAMQAGLLKVVPQAVLDLLTWQEVEKKVCGDPEISVEALKRLTRFED-LEHNDVRVQYLWEALRNFTNEDR 789
           ***********9.9*************************************************76.*********************** PP
   S: 262  kafLqFvTgssrlPlgGfaelkprlfvirk..dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           ++fL+FvTg+srlP+       p  +  +k  ++++d lP+s+TC ++L LP+Y+s ++++ekL+yA  ++ +++
   Q: 790  SRFLRFVTGRSRLPA-------PIYVFPEKqgSETTDALPQSSTCSSTLYLPNYPSAKVCEEKLRYAAYNCVAID 857
           **************5.......44466677788888*********************************998776 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

VSYPTPRSLG DSPHLLLGRI RFLNSCIESF RKSEPVPESL CYVPREVCYK ICKDSSSNFS 60
ASSGATSGGS LVGKTLVSVF ESPHQTPHNK KSCKFSIEPK KGTCIRTTGE EYCNSQGLWV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCAGTTACC CAACACCTAG CTAGGTTGCT AATATGAGCA CACACACACG TATTTCATTG 60
TTTTCAATGA AAAAGGTTTA TCTGGTGATG AAAACGTGTC TGCTTGGATG TAGATGGTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR004939--APC_su10/DOC_dom
IPR008979--Galactose-bd-like
IPR000569--HECT_dom

PROSITE

PS51284--DOC
PS50237--HECT

Pfam

PF03256--ANAPC10
PF00632--HECT

SMART

SM01337--APC10
SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001229	Ailuropoda melanoleuca	69.14	0.00e+00	1228.00
IUUC-Apl-003715	Anas platyrhynchos	78.44	0.00e+00	1209.00
IUUC-Aca-004377	Anolis carolinensis	72.85	0.00e+00	1286.00
IUUC-Ame-011918	Astyanax mexicanus	78.32	0.00e+00	1360.00
IUUC-Bta-012736	Bos taurus	69.72	0.00e+00	1241.00
IUUC-Cja-019926	Callithrix jacchus	69.76	0.00e+00	1238.00
IUUC-Cfa-020753	Canis familiaris	78.37	0.00e+00	970.00
IUUC-Cpo-021415	Cavia porcellus	69.61	0.00e+00	1236.00
IUUC-Csa-023096	Chlorocebus sabaeus	69.61	0.00e+00	1237.00
IUUC-Dre-028746	Danio rerio	85.26	0.00e+00	1441.00
IUUC-Dno-029293	Dasypus novemcinctus	78.57	0.00e+00	890.00
IUUC-Dor-031113	Dipodomys ordii	77.89	0.00e+00	1016.00
IUUC-Ete-032601	Echinops telfairi	68.00	0.00e+00	1078.00
IUUC-Eca-034198	Equus caballus	67.97	0.00e+00	1221.00
IUUC-Eeu-034708	Erinaceus europaeus	79.06	0.00e+00	754.00
IUUC-Fca-035478	Felis catus	70.40	0.00e+00	1228.00
IUUC-Fal-037366	Ficedula albicollis	71.40	0.00e+00	1252.00
IUUC-Gmo-039020	Gadus morhua	87.82	0.00e+00	1198.00
IUUC-Gga-040332	Gallus gallus	73.69	0.00e+00	1301.00
IUUC-Gac-042336	Gasterosteus aculeatus	88.84	0.00e+00	1566.00
IUUC-Ggo-045382	Gorilla gorilla	69.61	0.00e+00	1237.00
IUUC-Hsa-046562	Homo sapiens	69.61	0.00e+00	1237.00
IUUC-Itr-048208	Ictidomys tridecemlineatus	69.49	0.00e+00	1234.00
IUUC-Lch-049606	Latimeria chalumnae	64.29	0.00e+00	806.00
IUUC-Loc-052448	Lepisosteus oculatus	72.19	0.00e+00	1230.00
IUUC-Laf-054507	Loxodonta africana	69.18	0.00e+00	1248.00
IUUC-Mcc-055690	Macaca mulatta	69.49	0.00e+00	1235.00
IUUC-Meu-055970	Macropus eugenii	68.87	0.00e+00	1199.00
IUUC-Mga-059654	Meleagris gallopavo	78.66	0.00e+00	1193.00
IUUC-Mmr-061069	Microcebus murinus	69.49	0.00e+00	1234.00
IUUC-Mdo-062547	Monodelphis domestica	79.48	0.00e+00	697.00
IUUC-Mmu-063096	Mus musculus	68.57	0.00e+00	1233.00
IUUC-Mpu-065846	Mustela putorius furo	69.49	0.00e+00	1241.00
IUUC-Mlu-067992	Myotis lucifugus	73.51	0.00e+00	1200.00
IUUC-Nle-069565	Nomascus leucogenys	68.31	0.00e+00	1140.00
IUUC-Opr-070853	Ochotona princeps	65.45	0.00e+00	810.00
IUUC-Ont-071628	Oreochromis niloticus	89.28	0.00e+00	1541.00
IUUC-Ocu-074094	Oryctolagus cuniculus	69.37	0.00e+00	1236.00
IUUC-Oga-088224	Otolemur garnettii	69.30	0.00e+00	1238.00
IUUC-Oar-090043	Ovis aries	67.63	0.00e+00	1179.00
IUUC-Ptr-090852	Pan troglodytes	69.37	0.00e+00	1228.00
IUUC-Pan-092787	Papio anubis	69.49	0.00e+00	1234.00
IUUC-Psi-092986	Pelodiscus sinensis	66.76	0.00e+00	892.00
IUUC-Pma-094416	Petromyzon marinus	39.58	5.00e-175	608.00
IUUC-Pfo-096720	Poecilia formosa	90.33	0.00e+00	1596.00
IUUC-Pab-098325	Pongo abelii	65.84	0.00e+00	914.00
IUUC-Pca-100885	Procavia capensis	63.27	0.00e+00	931.00
IUUC-Pva-102829	Pteropus vampyrus	57.74	0.00e+00	723.00
IUUC-Rno-104882	Rattus norvegicus	69.61	0.00e+00	1236.00
IUUC-Sha-106811	Sarcophilus harrisii	77.36	2.00e-99	355.00
IUUC-Sar-113020	Sorex araneus	69.36	6.00e-173	601.00
IUUC-Ssc-115436	Sus scrofa	69.12	3.00e-112	397.00
IUUC-Tgu-117042	Taeniopygia guttata	74.04	0.00e+00	1303.00
IUUC-Tru-118419	Takifugu rubripes	85.26	0.00e+00	1451.00
IUUC-Tsy-118829	Tarsius syrichta	70.02	0.00e+00	736.00
IUUC-Tni-120410	Tetraodon nigroviridis	72.83	0.00e+00	1179.00
IUUC-Tbe-128113	Tupaia belangeri	78.85	0.00e+00	645.00
IUUC-Ttr-128167	Tursiops truncatus	65.94	0.00e+00	1148.00
IUUC-Xtr-132910	Xenopus tropicalis	63.16	0.00e+00	1055.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence