iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012594

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02045749

Gene Name

KLHL22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000020161.4	ENSBTAT00000026853.4	ENSBTAP00000026853.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.40e-18	65.9	51	115
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	9.60e-07	28.1	150	179

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lvv+g++ +ah+i Laas+++F+ +f ++l+e++ +++v i++v++ ++ ++l+F+Yt++l++
   Q: 51   DVVLVVEGKQLEAHRILLAASCDYFRGMFAGGLKEME-QEEVLIHGVSYNAMCQILHFIYTSELEL 115
           9***********************************8.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
           +N l+++r+A+l+d+++L ++ + +ilk+F
   Q: 150  DNILDVYRLAELFDLSRLTEQLDAYILKNF 179
           8***************************** PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MAEEQEFARL CKLPTQPSHP HCVSSTYRSA QHSQALLRGL LALRDSGILF DVVLVVEGKQ 60
LEAHRILLAA SCDYFRGMFA GGLKEMEQEE VLIHGVSYNA MCQILHFIYT SELELSLSNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGGTTGACT TTCTAATTAT TAACTTTTAA AAGTTCTTAT TTAAAAAAAA AAGTCCCTGG 60
AGTGCTTAAA GGTCCACCTG CCGACGTAGG AGACACCAGT TCGGATCCGG GAAGATCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0000070--P:mitotic sister chromatid segregation
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination

KEGG

bta:540134

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	94.01	0.00e+00	1188.00
IUUC-Apl-004081	Anas platyrhynchos	76.49	0.00e+00	1006.00
IUUC-Aca-005015	Anolis carolinensis	66.61	0.00e+00	848.00
IUUC-Ame-011712	Astyanax mexicanus	58.71	0.00e+00	708.00
IUUC-Cja-019752	Callithrix jacchus	93.47	0.00e+00	993.00
IUUC-Cfa-020884	Canis familiaris	94.48	0.00e+00	1229.00
IUUC-Cpo-021711	Cavia porcellus	92.74	0.00e+00	1213.00
IUUC-Csa-023211	Chlorocebus sabaeus	94.01	0.00e+00	1224.00
IUUC-Dre-028395	Danio rerio	59.93	0.00e+00	746.00
IUUC-Dno-030096	Dasypus novemcinctus	90.91	0.00e+00	1186.00
IUUC-Dor-030709	Dipodomys ordii	91.89	0.00e+00	680.00
IUUC-Eca-033388	Equus caballus	94.79	0.00e+00	1233.00
IUUC-Eeu-034616	Erinaceus europaeus	81.86	0.00e+00	1053.00
IUUC-Fca-035815	Felis catus	94.16	0.00e+00	1228.00
IUUC-Fal-037311	Ficedula albicollis	79.35	0.00e+00	994.00
IUUC-Gmo-039571	Gadus morhua	52.08	1.00e-156	546.00
IUUC-Gga-040992	Gallus gallus	76.33	0.00e+00	1006.00
IUUC-Gac-042041	Gasterosteus aculeatus	56.12	0.00e+00	681.00
IUUC-Ggo-045141	Gorilla gorilla	88.33	0.00e+00	1147.00
IUUC-Hsa-045984	Homo sapiens	94.16	0.00e+00	1226.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	94.32	0.00e+00	1229.00
IUUC-Lch-049700	Latimeria chalumnae	59.75	0.00e+00	716.00
IUUC-Loc-052141	Lepisosteus oculatus	61.67	0.00e+00	815.00
IUUC-Laf-053487	Loxodonta africana	92.70	0.00e+00	1193.00
IUUC-Mcc-054682	Macaca mulatta	93.58	0.00e+00	983.00
IUUC-Meu-055937	Macropus eugenii	72.57	0.00e+00	937.00
IUUC-Mga-059953	Meleagris gallopavo	76.33	0.00e+00	1006.00
IUUC-Mmr-061743	Microcebus murinus	93.38	0.00e+00	1211.00
IUUC-Mdo-062328	Monodelphis domestica	80.88	0.00e+00	1056.00
IUUC-Mmu-063979	Mus musculus	91.71	0.00e+00	1180.00
IUUC-Mpu-066750	Mustela putorius furo	94.01	0.00e+00	1226.00
IUUC-Mlu-066960	Myotis lucifugus	92.11	0.00e+00	1196.00
IUUC-Nle-069690	Nomascus leucogenys	94.79	0.00e+00	1105.00
IUUC-Opr-071059	Ochotona princeps	87.40	0.00e+00	1117.00
IUUC-Ont-072004	Oreochromis niloticus	57.29	0.00e+00	683.00
IUUC-Oan-073172	Ornithorhynchus anatinus	63.58	0.00e+00	736.00
IUUC-Ocu-074310	Oryctolagus cuniculus	93.94	2.00e-150	524.00
IUUC-Ola-086599	Oryzias latipes	56.85	0.00e+00	696.00
IUUC-Oga-087980	Otolemur garnettii	93.22	0.00e+00	1211.00
IUUC-Oar-089956	Ovis aries	82.57	0.00e+00	955.00
IUUC-Ptr-090598	Pan troglodytes	94.81	0.00e+00	1110.00
IUUC-Pan-092387	Papio anubis	93.39	0.00e+00	983.00
IUUC-Psi-093484	Pelodiscus sinensis	77.59	0.00e+00	1035.00
IUUC-Pma-094224	Petromyzon marinus	49.92	2.00e-172	598.00
IUUC-Pfo-096149	Poecilia formosa	57.63	0.00e+00	711.00
IUUC-Pab-098097	Pongo abelii	94.01	0.00e+00	1226.00
IUUC-Pca-100118	Procavia capensis	92.43	0.00e+00	682.00
IUUC-Pva-103174	Pteropus vampyrus	94.68	1.00e-152	533.00
IUUC-Rno-105350	Rattus norvegicus	91.56	0.00e+00	1162.00
IUUC-Sha-106817	Sarcophilus harrisii	80.15	2.00e-128	452.00
IUUC-Sar-113490	Sorex araneus	93.59	0.00e+00	633.00
IUUC-Ssc-115827	Sus scrofa	95.74	0.00e+00	1243.00
IUUC-Tgu-116748	Taeniopygia guttata	80.99	0.00e+00	890.00
IUUC-Tru-118644	Takifugu rubripes	57.49	0.00e+00	689.00
IUUC-Tsy-118888	Tarsius syrichta	88.71	0.00e+00	1012.00
IUUC-Tni-120060	Tetraodon nigroviridis	53.93	1.00e-174	606.00
IUUC-Ttr-129183	Tursiops truncatus	97.13	0.00e+00	1134.00
IUUC-Xtr-132780	Xenopus tropicalis	68.22	0.00e+00	895.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence