iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013443

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02048816

Gene Name

RNF222

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000039299.2	ENSBTAT00000056963.2	ENSBTAP00000055502.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.90e-09	38.0	24	75

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf....kdgplvlpCgHvfhadClqkw.....pglknssskefrCPlCr 46
           C++C+e f        ++l+CgHvf++dCl k+     ++ +   ++++ CP+Cr
   Q: 24   CPVCYEKFrelqG-ASRTLSCGHVFCHDCLVKYllstrVDGQ--VQRTIVCPICR 75
           ********65533.3889************999888665555..889999****8 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

TARALPSCSA MSEGESKDSS GSECPVCYEK FRELQGASRT LSCGHVFCHD CLVKYLLSTR 60
VDGQVQRTIV CPICRYVTFL SRKSSRWPAK LDKSSQILAV PVGLPPSPLP DALGHANPLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGCGAGGG CCCTGCCCTC CTGCTCGGCC ATGTCTGAGG GCGAGAGCAA GGACAGCTCG 60
GGCAGCGAGT GCCCCGTGTG CTATGAGAAG TTCCGAGAGC TGCAGGGCGC CAGCCGGACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0033768--C:SUMO-targeted ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0033234--P:negative regulation of protein sumoylation
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001331	Ailuropoda melanoleuca	81.72	1.00e-42	164.00
IUUC-Apl-003509	Anas platyrhynchos	46.61	1.00e-34	139.00
IUUC-Aca-004916	Anolis carolinensis	43.75	1.00e-24	105.00
IUUC-Cja-019637	Callithrix jacchus	80.19	2.00e-61	228.00
IUUC-Cfa-020737	Canis familiaris	80.98	2.00e-63	234.00
IUUC-Cpo-022224	Cavia porcellus	82.21	1.00e-63	235.00
IUUC-Csa-024175	Chlorocebus sabaeus	76.54	3.00e-69	254.00
IUUC-Dre-028060	Danio rerio	33.65	5.00e-21	94.00
IUUC-Dno-030024	Dasypus novemcinctus	78.53	1.00e-63	236.00
IUUC-Dor-030936	Dipodomys ordii	85.29	3.00e-74	271.00
IUUC-Eca-033759	Equus caballus	85.79	5.00e-77	280.00
IUUC-Fal-037142	Ficedula albicollis	43.20	4.00e-29	120.00
IUUC-Gmo-039196	Gadus morhua	36.27	1.00e-20	92.80
IUUC-Gga-041189	Gallus gallus	46.67	2.00e-30	125.00
IUUC-Gac-041497	Gasterosteus aculeatus	40.76	3.00e-24	104.00
IUUC-Ggo-045020	Gorilla gorilla	79.52	4.00e-67	247.00
IUUC-Hsa-046317	Homo sapiens	78.31	3.00e-61	227.00
IUUC-Itr-048656	Ictidomys tridecemlineatus	84.12	4.00e-75	273.00
IUUC-Lch-049885	Latimeria chalumnae	49.46	2.00e-21	95.10
IUUC-Laf-053457	Loxodonta africana	75.13	5.00e-65	240.00
IUUC-Mcc-054653	Macaca mulatta	76.58	6.00e-61	226.00
IUUC-Mga-059753	Meleagris gallopavo	46.81	4.00e-33	134.00
IUUC-Mdo-062993	Monodelphis domestica	70.05	8.00e-66	243.00
IUUC-Mmu-063225	Mus musculus	82.94	2.00e-68	251.00
IUUC-Mpu-066299	Mustela putorius furo	83.15	1.00e-64	238.00
IUUC-Mlu-066988	Myotis lucifugus	80.23	7.00e-65	239.00
IUUC-Nle-069011	Nomascus leucogenys	77.85	1.00e-62	232.00
IUUC-Opr-070258	Ochotona princeps	81.01	1.00e-66	245.00
IUUC-Ont-071886	Oreochromis niloticus	40.34	4.00e-23	100.00
IUUC-Ocu-074282	Oryctolagus cuniculus	86.47	9.00e-71	259.00
IUUC-Oga-088403	Otolemur garnettii	75.13	2.00e-65	241.00
IUUC-Oar-089665	Ovis aries	91.67	6.00e-26	108.00
IUUC-Ptr-090580	Pan troglodytes	78.92	1.00e-62	232.00
IUUC-Pan-092447	Papio anubis	77.22	1.00e-61	229.00
IUUC-Psi-093673	Pelodiscus sinensis	45.13	3.00e-37	147.00
IUUC-Ppa-095340	Physcomitrella patens	29.25	2.00e-07	49.30
IUUC-Pfo-096933	Poecilia formosa	39.75	3.00e-21	95.10
IUUC-Pab-097867	Pongo abelii	78.48	3.00e-59	221.00
IUUC-Pva-102146	Pteropus vampyrus	85.88	2.00e-74	271.00
IUUC-Rno-105897	Rattus norvegicus	84.71	1.00e-69	255.00
IUUC-Sha-107282	Sarcophilus harrisii	66.17	9.00e-54	202.00
IUUC-Sar-113260	Sorex araneus	85.29	6.00e-78	283.00
IUUC-Ssc-115449	Sus scrofa	84.86	2.00e-55	208.00
IUUC-Tgu-117349	Taeniopygia guttata	43.62	6.00e-28	116.00
IUUC-Xtr-132180	Xenopus tropicalis	52.75	9.00e-24	103.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence