iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062993

UUCD1 version

UUC-MoD-00707

Ensembl Protein ID

ENSMODP00000009950.2

UniProt Accession

F7D5E0; F7D5E0_MONDO

Protein Name

Uncharacterized protein

Gene Name

RNF222

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000007992.2	ENSMODT00000010142.2	ENSMODP00000009950.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.90e-09	37.1	14	65

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf....kdgplvlpCgHvfhadClqkw.....pglknssskefrCPlCr 46
           C++C+e f        ++l+CgHvf++dCl k+     ++ +   +k++ CP+Cr
   Q: 14   CPVCYEKFrdleG-ASRTLSCGHVFCHDCLVKYllsckVDGQ--IQKSIVCPICR 65
           ********55532.3899************999899777777..999999****8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSEGESKDSV GSECPVCYEK FRDLEGASRT LSCGHVFCHD CLVKYLLSCK VDGQIQKSIV 60
CPICRYVTFL SKKSSRWPSL SSEKSSQTLT VPVGLDNLPS LDALGHTNPL TIPHPLWVPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGAAG GAGAGAGCAA GGACAGTGTG GGCAGTGAGT GTCCTGTGTG CTATGAGAAG 60
TTTCGGGACC TAGAGGGAGC CAGCCGGACA CTGAGTTGCG GCCATGTCTT CTGCCATGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0033768--C:SUMO-targeted ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0033234--P:negative regulation of protein sumoylation
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001331	Ailuropoda melanoleuca	67.24	3.00e-42	163.00
IUUC-Atr-002488	Amborella trichopoda	33.33	2.00e-06	45.80
IUUC-Apl-003509	Anas platyrhynchos	46.58	8.00e-38	150.00
IUUC-Aca-004916	Anolis carolinensis	39.38	6.00e-24	103.00
IUUC-Aly-006067	Arabidopsis lyrata	33.82	6.00e-07	47.80
IUUC-Ath-007395	Arabidopsis thaliana	33.82	5.00e-07	48.10
IUUC-Bta-013443	Bos taurus	68.67	7.00e-55	206.00
IUUC-Cja-019637	Callithrix jacchus	72.60	3.00e-64	237.00
IUUC-Cfa-020737	Canis familiaris	70.78	2.00e-56	211.00
IUUC-Cpo-022224	Cavia porcellus	74.12	1.00e-63	235.00
IUUC-Csa-024175	Chlorocebus sabaeus	73.96	4.00e-69	254.00
IUUC-Dre-028060	Danio rerio	32.41	6.00e-23	100.00
IUUC-Dno-030024	Dasypus novemcinctus	72.46	5.00e-59	220.00
IUUC-Dor-030936	Dipodomys ordii	72.29	1.00e-62	232.00
IUUC-Eca-033759	Equus caballus	77.25	7.00e-72	263.00
IUUC-Fal-037142	Ficedula albicollis	48.65	3.00e-32	131.00
IUUC-Gmo-039196	Gadus morhua	34.95	6.00e-22	97.10
IUUC-Gga-041189	Gallus gallus	51.83	1.00e-37	149.00
IUUC-Gac-041497	Gasterosteus aculeatus	39.41	3.00e-23	101.00
IUUC-Ggo-045020	Gorilla gorilla	74.10	6.00e-67	246.00
IUUC-Hsa-046317	Homo sapiens	71.69	1.00e-62	232.00
IUUC-Itr-048656	Ictidomys tridecemlineatus	75.30	2.00e-67	248.00
IUUC-Lch-049885	Latimeria chalumnae	40.00	4.00e-25	107.00
IUUC-Laf-053457	Loxodonta africana	68.64	8.00e-60	223.00
IUUC-Mcc-054653	Macaca mulatta	73.58	2.00e-63	234.00
IUUC-Mga-059753	Meleagris gallopavo	51.46	2.00e-38	152.00
IUUC-Mmu-063225	Mus musculus	75.32	2.00e-62	231.00
IUUC-Mac-065325	Musa acuminata	30.88	4.00e-06	45.10
IUUC-Mpu-066299	Mustela putorius furo	68.83	1.00e-53	202.00
IUUC-Mlu-066988	Myotis lucifugus	67.86	2.00e-53	201.00
IUUC-Nle-069011	Nomascus leucogenys	72.96	5.00e-63	233.00
IUUC-Opr-070258	Ochotona princeps	71.34	3.00e-60	224.00
IUUC-Ont-071886	Oreochromis niloticus	40.00	2.00e-25	108.00
IUUC-Ocu-074282	Oryctolagus cuniculus	73.38	6.00e-61	226.00
IUUC-Oga-088403	Otolemur garnettii	68.64	4.00e-61	227.00
IUUC-Oar-089665	Ovis aries	77.55	8.00e-19	84.70
IUUC-Ptr-090580	Pan troglodytes	72.29	5.00e-64	237.00
IUUC-Pan-092447	Papio anubis	73.58	6.00e-64	236.00
IUUC-Psi-093673	Pelodiscus sinensis	44.49	1.00e-39	156.00
IUUC-Pfo-096933	Poecilia formosa	41.03	1.00e-21	96.30
IUUC-Pab-097867	Pongo abelii	72.33	4.00e-61	227.00
IUUC-Pva-102146	Pteropus vampyrus	73.49	3.00e-62	231.00
IUUC-Rno-105897	Rattus norvegicus	75.97	3.00e-62	231.00
IUUC-Sha-107282	Sarcophilus harrisii	83.98	2.00e-78	284.00
IUUC-Sar-113260	Sorex araneus	77.11	2.00e-69	254.00
IUUC-Ssc-115449	Sus scrofa	70.78	2.00e-48	185.00
IUUC-Tgu-117349	Taeniopygia guttata	44.58	5.00e-32	130.00
IUUC-Vda-129777	Verticillium dahliae	33.58	6.00e-08	52.00
IUUC-Xtr-132180	Xenopus tropicalis	42.51	1.00e-25	109.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence