iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000015400.2	ENSPPYT00000017902.1	ENSPPYP00000017203.1
ENSPPYG00000015400.2	ENSPPYT00000033465.1	ENSPPYP00000024203.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	4.80e-06	26.8	95	140

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 101  glldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
            ++d+lp+e+l+ i++ l  +ell+++ vc+rw++las+++lw+t+
   Q: 95   VSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL 140
           57899**************************************997 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MHRKHLQEIP DLSSNVATSF TWGWDSSKTS ELLSGMGVSA LEKEEPDSEN IPQELLSNLG 60
HPESPPRKRL KSKGSDKDFV IVRRPKLNRE NFPGVSWDSL PDELLLGIFS CLCLPELLKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACAGGT AAACGGATGC AAAAAGGGGA AGAGCATGAA ATGGACCCTC TTAATAATTC 60
TTTTAGGCCG CGAATATCGC TACTGGCTAA TATTGTTAGT AATGCTGTTA AGTGAATGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0033148--P:positive regulation of intracellular estrogen receptor signaling pathway
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051726--P:regulation of cell cycle
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002197	Ailuropoda melanoleuca	93.22	0.00e+00	649.00
IUUC-Atr-002711	Amborella trichopoda	25.00	2.00e-09	58.50
IUUC-Apl-003453	Anas platyrhynchos	64.53	6.00e-85	306.00
IUUC-Aca-005185	Anolis carolinensis	62.85	1.00e-116	412.00
IUUC-Ame-010665	Astyanax mexicanus	48.43	2.00e-72	266.00
IUUC-Bta-013450	Bos taurus	89.83	0.00e+00	657.00
IUUC-Cel-018410	Caenorhabditis elegans	27.78	1.00e-17	84.30
IUUC-Cja-019834	Callithrix jacchus	97.18	0.00e+00	699.00
IUUC-Cfa-020401	Canis familiaris	92.66	0.00e+00	671.00
IUUC-Cpo-022183	Cavia porcellus	90.68	0.00e+00	659.00
IUUC-Csa-023418	Chlorocebus sabaeus	98.59	0.00e+00	709.00
IUUC-Cho-024412	Choloepus hoffmanni	80.18	0.00e+00	671.00
IUUC-Cin-025248	Ciona intestinalis	30.60	1.00e-30	127.00
IUUC-Csv-026189	Ciona savignyi	29.62	3.00e-27	115.00
IUUC-Cme-027297	Cyanidioschyzon merolae	37.14	2.00e-07	50.10
IUUC-Dre-028032	Danio rerio	49.19	2.00e-84	305.00
IUUC-Dno-029222	Dasypus novemcinctus	91.81	0.00e+00	662.00
IUUC-Dor-030505	Dipodomys ordii	76.82	0.00e+00	640.00
IUUC-Dme-031972	Drosophila melanogaster	34.16	3.00e-37	149.00
IUUC-Ete-032234	Echinops telfairi	83.33	1.00e-116	412.00
IUUC-Eca-033944	Equus caballus	92.66	0.00e+00	671.00
IUUC-Eeu-035008	Erinaceus europaeus	83.17	1.00e-143	501.00
IUUC-Fca-035412	Felis catus	91.24	0.00e+00	661.00
IUUC-Fal-037337	Ficedula albicollis	61.36	1.00e-106	379.00
IUUC-Gmo-038934	Gadus morhua	43.08	9.00e-40	157.00
IUUC-Gga-041152	Gallus gallus	64.12	2.00e-124	439.00
IUUC-Gac-041819	Gasterosteus aculeatus	47.10	9.00e-65	240.00
IUUC-Ggo-045479	Gorilla gorilla	91.87	0.00e+00	816.00
IUUC-Hsa-046512	Homo sapiens	99.44	0.00e+00	715.00
IUUC-Itr-048515	Ictidomys tridecemlineatus	91.99	0.00e+00	628.00
IUUC-Lch-050115	Latimeria chalumnae	55.77	2.00e-108	385.00
IUUC-Loc-052554	Lepisosteus oculatus	50.14	5.00e-84	304.00
IUUC-Laf-053563	Loxodonta africana	91.19	9.00e-178	615.00
IUUC-Mcc-055143	Macaca mulatta	98.58	0.00e+00	704.00
IUUC-Meu-056593	Macropus eugenii	54.63	2.00e-108	385.00
IUUC-Mga-060084	Meleagris gallopavo	59.77	2.00e-83	301.00
IUUC-Mmr-060660	Microcebus murinus	95.20	0.00e+00	689.00
IUUC-Mdo-062363	Monodelphis domestica	69.49	3.00e-131	461.00
IUUC-Mmu-063287	Mus musculus	86.16	0.00e+00	630.00
IUUC-Mpu-065791	Mustela putorius furo	92.09	0.00e+00	669.00
IUUC-Mlu-067714	Myotis lucifugus	89.01	0.00e+00	628.00
IUUC-Nle-069823	Nomascus leucogenys	100.00	0.00e+00	717.00
IUUC-Opr-071046	Ochotona princeps	73.05	2.00e-104	372.00
IUUC-Ont-071820	Oreochromis niloticus	47.23	6.00e-53	201.00
IUUC-Ocu-074868	Oryctolagus cuniculus	90.96	0.00e+00	657.00
IUUC-Ola-086608	Oryzias latipes	48.36	4.00e-58	218.00
IUUC-Oga-089044	Otolemur garnettii	93.79	0.00e+00	680.00
IUUC-Oar-089650	Ovis aries	90.11	0.00e+00	655.00
IUUC-Ptr-090743	Pan troglodytes	99.44	0.00e+00	714.00
IUUC-Pan-092501	Papio anubis	98.59	0.00e+00	709.00
IUUC-Psi-094032	Pelodiscus sinensis	66.10	1.00e-128	452.00
IUUC-Pfo-097279	Poecilia formosa	47.37	2.00e-49	189.00
IUUC-Pca-100100	Procavia capensis	90.73	2.00e-179	621.00
IUUC-Pva-103181	Pteropus vampyrus	83.79	0.00e+00	702.00
IUUC-Rno-105091	Rattus norvegicus	88.14	0.00e+00	641.00
IUUC-Sha-107226	Sarcophilus harrisii	70.90	5.00e-136	477.00
IUUC-Ssc-115665	Sus scrofa	93.79	0.00e+00	680.00
IUUC-Tgu-116982	Taeniopygia guttata	61.49	8.00e-105	373.00
IUUC-Tru-118276	Takifugu rubripes	49.35	3.00e-61	228.00
IUUC-Tsy-119074	Tarsius syrichta	85.81	0.00e+00	749.00
IUUC-Tni-120702	Tetraodon nigroviridis	50.65	2.00e-42	165.00
IUUC-Tbe-127990	Tupaia belangeri	92.62	2.00e-160	558.00
IUUC-Ttr-128661	Tursiops truncatus	71.55	1.00e-128	452.00
IUUC-Vvi-131526	Vitis vinifera	23.93	1.00e-08	55.50
IUUC-Xtr-132166	Xenopus tropicalis	56.78	2.00e-102	365.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence