iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120107

UUCD1 version

UUC-TeN-01133

Ensembl Protein ID

ENSTNIP00000017645.1

UniProt Accession

H3DAV3; H3DAV3_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000014616.1	ENSTNIT00000017866.1	ENSTNIP00000017645.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.50e-116	388.3	260	880
ULD/UDP/UBQ/UBQ_Other	2.20e-08	34.0	163	231

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn ++l+e++l+ +++ ++n+enp ++ ge+++++++l++++w s++++v+pr+++++++++a++fsgy+
   Q: 260  CGLSNLGNTCFMNSALQCLSNASPLTEYFLNdQYEAEINRENPLGMRGEIAEAYADLVKQMWLSRSSYVAPRTFKTQVGRFAPQFSGYQ 348
           7******************************99******************************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ k+kp+  +++++   ++de     a+ ++  +n+s+i+d+F+g +ks+++c+ec +vs++++pf++l
   Q: 349  QQDSQELLAFLLDGLHEDLNRVKKKPYLALRDAE--GRPDEivakeAWTNHRLRNDSIIVDIFHGLFKSTLVCPECSKVSVTFDPFCYL 435
           ***************************9998887..6666667777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p+k+++ +e                                                                            
   Q: 436  TLPLPMKKDRTMEvflvrsdpqsrptqyrvvvpklgavtdlcyalsklcgvapenmmvadvynhrfhkiyrrddglnqimekddifvwv 524
           ********99999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 525  fstrcrrmdgermnlpvyfrerhnkhvgsststvlfgqpllitvpkhnliadvlydkilerigryvkraqspnsdsrasasasfasssq 613
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 614  avqgctssgasggshsdgasccagssngsnhtgacsetnglydgehrwvfprprspklftfsvvnsygtanisslpcdahstvaidwdt 702
           ***************************************************************************************** PP
   S: 186  ...............................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeq 243
                                           l++c+e ft+ e+l +++ +yc++ckk+q+a+kk++l++lP++L++hLkRfs+++  
   Q: 703  eskklhydeqeaeayekhesmlqpqkkkatvALKECIELFTTMETLGEHDPWYCPTCKKHQQATKKFDLWSLPRILVVHLKRFSYNR-- 789
           ***********************************************************************************9966.. PP
   S: 244  ksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgsta 330
           + r k+++ v+fp++ L++s+f+++p+ +   +++Y+Liav +H+G++++GHY+ay+kn+ ++ W +fdDs+V++ +e+++++   + a
   Q: 790  CWRDKLDTVVDFPIRdLNMSEFVCNPKAS---PYIYDLIAVSNHYGGMGGGHYTAYCKNKADGrWHYFDDSSVSSASEDQIVT---KAA 872
           6778*********************9976...9**************************76556*******************...*** PP
   S: 331  YvlfYkrr 338
           YvlfY+rr
   Q: 873  YVLFYQRR 880
           ******96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 14   tlkvnpsdtVaeLKekiekklgip.peqqrLiyk.....GkiL.eddktLadyglkdgstihllekksg 75
           t+ ++++dt+ ++ ++++++++ip + + rL++k      + L ++d t++d gl++g+++++++k+++
   Q: 163  TRYFSKADTIDTIEKEMRTLFKIPaEKETRLWNKymsntYEQLnKPDSTVQDAGLFHGQVLVIEQKNED 231
           4448999*****************777*****999987744457*********************9986 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

SAGATDSDSE PVAGQMPTPS TESQKQTIGS LLKTSLRKGD EWYLIDSRWF KQWKKYVGFD 60
SWDMYNVGER NLYPGPIDNS GLFSGEDQDT QALKEHLIDE LDYVLVPTEA WNKLVSWYSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGGCTGGCG CGACAGACTC CGACTCGGAG CCGGTTGCTG GTCAAATGCC AACCCCTTCA 60
ACCGAAAGCC AAAAGCAGAC AATCGGGTCT CTTTTGAAAA CGTCTCTAAG AAAGGGGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0034122--P:negative regulation of toll-like receptor signaling pathway
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002991	Amborella trichopoda	35.59	5.00e-95	342.00
IUUC-Apl-004068	Anas platyrhynchos	57.57	0.00e+00	957.00
IUUC-Ath-007343	Arabidopsis thaliana	35.48	9.00e-139	487.00
IUUC-Ago-007911	Ashbya gossypii	43.09	1.00e-63	238.00
IUUC-Ang-009562	Aspergillus niger	37.23	5.00e-55	210.00
IUUC-Ate-010323	Aspergillus terreus	37.24	8.00e-57	216.00
IUUC-Ame-011064	Astyanax mexicanus	72.12	0.00e+00	972.00
IUUC-Bgr-012277	Blumeria graminis	37.33	9.00e-63	236.00
IUUC-Csa-023828	Chlorocebus sabaeus	49.15	0.00e+00	796.00
IUUC-Cho-024595	Choloepus hoffmanni	59.32	0.00e+00	740.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	36.84	8.00e-64	239.00
IUUC-Cme-027338	Cyanidioschyzon merolae	38.27	2.00e-66	247.00
IUUC-Fca-035373	Felis catus	68.16	0.00e+00	1194.00
IUUC-Gac-042631	Gasterosteus aculeatus	81.82	0.00e+00	1051.00
IUUC-Gma-042884	Glycine max	34.83	1.00e-129	457.00
IUUC-Hsa-046551	Homo sapiens	49.15	0.00e+00	796.00
IUUC-Hvu-047108	Hordeum vulgare	55.28	5.00e-79	288.00
IUUC-Kpa-049332	Komagataella pastoris	33.94	5.00e-72	266.00
IUUC-Mcc-054881	Macaca mulatta	49.15	0.00e+00	797.00
IUUC-Mvi-060324	Microbotryum violaceum	33.08	8.00e-83	302.00
IUUC-Mmr-061400	Microcebus murinus	50.06	0.00e+00	807.00
IUUC-Mmu-063960	Mus musculus	62.01	0.00e+00	1154.00
IUUC-Mlu-066961	Myotis lucifugus	48.47	0.00e+00	790.00
IUUC-Opr-070740	Ochotona princeps	65.24	0.00e+00	842.00
IUUC-Ont-072573	Oreochromis niloticus	79.88	0.00e+00	1507.00
IUUC-Ocu-074066	Oryctolagus cuniculus	49.94	0.00e+00	805.00
IUUC-Ola-086553	Oryzias latipes	78.92	0.00e+00	1062.00
IUUC-Oar-089732	Ovis aries	50.76	0.00e+00	793.00
IUUC-Pan-092292	Papio anubis	49.15	0.00e+00	797.00
IUUC-Pfo-097060	Poecilia formosa	80.46	0.00e+00	1054.00
IUUC-Pab-098522	Pongo abelii	67.91	0.00e+00	840.00
IUUC-Pop-099333	Populus trichocarpa	50.00	2.00e-81	296.00
IUUC-Pva-103244	Pteropus vampyrus	49.10	0.00e+00	787.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	35.40	3.00e-81	296.00
IUUC-Spo-108291	Schizosaccharomyces pombe	32.27	2.00e-76	280.00
IUUC-Sly-111726	Solanum lycopersicum	37.57	1.00e-91	330.00
IUUC-Ssc-116345	Sus scrofa	48.32	0.00e+00	809.00
IUUC-Xtr-132305	Xenopus tropicalis	62.47	0.00e+00	1121.00
IUUC-Xma-133176	Xiphophorus maculatus	80.99	0.00e+00	1051.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence