iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040961

UUCD1 version

UUC-GaG-00320

Ensembl Protein ID

ENSGALP00000051003.1

UniProt Accession

A0A1D5PE05; A0A1D5PE05_CHICK

Genbank Protein ID

ENSGALP00000051003

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000193

Gene Name

HECTD4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000032685.1	ENSGALT00000080305.1	ENSGALP00000051003.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.70e-81	273.9	4052	4412

Active Site

Position(s)	Description	Evidence
4386	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglf.......lysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           d ++ ++++f+gEe+++++G++r+fl++++kelq+++l+l+       ++++++k+ l+p+p ++     +++lF+f+G+llg+a++
   Q: 4052 DPTYAFNIRFTGEEVHGTSGSFRHFLWQVCKELQSSSLSLLllcpssaVNKNKGKYILTPSPITY----AEEQLFHFFGQLLGIAIR 4134
           5667788*********************************9999999888888***********9....689*************** PP
   S: 84   dgrlldlplsksfyklllgkklsl.edleevdpelyks.lkeikenaesdieelgldltfs..vseei...............lget 151
            + +l+l+l +sf+k+l+g++l+   dl+e d  +y++ +k+ + n+e+++e+l+++++++  +  ++                 + 
   Q: 4135 ADVPLPLDLLPSFWKTLVGEPLDPdVDLQEADILTYNYiKKFENINDETELEALCAEIASQhlA--TEspdcpnkpcckftylTMTG 4219
           ************************99************55555566688999999999998532..334699********9655555 PP
   S: 152  keeeLkpgGenipVtneNkeeYvklvveyrlke.gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykg 237
           +e+eL+p+G+++pV +eNk+ Y  ++ ++r++e +  e+++a+r+G+ ++ipl+ll+ +t+ e+el +cG ++i++e lk++t+y+ 
   Q: 4220 EEVELCPRGRHVPVGWENKDVYAAAIRSLRMRElQTPECMTAVRAGLGSIIPLQLLTTLTPLEMELRTCGLPYINLEFLKAHTMYQV 4306
           6667*****************************99**************************************************** PP
   S: 238  gytedspaiqwFwevleefsseerkafLqFvTgssrlPl......gGfaelk....prlfvirk...dasddrlPssnTCfnyLkLP 311
           g++e++++i++Fw++le+f++ee ++f++F+++++r+P+      gG ++ +    p+++  ++    + d+r+++++TC++++kLP
   Q: 4307 GLMETDQHIEFFWSALEMFTQEELCKFIKFACNQERIPFtcpckdGGPDTAHvppyPMKIAPPDgaaGSPDSRYIRVETCMFMIKLP 4393
           *********************************************9999999998888888888*955555**************** PP
   S: 312  eYsskeilkekLlyAieet 330
           +Yss +i+ ekL+yAi+++
   Q: 4394 QYSSLDIMLEKLRYAIHYR 4412
           ****************986 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MGSPAAASAA ATAASDSAQW LSVKEETIFL HDGLIRVTDL AELPSEIVGV AEPGDTELEI 60
LTFETKNPTE LAERLRSVCG NQSNAYARLL EYRLNALRGL WNAQRQLALE EQHDRESSGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTCCC CGGCGGCCGC TTCGGCGGCG GCGACGGCGG CCAGCGACTC GGCGCAGTGG 60
CTGTCGGTGA AGGAGGAGAC CATCTTCCTG CACGACGGGC TGATCCGGGT CACCGATCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002256	Ailuropoda melanoleuca	91.80	0.00e+00	6876.00
IUUC-Apl-004161	Anas platyrhynchos	98.60	0.00e+00	5468.00
IUUC-Aca-005341	Anolis carolinensis	90.50	0.00e+00	6749.00
IUUC-Ame-011574	Astyanax mexicanus	81.64	0.00e+00	5069.00
IUUC-Bta-012514	Bos taurus	90.18	0.00e+00	1786.00
IUUC-Cja-019148	Callithrix jacchus	91.63	0.00e+00	5019.00
IUUC-Cfa-020499	Canis familiaris	93.03	0.00e+00	7433.00
IUUC-Cpo-021894	Cavia porcellus	93.90	0.00e+00	2695.00
IUUC-Csa-023079	Chlorocebus sabaeus	93.03	0.00e+00	7567.00
IUUC-Cho-024415	Choloepus hoffmanni	88.93	0.00e+00	4893.00
IUUC-Dre-027452	Danio rerio	79.76	0.00e+00	5090.00
IUUC-Dno-029595	Dasypus novemcinctus	92.88	0.00e+00	7592.00
IUUC-Dor-030849	Dipodomys ordii	95.40	0.00e+00	1766.00
IUUC-Ete-032563	Echinops telfairi	85.16	0.00e+00	1532.00
IUUC-Eca-034202	Equus caballus	91.99	0.00e+00	6849.00
IUUC-Eeu-035175	Erinaceus europaeus	92.59	0.00e+00	1018.00
IUUC-Fca-036295	Felis catus	93.07	0.00e+00	6821.00
IUUC-Fal-037003	Ficedula albicollis	97.55	0.00e+00	6998.00
IUUC-Gmo-038579	Gadus morhua	84.98	0.00e+00	2869.00
IUUC-Gac-041899	Gasterosteus aculeatus	85.11	0.00e+00	2912.00
IUUC-Ggo-045099	Gorilla gorilla	92.75	0.00e+00	6068.00
IUUC-Hsa-046331	Homo sapiens	92.77	0.00e+00	7430.00
IUUC-Itr-048190	Ictidomys tridecemlineatus	89.76	0.00e+00	1985.00
IUUC-Lch-049923	Latimeria chalumnae	83.99	0.00e+00	2639.00
IUUC-Loc-052630	Lepisosteus oculatus	85.22	0.00e+00	4096.00
IUUC-Laf-053394	Loxodonta africana	92.69	0.00e+00	7266.00
IUUC-Mcc-055763	Macaca mulatta	92.62	0.00e+00	7588.00
IUUC-Meu-056039	Macropus eugenii	88.72	0.00e+00	5036.00
IUUC-Mga-059500	Meleagris gallopavo	97.67	0.00e+00	7386.00
IUUC-Mmr-060868	Microcebus murinus	89.79	0.00e+00	7395.00
IUUC-Mdo-062772	Monodelphis domestica	93.19	0.00e+00	7748.00
IUUC-Mmu-063606	Mus musculus	91.98	0.00e+00	7631.00
IUUC-Mpu-065860	Mustela putorius furo	90.18	0.00e+00	6760.00
IUUC-Mlu-067376	Myotis lucifugus	92.05	0.00e+00	5145.00
IUUC-Nle-069693	Nomascus leucogenys	90.71	0.00e+00	7203.00
IUUC-Opr-071065	Ochotona princeps	91.58	0.00e+00	1162.00
IUUC-Ont-072470	Oreochromis niloticus	83.01	0.00e+00	4659.00
IUUC-Oan-073693	Ornithorhynchus anatinus	92.29	0.00e+00	5202.00
IUUC-Ocu-074032	Oryctolagus cuniculus	91.69	0.00e+00	7618.00
IUUC-Ola-087433	Oryzias latipes	83.03	0.00e+00	1577.00
IUUC-Oga-088546	Otolemur garnettii	92.91	0.00e+00	6627.00
IUUC-Oar-089643	Ovis aries	87.47	0.00e+00	713.00
IUUC-Ptr-090504	Pan troglodytes	91.95	0.00e+00	6923.00
IUUC-Pan-092543	Papio anubis	93.10	0.00e+00	7562.00
IUUC-Psi-093952	Pelodiscus sinensis	92.07	0.00e+00	7015.00
IUUC-Pfo-096356	Poecilia formosa	83.68	0.00e+00	5194.00
IUUC-Pab-098240	Pongo abelii	93.12	0.00e+00	7635.00
IUUC-Pca-100994	Procavia capensis	94.73	0.00e+00	2926.00
IUUC-Pva-102263	Pteropus vampyrus	91.41	0.00e+00	6824.00
IUUC-Rno-104888	Rattus norvegicus	91.58	0.00e+00	7135.00
IUUC-Sha-106944	Sarcophilus harrisii	91.77	0.00e+00	7016.00
IUUC-Sar-113556	Sorex araneus	83.18	0.00e+00	913.00
IUUC-Ssc-116187	Sus scrofa	92.77	0.00e+00	4920.00
IUUC-Tgu-116655	Taeniopygia guttata	97.67	0.00e+00	5384.00
IUUC-Tru-118093	Takifugu rubripes	83.78	0.00e+00	3025.00
IUUC-Tni-119739	Tetraodon nigroviridis	83.35	0.00e+00	1612.00
IUUC-Tbe-127962	Tupaia belangeri	84.53	0.00e+00	1090.00
IUUC-Ttr-128819	Tursiops truncatus	87.41	0.00e+00	2675.00
IUUC-Vpa-130482	Vicugna pacos	91.20	0.00e+00	4331.00
IUUC-Xtr-132222	Xenopus tropicalis	87.61	0.00e+00	6646.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence