iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055032

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03000164

Gene Name

KLHL21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000018181.3	ENSMMUT00000025554.3	ENSMMUP00000023910.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.50e-19	70.0	36	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.60e-09	35.5	136	164

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    Dvilvvg.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           Dv+l+ + g+ f+ah++vLaa+S++F+a+f ++l+es+  ++v +++v p+ ++ ll+F+Ytg++ 
   Q: 36   DVTLEAAgGRDFPAHRAVLAAASPYFRAMFAGQLRESR-AERVRLHGVPPDMLQLLLDFSYTGRVA 100
           9*****99******************************.************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkh 30
            Ncl++ +fA++++c+ L++aa++fil+h
   Q: 136  ANCLDMQDFAEAFSCSGLASAAQRFILRH 164
           6***************************9 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MERPAPLAVL PFSDPAHALS LLRGLSQLRA ERKFLDVTLE AAGGRDFPAH RAVLAAASPY 60
FRAMFAGQLR ESRAERVRLH GVPPDMLQLL LDFSYTGRVA VSGDNAEPLL RAADLLQFPA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCGGC CGGCTCCGCT AGCCGTGCTG CCCTTCTCGG ACCCCGCGCA CGCCCTGAGC 60
CTGCTGCGCG GCCTGAGCCA GCTCCGCGCC GAGCGCAAGT TCCTGGACGT GACCCTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005827--C:polar microtubule
GO:0004842--F:ubiquitin-protein transferase activity
GO:0035853--P:chromosome passenger complex localization to spindle midzone
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001782	Ailuropoda melanoleuca	88.06	0.00e+00	754.00
IUUC-Apl-003189	Anas platyrhynchos	87.23	1.00e-102	365.00
IUUC-Ame-011774	Astyanax mexicanus	66.11	1.00e-136	479.00
IUUC-Bta-012367	Bos taurus	98.80	0.00e+00	979.00
IUUC-Cja-019501	Callithrix jacchus	90.54	0.00e+00	868.00
IUUC-Cfa-020550	Canis familiaris	99.00	0.00e+00	982.00
IUUC-Cpo-022072	Cavia porcellus	98.40	0.00e+00	961.00
IUUC-Csa-023364	Chlorocebus sabaeus	100.00	0.00e+00	869.00
IUUC-Cin-025253	Ciona intestinalis	41.68	4.00e-122	431.00
IUUC-Csv-025871	Ciona savignyi	43.98	2.00e-129	456.00
IUUC-Dre-028694	Danio rerio	71.43	0.00e+00	743.00
IUUC-Dno-029082	Dasypus novemcinctus	95.67	0.00e+00	786.00
IUUC-Dor-030680	Dipodomys ordii	98.20	0.00e+00	973.00
IUUC-Ete-032315	Echinops telfairi	97.80	0.00e+00	799.00
IUUC-Eca-033570	Equus caballus	97.24	5.00e-150	523.00
IUUC-Eeu-035067	Erinaceus europaeus	98.56	1.00e-105	376.00
IUUC-Fal-037103	Ficedula albicollis	84.63	0.00e+00	771.00
IUUC-Gmo-039420	Gadus morhua	68.65	0.00e+00	716.00
IUUC-Ggr-039811	Gaeumannomyces graminis	38.36	3.00e-08	52.80
IUUC-Gga-040161	Gallus gallus	83.85	0.00e+00	736.00
IUUC-Gac-041755	Gasterosteus aculeatus	70.83	0.00e+00	739.00
IUUC-Ggo-044899	Gorilla gorilla	99.40	0.00e+00	985.00
IUUC-Hsa-045834	Homo sapiens	99.60	0.00e+00	987.00
IUUC-Itr-048413	Ictidomys tridecemlineatus	99.00	0.00e+00	981.00
IUUC-Lch-050338	Latimeria chalumnae	70.04	0.00e+00	748.00
IUUC-Loc-051780	Lepisosteus oculatus	74.01	0.00e+00	760.00
IUUC-Laf-053725	Loxodonta africana	98.02	0.00e+00	628.00
IUUC-Meu-056661	Macropus eugenii	96.13	0.00e+00	630.00
IUUC-Mpo-057626	Magnaporthe poae	31.67	3.00e-07	50.10
IUUC-Mga-059821	Meleagris gallopavo	88.12	4.00e-87	314.00
IUUC-Mdo-062095	Monodelphis domestica	95.20	0.00e+00	947.00
IUUC-Mmu-063138	Mus musculus	98.80	0.00e+00	979.00
IUUC-Mpu-066386	Mustela putorius furo	98.67	5.00e-134	470.00
IUUC-Mlu-067807	Myotis lucifugus	98.45	1.00e-153	535.00
IUUC-Nle-069181	Nomascus leucogenys	98.60	0.00e+00	970.00
IUUC-Opr-070658	Ochotona princeps	98.60	0.00e+00	1003.00
IUUC-Ont-072209	Oreochromis niloticus	69.84	0.00e+00	731.00
IUUC-Ocu-074631	Oryctolagus cuniculus	86.93	0.00e+00	825.00
IUUC-Ola-087553	Oryzias latipes	68.06	0.00e+00	714.00
IUUC-Oga-088782	Otolemur garnettii	98.80	0.00e+00	980.00
IUUC-Oar-089634	Ovis aries	98.40	0.00e+00	975.00
IUUC-Ptr-091259	Pan troglodytes	99.43	0.00e+00	691.00
IUUC-Pan-091734	Papio anubis	99.80	0.00e+00	989.00
IUUC-Psi-092979	Pelodiscus sinensis	82.82	0.00e+00	788.00
IUUC-Pma-094459	Petromyzon marinus	53.17	3.00e-124	438.00
IUUC-Pfo-097446	Poecilia formosa	70.04	0.00e+00	733.00
IUUC-Pab-098765	Pongo abelii	99.80	0.00e+00	986.00
IUUC-Pca-101018	Procavia capensis	99.42	5.00e-94	338.00
IUUC-Pva-102730	Pteropus vampyrus	94.60	0.00e+00	928.00
IUUC-Rno-104972	Rattus norvegicus	98.60	0.00e+00	981.00
IUUC-Ssc-115869	Sus scrofa	98.60	0.00e+00	978.00
IUUC-Tgu-116562	Taeniopygia guttata	84.47	0.00e+00	803.00
IUUC-Tru-118490	Takifugu rubripes	69.25	0.00e+00	724.00
IUUC-Tni-119898	Tetraodon nigroviridis	67.26	0.00e+00	694.00
IUUC-Ttr-128976	Tursiops truncatus	97.48	4.00e-93	335.00
IUUC-Xtr-132876	Xenopus tropicalis	73.29	0.00e+00	776.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence