iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-068105

Ensembl Protein ID

ENSMLUP00000006508.2

UniProt Accession

G1P8J9; G1P8J9_MYOLU

Genbank Protein ID

ENSMLUP00000006508

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02029506

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000007129.2	ENSMLUT00000007131.2	ENSMLUP00000006508.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	81.30	0.00e+00	769.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MASLSTSAQC STTDSACRSS PRQIKQQVRP KPPLLKILQA AGAQGEIFTV TQVMHFLGQY 60
ITMKQLYDPR EQHMVYCSGD LLGELLGCQS FSVKDPSPLY AMLRKNLVAL TIAAADAAQT 120

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Nucleotide Sequence
(Fasta)

ATGGCATCAC TTTCTACCTC TGCCCAGTGT TCAACAACTG ACAGTGCTTG CAGGAGCTCT 60
CCAAGACAGA TCAAGCAGGT AAGATGTTTT TAGGCATTCC TATTTCTCTT TAAGTTAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	82.76	0.00e+00	740.00
IUUC-Apl-003800	Anas platyrhynchos	55.42	6.00e-136	477.00
IUUC-Aca-004608	Anolis carolinensis	54.03	5.00e-135	474.00
IUUC-Ame-010869	Astyanax mexicanus	44.78	1.00e-102	367.00
IUUC-Bta-013287	Bos taurus	80.49	0.00e+00	785.00
IUUC-Cja-019305	Callithrix jacchus	79.47	0.00e+00	714.00
IUUC-Cfa-020393	Canis familiaris	82.56	0.00e+00	758.00
IUUC-Cpo-022166	Cavia porcellus	78.11	0.00e+00	685.00
IUUC-Csa-023654	Chlorocebus sabaeus	80.49	0.00e+00	719.00
IUUC-Cho-024403	Choloepus hoffmanni	80.52	9.00e-115	406.00
IUUC-Csv-026151	Ciona savignyi	38.46	1.00e-13	70.10
IUUC-Dre-027754	Danio rerio	43.70	2.00e-109	389.00
IUUC-Dno-029630	Dasypus novemcinctus	77.69	0.00e+00	743.00
IUUC-Dor-031064	Dipodomys ordii	62.20	3.00e-167	581.00
IUUC-Ete-032901	Echinops telfairi	70.79	0.00e+00	696.00
IUUC-Eca-034234	Equus caballus	83.13	0.00e+00	839.00
IUUC-Eeu-035015	Erinaceus europaeus	61.87	2.00e-155	541.00
IUUC-Fca-036587	Felis catus	82.72	0.00e+00	775.00
IUUC-Fal-036906	Ficedula albicollis	49.59	8.00e-130	456.00
IUUC-Gmo-038646	Gadus morhua	39.72	3.00e-87	315.00
IUUC-Gga-040124	Gallus gallus	55.13	3.00e-105	374.00
IUUC-Gac-042397	Gasterosteus aculeatus	41.96	4.00e-99	355.00
IUUC-Ggo-045505	Gorilla gorilla	81.10	0.00e+00	744.00
IUUC-Hsa-046950	Homo sapiens	81.30	0.00e+00	747.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	79.27	0.00e+00	746.00
IUUC-Lch-050141	Latimeria chalumnae	50.20	2.00e-116	412.00
IUUC-Loc-051921	Lepisosteus oculatus	45.54	1.00e-105	376.00
IUUC-Laf-054281	Loxodonta africana	77.24	0.00e+00	715.00
IUUC-Mcc-055462	Macaca mulatta	77.44	0.00e+00	678.00
IUUC-Meu-056294	Macropus eugenii	64.36	6.00e-127	447.00
IUUC-Mga-059924	Meleagris gallopavo	55.51	4.00e-149	521.00
IUUC-Mmr-061428	Microcebus murinus	78.66	0.00e+00	766.00
IUUC-Mdo-062643	Monodelphis domestica	68.47	0.00e+00	657.00
IUUC-Mmu-063229	Mus musculus	74.19	0.00e+00	689.00
IUUC-Mpu-065782	Mustela putorius furo	81.17	0.00e+00	752.00
IUUC-Nle-069549	Nomascus leucogenys	81.30	0.00e+00	748.00
IUUC-Opr-070568	Ochotona princeps	79.57	0.00e+00	712.00
IUUC-Ont-072276	Oreochromis niloticus	43.88	3.00e-111	395.00
IUUC-Oan-072787	Ornithorhynchus anatinus	68.09	5.00e-175	607.00
IUUC-Ocu-074912	Oryctolagus cuniculus	78.86	0.00e+00	745.00
IUUC-Ola-087037	Oryzias latipes	41.65	1.00e-91	330.00
IUUC-Oga-088953	Otolemur garnettii	77.22	0.00e+00	709.00
IUUC-Oar-089202	Ovis aries	80.49	0.00e+00	790.00
IUUC-Ptr-090964	Pan troglodytes	81.50	0.00e+00	749.00
IUUC-Pan-091975	Papio anubis	80.28	0.00e+00	735.00
IUUC-Psi-093558	Pelodiscus sinensis	56.56	3.00e-145	508.00
IUUC-Pfo-096454	Poecilia formosa	44.02	7.00e-104	370.00
IUUC-Pab-098123	Pongo abelii	80.69	0.00e+00	743.00
IUUC-Pca-101112	Procavia capensis	70.39	0.00e+00	668.00
IUUC-Pva-103098	Pteropus vampyrus	82.11	0.00e+00	775.00
IUUC-Rno-105930	Rattus norvegicus	75.20	0.00e+00	684.00
IUUC-Sha-107512	Sarcophilus harrisii	65.92	1.00e-161	563.00
IUUC-Sar-113584	Sorex araneus	74.63	0.00e+00	666.00
IUUC-Tgu-116766	Taeniopygia guttata	52.98	4.00e-93	334.00
IUUC-Tru-117829	Takifugu rubripes	43.56	1.00e-107	383.00
IUUC-Tsy-119268	Tarsius syrichta	67.68	2.00e-172	598.00
IUUC-Tni-120204	Tetraodon nigroviridis	42.68	5.00e-100	358.00
IUUC-Tbe-127840	Tupaia belangeri	74.76	4.00e-109	388.00
IUUC-Ttr-128863	Tursiops truncatus	79.47	0.00e+00	758.00
IUUC-Vpa-130718	Vicugna pacos	83.66	0.00e+00	761.00
IUUC-Xtr-132320	Xenopus tropicalis	43.57	4.00e-85	308.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence