iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072787

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPN01212215

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000013464.2	ENSOANT00000021250.2	ENSOANP00000021247.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	73.29	0.00e+00	649.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

VRPKLPLLKI LQAAGAQGEI FTVKEVMHFL GQYIMVKQLY DQQAQHMVHC GGDLLGELLG 60
LQSFSVKDPS PLYEMLRKNL VSTTVPVSHA AQTLAQEQSM DIPSQDQLKQ NAEESASPRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTACGGCCAA AATTGCCACT TCTGAAGATT TTGCAGGCAG CTGGAGCACA AGGTGAAATC 60
TTCACAGTGA AGGAGGTAAA CCAGGATGTG TTATACATTA GTCTCTAGAC TGTAAACTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	73.77	4.00e-168	583.00
IUUC-Apl-003800	Anas platyrhynchos	64.09	5.00e-151	526.00
IUUC-Aca-004608	Anolis carolinensis	54.84	1.00e-125	442.00
IUUC-Ame-010869	Astyanax mexicanus	48.96	3.00e-105	374.00
IUUC-Bta-013287	Bos taurus	73.08	0.00e+00	646.00
IUUC-Cja-019305	Callithrix jacchus	71.95	9.00e-170	589.00
IUUC-Cfa-020393	Canis familiaris	73.40	5.00e-174	603.00
IUUC-Cpo-022166	Cavia porcellus	71.52	3.00e-170	590.00
IUUC-Csa-023654	Chlorocebus sabaeus	72.59	3.00e-166	577.00
IUUC-Cho-024403	Choloepus hoffmanni	69.03	9.00e-92	329.00
IUUC-Dre-027754	Danio rerio	50.10	6.00e-115	407.00
IUUC-Dno-029630	Dasypus novemcinctus	73.13	2.00e-180	624.00
IUUC-Dor-031064	Dipodomys ordii	54.72	4.00e-137	480.00
IUUC-Ete-032901	Echinops telfairi	65.81	5.00e-169	586.00
IUUC-Eca-034234	Equus caballus	74.15	0.00e+00	673.00
IUUC-Eeu-035015	Erinaceus europaeus	54.49	4.00e-121	427.00
IUUC-Fca-036587	Felis catus	73.93	3.00e-180	624.00
IUUC-Fal-036906	Ficedula albicollis	56.96	5.00e-138	483.00
IUUC-Gmo-038646	Gadus morhua	46.36	5.00e-96	344.00
IUUC-Gga-040124	Gallus gallus	63.80	1.00e-119	421.00
IUUC-Gac-042397	Gasterosteus aculeatus	48.97	3.00e-112	397.00
IUUC-Ggo-045505	Gorilla gorilla	73.02	8.00e-173	599.00
IUUC-Hsa-046950	Homo sapiens	73.08	1.00e-173	601.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	72.16	7.00e-174	602.00
IUUC-Lch-050141	Latimeria chalumnae	56.54	2.00e-127	448.00
IUUC-Loc-051921	Lepisosteus oculatus	50.84	4.00e-112	397.00
IUUC-Laf-054281	Loxodonta africana	72.86	6.00e-179	619.00
IUUC-Mcc-055462	Macaca mulatta	69.46	2.00e-153	534.00
IUUC-Meu-056294	Macropus eugenii	73.30	1.00e-135	475.00
IUUC-Mga-059924	Meleagris gallopavo	63.03	9.00e-163	565.00
IUUC-Mmr-061428	Microcebus murinus	72.86	0.00e+00	640.00
IUUC-Mdo-062643	Monodelphis domestica	75.74	0.00e+00	692.00
IUUC-Mmu-063229	Mus musculus	69.38	2.00e-174	605.00
IUUC-Mpu-065782	Mustela putorius furo	72.55	2.00e-172	598.00
IUUC-Mlu-068105	Myotis lucifugus	67.88	3.00e-170	590.00
IUUC-Nle-069549	Nomascus leucogenys	73.23	1.00e-173	602.00
IUUC-Opr-070568	Ochotona princeps	71.52	3.00e-177	613.00
IUUC-Ont-072276	Oreochromis niloticus	48.67	5.00e-116	410.00
IUUC-Ocu-074912	Oryctolagus cuniculus	72.59	1.00e-180	625.00
IUUC-Ola-087037	Oryzias latipes	47.46	4.00e-105	374.00
IUUC-Oga-088953	Otolemur garnettii	70.85	1.00e-174	605.00
IUUC-Oar-089202	Ovis aries	73.08	0.00e+00	649.00
IUUC-Ptr-090964	Pan troglodytes	73.02	6.00e-173	599.00
IUUC-Pan-091975	Papio anubis	72.44	1.00e-170	592.00
IUUC-Psi-093558	Pelodiscus sinensis	63.95	4.00e-154	536.00
IUUC-Pfo-096454	Poecilia formosa	48.66	1.00e-114	406.00
IUUC-Pab-098123	Pongo abelii	73.02	1.00e-173	602.00
IUUC-Pca-101112	Procavia capensis	65.10	1.00e-158	552.00
IUUC-Ppe-101490	Prunus persica	32.26	5.00e-09	55.10
IUUC-Pva-103098	Pteropus vampyrus	67.02	5.00e-167	580.00
IUUC-Rno-105930	Rattus norvegicus	69.72	1.00e-173	602.00
IUUC-Sha-107512	Sarcophilus harrisii	74.79	3.00e-175	607.00
IUUC-Smo-108729	Selaginella moellendorffii	44.74	4.00e-07	49.70
IUUC-Sar-113584	Sorex araneus	63.81	1.00e-155	542.00
IUUC-Tgu-116766	Taeniopygia guttata	59.50	1.00e-104	372.00
IUUC-Tru-117829	Takifugu rubripes	49.17	8.00e-116	409.00
IUUC-Tsy-119268	Tarsius syrichta	69.23	9.00e-82	296.00
IUUC-Tni-120204	Tetraodon nigroviridis	48.36	3.00e-110	391.00
IUUC-Tbe-127840	Tupaia belangeri	68.91	1.00e-95	342.00
IUUC-Ttr-128863	Tursiops truncatus	71.37	7.00e-178	616.00
IUUC-Vpa-130718	Vicugna pacos	72.81	2.00e-180	624.00
IUUC-Xtr-132320	Xenopus tropicalis	48.87	3.00e-92	331.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence