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Tag Content
iUUCD ID IUUC-Lch-050569
Ensembl Protein ID ENSLACP00000019047.1
UniProt Accession H3BAX6; H3BAX6_LATCH
Genbank Protein ID ENSLACP00000019047
Protein Name Nitric oxide synthase-interacting protein
Genbank Nucleotide ID AFYH01030478
Gene Name NOSIP
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSLACG00000016760.2 ENSLACT00000019179.2 ENSLACP00000019046.2
ENSLACG00000016760.2 ENSLACT00000019180.1 ENSLACP00000019047.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 1.20e-14 54.3 47 98
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqpltee 53
           + ++ +C++sl++ +dPvv+p G+ y++++I +++ +++++  + ++ ++++
   Q: 47   IKDFDCCSLSLQPCKDPVVTPEGYLYEKEAILEYILHQKREIAKKMKAFEKQ 98
           677889*****************************99998555555555444 PP
   
Organism Latimeria chalumnae
Functional Description
(View)

Functional Description


     Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.
 Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.
Protein Sequence
(Fasta)
MTRHGKNCTA GAVYTYYEKR KDTEIYVSGV AASGYGTQSA RLSKDSIKDF DCCSLSLQPC 60
KDPVVTPEGY LYEKEAILEY ILHQKREIAK KMKAFEKQKN EKKAEAQELV KAAKDTKVKA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Lch-050569|E3,U-box|Latimeria chalumnae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCTAGGAACT GTGGTGTCTC TGCTGTGTGT TTCTCAGGCT GTTATTCCTG TTGCACCAGC 60
CCCACTTGCT TTGTTTTTCG TCTGATGGAG CTGTTCTGGT CAGTTTCTGG GCTTCTGATC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Lch-050569|E3,U-box|Latimeria chalumnae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
Interpro

IPR016818--Nitric_oxide_synth-interacting
IPR003613--Ubox_domain
IPR031790--Znf-NOSIP
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51698--U_BOX
Pfam

PF15906--zf-NOSIP
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0050999--P:regulation of nitric-oxide synthase activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000769 Aegilops tauschii 46.24 5.00e-16 79.30
IUUC-Aml-002069 Ailuropoda melanoleuca 64.51 9.00e-119 419.00
IUUC-Atr-002661 Amborella trichopoda 32.34 3.00e-30 125.00
IUUC-Aca-004630 Anolis carolinensis 74.35 3.00e-130 457.00
IUUC-Aly-006316 Arabidopsis lyrata 29.55 4.00e-27 115.00
IUUC-Ath-007000 Arabidopsis thaliana 28.57 2.00e-26 112.00
IUUC-Acl-008175 Aspergillus clavatus 33.33 2.00e-05 43.10
IUUC-Afl-008440 Aspergillus flavus 23.55 3.00e-09 55.80
IUUC-Afu-009012 Aspergillus fumigatus 32.56 3.00e-06 46.20
IUUC-Ang-009556 Aspergillus niger 22.51 9.00e-08 51.20
IUUC-Aor-009892 Aspergillus oryzae 23.55 5.00e-08 52.00
IUUC-Ate-010473 Aspergillus terreus 29.91 2.00e-06 48.10
IUUC-Ame-011874 Astyanax mexicanus 63.29 6.00e-108 383.00
IUUC-Bgr-012090 Blumeria graminis 27.05 3.00e-07 48.90
IUUC-Bta-012956 Bos taurus 68.27 1.00e-125 442.00
IUUC-Bci-013897 Botrytis cinerea 36.78 2.00e-09 56.60
IUUC-Bdi-014968 Brachypodium distachyon 32.66 5.00e-32 131.00
IUUC-Bol-015578 Brassica oleracea 29.22 3.00e-32 132.00
IUUC-Bra-017234 Brassica rapa 29.22 3.00e-32 132.00
IUUC-Cel-018637 Caenorhabditis elegans 45.45 3.00e-55 208.00
IUUC-Cja-019632 Callithrix jacchus 68.28 7.00e-125 439.00
IUUC-Cfa-020192 Canis familiaris 66.99 2.00e-122 432.00
IUUC-Cpo-021939 Cavia porcellus 67.10 4.00e-120 424.00
IUUC-Cre-023005 Chlamydomonas reinhardtii 36.24 4.00e-40 158.00
IUUC-Csa-023802 Chlorocebus sabaeus 68.93 4.00e-125 440.00
IUUC-Cho-024637 Choloepus hoffmanni 56.79 5.00e-47 180.00
IUUC-Cin-025180 Ciona intestinalis 55.99 1.00e-92 332.00
IUUC-Csv-026206 Ciona savignyi 52.66 8.00e-50 189.00
IUUC-Cgl-026696 Colletotrichum gloeosporioides 23.91 7.00e-12 64.70
IUUC-Cne-026827 Cryptococcus neoformans 27.43 1.00e-09 57.40
IUUC-Dre-028092 Danio rerio 68.49 2.00e-119 421.00
IUUC-Dno-029501 Dasypus novemcinctus 63.23 2.00e-104 372.00
IUUC-Dor-030542 Dipodomys ordii 65.61 9.00e-122 429.00
IUUC-Dse-031188 Dothistroma septosporum 21.04 1.00e-09 57.40
IUUC-Dme-031734 Drosophila melanogaster 46.50 4.00e-81 294.00
IUUC-Eca-033577 Equus caballus 67.95 4.00e-124 437.00
IUUC-Fca-035761 Felis catus 67.95 4.00e-124 437.00
IUUC-Fox-037703 Fusarium oxysporum 25.77 8.00e-16 77.80
IUUC-Fso-038208 Fusarium solani 25.71 3.00e-14 72.80
IUUC-Gmo-038523 Gadus morhua 56.16 9.00e-56 209.00
IUUC-Ggr-040087 Gaeumannomyces graminis 38.82 8.00e-11 61.20
IUUC-Gac-042621 Gasterosteus aculeatus 60.24 3.00e-107 381.00
IUUC-Gma-042698 Glycine max 32.01 4.00e-32 131.00
IUUC-Ggo-045357 Gorilla gorilla 68.93 4.00e-125 440.00
IUUC-Hsa-046195 Homo sapiens 68.93 4.00e-125 440.00
IUUC-Hvu-047174 Hordeum vulgare 31.99 4.00e-32 131.00
IUUC-Itr-048487 Ictidomys tridecemlineatus 66.56 4.00e-121 427.00
IUUC-Lpe-050992 Leersia perrieri 37.02 3.00e-22 99.40
IUUC-Loc-052522 Lepisosteus oculatus 69.06 1.00e-115 409.00
IUUC-Lma-053254 Leptosphaeria maculans 24.14 2.00e-11 63.20
IUUC-Laf-053397 Loxodonta africana 65.81 7.00e-121 426.00
IUUC-Mcc-054681 Macaca mulatta 69.26 5.00e-126 443.00
IUUC-Meu-056723 Macropus eugenii 65.26 3.00e-119 421.00
IUUC-Mor-056961 Magnaporthe oryzae 29.55 2.00e-11 63.50
IUUC-Mpo-057359 Magnaporthe poae 25.00 1.00e-03 37.00
IUUC-Mtr-058063 Medicago truncatula 31.68 2.00e-32 132.00
IUUC-Mla-059004 Melampsora laricipopulina 27.52 3.00e-24 105.00
IUUC-Mvi-060460 Microbotryum violaceum 27.54 4.00e-23 101.00
IUUC-Mmr-060847 Microcebus murinus 68.27 2.00e-124 437.00
IUUC-Mdo-062480 Monodelphis domestica 65.70 2.00e-119 421.00
IUUC-Mmu-063809 Mus musculus 66.67 4.00e-120 424.00
IUUC-Mac-064870 Musa acuminata 31.68 7.00e-34 137.00
IUUC-Mpu-066322 Mustela putorius furo 67.52 1.00e-123 436.00
IUUC-Mlu-067556 Myotis lucifugus 64.95 4.00e-119 420.00
IUUC-Nfi-068440 Neosartorya fischeri 23.51 2.00e-10 59.70
IUUC-Ncr-068898 Neurospora crassa 35.29 6.00e-08 51.60
IUUC-Nle-070049 Nomascus leucogenys 69.26 2.00e-125 441.00
IUUC-Opr-070972 Ochotona princeps 64.86 3.00e-119 421.00
IUUC-Ont-071682 Oreochromis niloticus 66.13 8.00e-114 402.00
IUUC-Oan-073296 Ornithorhynchus anatinus 75.76 1.00e-25 108.00
IUUC-Ocu-074218 Oryctolagus cuniculus 65.62 2.00e-103 368.00
IUUC-Oba-075284 Oryza barthii 32.78 9.00e-32 130.00
IUUC-Obr-076651 Oryza brachyantha 32.78 3.00e-34 138.00
IUUC-Ogl-077899 Oryza glaberrima 32.78 9.00e-32 130.00
IUUC-Ogu-078477 Oryza glumaepatula 32.78 2.00e-31 129.00
IUUC-Oin-080011 Oryza indica 32.78 9.00e-32 130.00
IUUC-Olo-080545 Oryza longistaminata 33.08 4.00e-25 108.00
IUUC-Ome-081543 Oryza meridionalis 32.78 9.00e-32 130.00
IUUC-Oni-082955 Oryza nivara 32.78 9.00e-32 130.00
IUUC-Opu-083565 Oryza punctata 32.78 4.00e-32 131.00
IUUC-Oru-084474 Oryza rufipogon 32.78 9.00e-32 130.00
IUUC-Osa-085913 Oryza sativa 32.78 9.00e-32 130.00
IUUC-Ola-086851 Oryzias latipes 65.58 1.00e-116 412.00
IUUC-Olu-087724 Ostreococcus lucimarinus 34.31 5.00e-12 65.10
IUUC-Oga-087970 Otolemur garnettii 69.23 2.00e-125 441.00
IUUC-Oar-089756 Ovis aries 66.03 9.00e-117 412.00
IUUC-Ptr-091485 Pan troglodytes 67.96 1.00e-121 428.00
IUUC-Pan-091832 Papio anubis 69.26 1.00e-125 442.00
IUUC-Pma-094551 Petromyzon marinus 66.88 1.00e-111 395.00
IUUC-Ppa-095255 Physcomitrella patens 30.36 6.00e-30 124.00
IUUC-Pfo-096373 Poecilia formosa 66.13 7.00e-116 409.00
IUUC-Pab-098247 Pongo abelii 68.93 5.00e-125 440.00
IUUC-Pop-099186 Populus trichocarpa 31.68 6.00e-30 124.00
IUUC-Pca-100677 Procavia capensis 65.82 4.00e-100 357.00
IUUC-Ppe-101403 Prunus persica 29.04 6.00e-28 117.00
IUUC-Pva-103000 Pteropus vampyrus 68.06 2.00e-123 434.00
IUUC-Pgr-103663 Puccinia graminis 27.83 6.00e-29 121.00
IUUC-Ptt-103712 Puccinia triticina 38.46 3.00e-10 58.50
IUUC-Pte-104287 Pyrenophora teres 25.61 8.00e-14 71.20
IUUC-Pyt-104579 Pyrenophora triticirepentis 24.75 9.00e-11 60.80
IUUC-Rno-106069 Rattus norvegicus 66.99 7.00e-121 426.00
IUUC-Sha-106553 Sarcophilus harrisii 65.58 1.00e-119 422.00
IUUC-Smo-108874 Selaginella moellendorffii 32.89 2.00e-36 145.00
IUUC-Sit-110307 Setaria italica 33.11 1.00e-31 129.00
IUUC-Sly-111094 Solanum lycopersicum 31.02 4.00e-30 124.00
IUUC-Stu-112363 Solanum tuberosum 31.02 4.00e-30 125.00
IUUC-Sar-113480 Sorex araneus 66.02 1.00e-116 412.00
IUUC-Sbi-113939 Sorghum bicolor 32.78 2.00e-31 129.00
IUUC-Ssc-115644 Sus scrofa 68.27 1.00e-124 439.00
IUUC-Tru-118781 Takifugu rubripes 66.77 1.00e-118 419.00
IUUC-Tni-119672 Tetraodon nigroviridis 74.71 1.00e-34 136.00
IUUC-Tca-121795 Theobroma cacao 31.35 5.00e-33 134.00
IUUC-Tre-122037 Trichoderma reesei 35.71 1.00e-09 57.00
IUUC-Tvi-122524 Trichoderma virens 25.34 4.00e-15 75.50
IUUC-Tae-122828 Triticum aestivum 32.32 3.00e-32 132.00
IUUC-Tur-126387 Triticum urartu 31.94 1.00e-25 110.00
IUUC-Tme-127111 Tuber melanosporum 37.36 1.00e-10 60.50
IUUC-Ttr-128227 Tursiops truncatus 67.63 2.00e-123 434.00
IUUC-Vda-129924 Verticillium dahliae 26.53 9.00e-15 74.30
IUUC-Vpa-130802 Vicugna pacos 74.16 3.00e-35 141.00
IUUC-Vvi-131105 Vitis vinifera 31.02 2.00e-30 126.00
IUUC-Xtr-132830 Xenopus tropicalis 68.71 2.00e-130 458.00
IUUC-Xma-133618 Xiphophorus maculatus 65.27 1.00e-108 385.00
IUUC-Zma-135389 Zea mays 32.89 4.00e-31 128.00
Created Date 25-Jun-2017

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