iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052522

Ensembl Protein ID

ENSLOCP00000021225.1

UniProt Accession

W5NKR6; W5NKR6_LEPOC

Genbank Protein ID

ENSLOCP00000021225

Protein Name

Nitric oxide synthase-interacting protein

Genbank Nucleotide ID

AHAT01037776

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000017172.1	ENSLOCT00000021261.1	ENSLOCP00000021225.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	7.10e-14	51.8	40	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggkt 42
           + ++ +C +sl++ rdPvv+p+G+ y+r++I +++ +++++
   Q: 40   IKDFDCCCLSLQPCRDPVVTPDGYLYEREAILEYILHQKTE 80
           567789*****************************998873 PP

Organism

Lepisosteus oculatus

Functional Description
(View)

Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.

Protein Sequence
(Fasta)

MTRHGKNCTA GAVYTYHEKK KDTAASGYGT QSVRLGKDAI KDFDCCCLSL QPCRDPVVTP 60
DGYLYEREAI LEYILHQKTE IAKKMKAYEK QKRAQASEEK LLSRASEDSK VKSFLQKEGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACACTCACA CACTCACACA CCCACAGCCA CACTCTCACA CACACACGCT CACACACACA 60
CACACTGCCA CACTCTTACA CACACACGCT CAAACACCCA CCCACTGCCA CACTCTCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR016818--Nitric_oxide_synth-interacting
IPR031790--Znf-NOSIP
IPR013083--Znf_RING/FYVE/PHD

Pfam

PF15906--zf-NOSIP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0050999--P:regulation of nitric-oxide synthase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000769	Aegilops tauschii	47.67	9.00e-17	81.60
IUUC-Aml-002069	Ailuropoda melanoleuca	66.04	2.00e-121	428.00
IUUC-Atr-002661	Amborella trichopoda	30.38	1.00e-25	110.00
IUUC-Aca-004630	Anolis carolinensis	73.22	5.00e-124	436.00
IUUC-Aly-006316	Arabidopsis lyrata	31.44	6.00e-28	117.00
IUUC-Ath-007000	Arabidopsis thaliana	30.77	5.00e-27	114.00
IUUC-Acl-008175	Aspergillus clavatus	30.83	2.00e-05	43.10
IUUC-Afl-008440	Aspergillus flavus	33.04	2.00e-06	46.60
IUUC-Ani-009153	Aspergillus nidulans	31.82	2.00e-03	36.60
IUUC-Ang-009556	Aspergillus niger	33.04	4.00e-06	45.80
IUUC-Aor-009892	Aspergillus oryzae	33.04	2.00e-06	46.60
IUUC-Ate-010473	Aspergillus terreus	26.55	1.00e-04	42.00
IUUC-Ame-011874	Astyanax mexicanus	76.55	2.00e-124	438.00
IUUC-Bta-012956	Bos taurus	70.20	1.00e-124	439.00
IUUC-Bci-013897	Botrytis cinerea	40.00	3.00e-09	55.80
IUUC-Bdi-014968	Brachypodium distachyon	31.65	3.00e-32	132.00
IUUC-Bol-015578	Brassica oleracea	31.05	1.00e-31	129.00
IUUC-Bra-017234	Brassica rapa	31.05	1.00e-31	129.00
IUUC-Cel-018637	Caenorhabditis elegans	43.12	9.00e-57	213.00
IUUC-Cja-019632	Callithrix jacchus	68.51	1.00e-123	435.00
IUUC-Cfa-020192	Canis familiaris	70.10	2.00e-124	438.00
IUUC-Cpo-021939	Cavia porcellus	71.86	3.00e-126	444.00
IUUC-Cre-023005	Chlamydomonas reinhardtii	32.78	6.00e-38	150.00
IUUC-Csa-023802	Chlorocebus sabaeus	70.00	7.00e-124	436.00
IUUC-Cho-024637	Choloepus hoffmanni	48.85	6.00e-45	173.00
IUUC-Cin-025180	Ciona intestinalis	53.02	3.00e-87	314.00
IUUC-Csv-026206	Ciona savignyi	48.91	5.00e-45	173.00
IUUC-Cgl-026696	Colletotrichum gloeosporioides	32.80	6.00e-11	61.60
IUUC-Cne-026827	Cryptococcus neoformans	37.65	1.00e-07	50.40
IUUC-Dre-028092	Danio rerio	75.91	6.00e-130	456.00
IUUC-Dno-029501	Dasypus novemcinctus	64.90	7.00e-106	377.00
IUUC-Dor-030542	Dipodomys ordii	70.20	6.00e-125	439.00
IUUC-Dme-031734	Drosophila melanogaster	46.25	4.00e-80	291.00
IUUC-Eca-033577	Equus caballus	70.10	1.00e-125	442.00
IUUC-Fca-035761	Felis catus	68.93	7.00e-125	439.00
IUUC-Gmo-038523	Gadus morhua	65.10	2.00e-64	238.00
IUUC-Ggr-040087	Gaeumannomyces graminis	33.59	1.00e-10	60.50
IUUC-Gac-042621	Gasterosteus aculeatus	69.50	1.00e-120	425.00
IUUC-Gma-042698	Glycine max	30.10	3.00e-28	118.00
IUUC-Ggo-045357	Gorilla gorilla	69.67	1.00e-123	435.00
IUUC-Hsa-046195	Homo sapiens	69.67	1.00e-123	435.00
IUUC-Hvu-047174	Hordeum vulgare	31.62	8.00e-32	130.00
IUUC-Itr-048487	Ictidomys tridecemlineatus	70.33	1.00e-124	439.00
IUUC-Lch-050569	Latimeria chalumnae	69.38	4.00e-114	404.00
IUUC-Lpe-050992	Leersia perrieri	35.29	1.00e-20	94.40
IUUC-Lma-053254	Leptosphaeria maculans	23.15	3.00e-09	56.20
IUUC-Laf-053397	Loxodonta africana	69.87	5.00e-124	436.00
IUUC-Mcc-054681	Macaca mulatta	69.44	7.00e-124	436.00
IUUC-Meu-056723	Macropus eugenii	70.81	1.00e-125	442.00
IUUC-Mor-056961	Magnaporthe oryzae	38.00	3.00e-09	55.80
IUUC-Mpo-057359	Magnaporthe poae	28.65	3.00e-07	48.50
IUUC-Mtr-058063	Medicago truncatula	30.51	1.00e-29	123.00
IUUC-Mla-059004	Melampsora laricipopulina	28.34	3.00e-23	102.00
IUUC-Mvi-060460	Microbotryum violaceum	27.30	1.00e-23	103.00
IUUC-Mmr-060847	Microcebus murinus	70.00	8.00e-125	439.00
IUUC-Mdo-062480	Monodelphis domestica	69.33	1.00e-122	432.00
IUUC-Mmu-063809	Mus musculus	70.00	3.00e-124	437.00
IUUC-Mac-064870	Musa acuminata	29.97	2.00e-30	126.00
IUUC-Mpu-066322	Mustela putorius furo	70.30	3.00e-125	441.00
IUUC-Mlu-067556	Myotis lucifugus	69.31	1.00e-124	439.00
IUUC-Ncr-068898	Neurospora crassa	35.90	9.00e-07	47.80
IUUC-Nle-070049	Nomascus leucogenys	69.67	1.00e-123	436.00
IUUC-Opr-070972	Ochotona princeps	69.97	3.00e-125	441.00
IUUC-Ont-071682	Oreochromis niloticus	74.83	5.00e-129	453.00
IUUC-Oan-073296	Ornithorhynchus anatinus	91.53	5.00e-30	123.00
IUUC-Ocu-074218	Oryctolagus cuniculus	70.00	2.00e-106	378.00
IUUC-Oba-075284	Oryza barthii	31.31	5.00e-30	124.00
IUUC-Obr-076651	Oryza brachyantha	31.31	6.00e-33	134.00
IUUC-Ogl-077899	Oryza glaberrima	31.31	5.00e-30	124.00
IUUC-Ogu-078477	Oryza glumaepatula	31.83	3.00e-30	125.00
IUUC-Oin-080011	Oryza indica	31.31	6.00e-30	124.00
IUUC-Olo-080545	Oryza longistaminata	31.66	2.00e-23	103.00
IUUC-Ome-081543	Oryza meridionalis	31.31	6.00e-30	124.00
IUUC-Oni-082955	Oryza nivara	31.31	6.00e-30	124.00
IUUC-Opu-083565	Oryza punctata	31.31	3.00e-30	125.00
IUUC-Oru-084474	Oryza rufipogon	31.31	6.00e-30	124.00
IUUC-Osa-085913	Oryza sativa	31.31	6.00e-30	124.00
IUUC-Ola-086851	Oryzias latipes	75.84	6.00e-132	462.00
IUUC-Olu-087724	Ostreococcus lucimarinus	31.07	1.00e-11	63.50
IUUC-Oga-087970	Otolemur garnettii	69.77	9.00e-123	432.00
IUUC-Oar-089756	Ovis aries	67.44	2.00e-115	408.00
IUUC-Ptr-091485	Pan troglodytes	68.33	4.00e-120	423.00
IUUC-Pan-091832	Papio anubis	69.67	1.00e-123	436.00
IUUC-Pma-094551	Petromyzon marinus	65.57	4.00e-109	387.00
IUUC-Ppa-095255	Physcomitrella patens	31.06	9.00e-27	113.00
IUUC-Pfo-096373	Poecilia formosa	74.75	4.00e-130	457.00
IUUC-Pab-098247	Pongo abelii	69.67	1.00e-123	435.00
IUUC-Pop-099186	Populus trichocarpa	30.64	6.00e-29	121.00
IUUC-Pca-100677	Procavia capensis	65.19	2.00e-97	348.00
IUUC-Ppe-101403	Prunus persica	29.90	2.00e-28	119.00
IUUC-Pva-103000	Pteropus vampyrus	70.10	4.00e-126	444.00
IUUC-Pgr-103663	Puccinia graminis	29.57	9.00e-29	120.00
IUUC-Ptt-103712	Puccinia triticina	36.92	3.00e-08	52.40
IUUC-Pte-104287	Pyrenophora teres	23.49	6.00e-12	65.10
IUUC-Pyt-104579	Pyrenophora triticirepentis	33.75	6.00e-08	51.60
IUUC-Rno-106069	Rattus norvegicus	70.33	1.00e-124	438.00
IUUC-Sha-106553	Sarcophilus harrisii	70.85	9.00e-126	442.00
IUUC-Smo-108874	Selaginella moellendorffii	30.61	8.00e-34	137.00
IUUC-Sit-110307	Setaria italica	31.99	1.00e-30	126.00
IUUC-Sly-111094	Solanum lycopersicum	30.10	4.00e-30	125.00
IUUC-Stu-112363	Solanum tuberosum	30.67	6.00e-30	124.00
IUUC-Sar-113480	Sorex araneus	69.80	1.00e-121	429.00
IUUC-Sbi-113939	Sorghum bicolor	31.99	4.00e-31	128.00
IUUC-Ssc-115644	Sus scrofa	70.00	2.00e-125	441.00
IUUC-Tru-118781	Takifugu rubripes	72.31	4.00e-128	450.00
IUUC-Tni-119672	Tetraodon nigroviridis	75.86	4.00e-35	138.00
IUUC-Tca-121795	Theobroma cacao	30.10	3.00e-31	129.00
IUUC-Tre-122037	Trichoderma reesei	35.06	3.00e-08	52.80
IUUC-Tvi-122524	Trichoderma virens	23.68	1.00e-13	70.50
IUUC-Tae-122828	Triticum aestivum	31.83	6.00e-32	130.00
IUUC-Tur-126387	Triticum urartu	31.62	2.00e-25	109.00
IUUC-Tme-127111	Tuber melanosporum	39.29	3.00e-09	56.20
IUUC-Ttr-128227	Tursiops truncatus	70.33	2.00e-125	441.00
IUUC-Vda-129924	Verticillium dahliae	26.39	2.00e-14	73.20
IUUC-Vpa-130802	Vicugna pacos	75.00	3.00e-35	142.00
IUUC-Vvi-131105	Vitis vinifera	29.97	1.00e-28	120.00
IUUC-Xtr-132830	Xenopus tropicalis	65.83	4.00e-118	417.00
IUUC-Xma-133618	Xiphophorus maculatus	73.93	9.00e-123	432.00
IUUC-Zma-135389	Zea mays	31.31	1.00e-29	123.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence