iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067556

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Nitric oxide synthase-interacting protein

Genbank Nucleotide ID

AAPE02059919

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000017657.2	ENSMLUT00000017661.2	ENSMLUP00000016105.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.70e-15	56.9	40	79

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk 41
           v ++ +C +sl++ +dPvv+p+G+ y+r++I +++ +++k
   Q: 40   VKDFDCCCLSLQPCHDPVVTPDGYLYEREAILEYILHQKK 79
           567789*****************************98887 PP

Organism

Myotis lucifugus

Functional Description
(View)

Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.

Protein Sequence
(Fasta)

MTRHGKNCTA GAVYTYHEKK KDTAASGYGT QNIRLSRDAV KDFDCCCLSL QPCHDPVVTP 60
DGYLYEREAI LEYILHQKKE IARQLKAYEK QRGARREERK ELQRAATQDQ VRGFLEKEAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGCGGC ACGGCAAGAA CTGCACGGCG GGGGCCGTCT ACACCTACCA CGAGAAGAAG 60
AAGGACACAG GTACTGGGTG GGAGGGGACA GATGCGTCTC GAAGCCACCG TCTCGCTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR016818--Nitric_oxide_synth-interacting
IPR031790--Znf-NOSIP
IPR013083--Znf_RING/FYVE/PHD

Pfam

PF15906--zf-NOSIP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0050999--P:regulation of nitric-oxide synthase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000769	Aegilops tauschii	46.51	2.00e-16	80.50
IUUC-Aml-002069	Ailuropoda melanoleuca	90.85	2.00e-162	564.00
IUUC-Atr-002661	Amborella trichopoda	31.86	3.00e-31	128.00
IUUC-Aca-004630	Anolis carolinensis	74.67	8.00e-136	476.00
IUUC-Aly-006316	Arabidopsis lyrata	31.07	3.00e-31	128.00
IUUC-Ath-007000	Arabidopsis thaliana	30.10	3.00e-30	125.00
IUUC-Ame-011874	Astyanax mexicanus	65.58	3.00e-111	394.00
IUUC-Bgr-012090	Blumeria graminis	25.44	1.00e-05	43.90
IUUC-Bta-012956	Bos taurus	95.41	2.00e-169	587.00
IUUC-Bci-013897	Botrytis cinerea	42.50	8.00e-10	57.80
IUUC-Bdi-014968	Brachypodium distachyon	29.97	3.00e-34	138.00
IUUC-Bol-015578	Brassica oleracea	30.94	2.00e-34	139.00
IUUC-Bra-017234	Brassica rapa	30.94	2.00e-34	139.00
IUUC-Cel-018637	Caenorhabditis elegans	41.69	2.00e-58	218.00
IUUC-Cja-019632	Callithrix jacchus	92.43	7.00e-167	579.00
IUUC-Cfa-020192	Canis familiaris	94.08	4.00e-167	580.00
IUUC-Cpo-021939	Cavia porcellus	89.47	6.00e-156	543.00
IUUC-Cre-023005	Chlamydomonas reinhardtii	33.77	3.00e-42	165.00
IUUC-Csa-023802	Chlorocebus sabaeus	92.76	7.00e-167	579.00
IUUC-Cho-024637	Choloepus hoffmanni	77.52	8.00e-84	302.00
IUUC-Cin-025180	Ciona intestinalis	51.80	7.00e-86	310.00
IUUC-Csv-026206	Ciona savignyi	47.12	8.00e-44	169.00
IUUC-Cgl-026696	Colletotrichum gloeosporioides	24.38	8.00e-13	67.80
IUUC-Dre-028092	Danio rerio	64.47	7.00e-118	416.00
IUUC-Dno-029501	Dasypus novemcinctus	87.87	6.00e-142	496.00
IUUC-Dor-030542	Dipodomys ordii	91.12	2.00e-164	571.00
IUUC-Dse-031188	Dothistroma septosporum	25.00	5.00e-15	75.10
IUUC-Dme-031734	Drosophila melanogaster	49.68	2.00e-79	288.00
IUUC-Eca-033577	Equus caballus	95.72	2.00e-171	594.00
IUUC-Fca-035761	Felis catus	95.39	1.00e-169	588.00
IUUC-Fox-037703	Fusarium oxysporum	26.65	5.00e-14	72.00
IUUC-Fso-038208	Fusarium solani	26.74	7.00e-14	71.20
IUUC-Gmo-038523	Gadus morhua	60.62	2.00e-62	231.00
IUUC-Ggr-040087	Gaeumannomyces graminis	41.03	7.00e-10	58.20
IUUC-Gac-042621	Gasterosteus aculeatus	61.01	6.00e-110	390.00
IUUC-Gma-042698	Glycine max	31.19	5.00e-33	134.00
IUUC-Ggo-045357	Gorilla gorilla	92.76	4.00e-167	580.00
IUUC-Hsa-046195	Homo sapiens	92.76	4.00e-167	580.00
IUUC-Hvu-047174	Hordeum vulgare	30.64	3.00e-36	145.00
IUUC-Itr-048487	Ictidomys tridecemlineatus	92.43	2.00e-159	554.00
IUUC-Lch-050569	Latimeria chalumnae	67.20	7.00e-115	406.00
IUUC-Lpe-050992	Leersia perrieri	34.95	2.00e-23	103.00
IUUC-Loc-052522	Lepisosteus oculatus	69.41	3.00e-116	411.00
IUUC-Lma-053254	Leptosphaeria maculans	24.50	4.00e-12	65.90
IUUC-Laf-053397	Loxodonta africana	95.39	8.00e-171	592.00
IUUC-Mcc-054681	Macaca mulatta	92.76	6.00e-167	580.00
IUUC-Meu-056723	Macropus eugenii	83.55	2.00e-151	527.00
IUUC-Mor-056961	Magnaporthe oryzae	24.37	3.00e-11	62.80
IUUC-Mpo-057359	Magnaporthe poae	24.32	8.00e-07	47.40
IUUC-Mtr-058063	Medicago truncatula	31.63	2.00e-34	139.00
IUUC-Mla-059004	Melampsora laricipopulina	30.03	2.00e-25	109.00
IUUC-Mvi-060460	Microbotryum violaceum	29.46	1.00e-25	110.00
IUUC-Mmr-060847	Microcebus murinus	95.39	1.00e-170	591.00
IUUC-Mdo-062480	Monodelphis domestica	84.87	1.00e-152	531.00
IUUC-Mmu-063809	Mus musculus	91.12	2.00e-161	561.00
IUUC-Mac-064870	Musa acuminata	31.19	5.00e-34	137.00
IUUC-Mpu-066322	Mustela putorius furo	95.72	3.00e-172	597.00
IUUC-Ncr-068898	Neurospora crassa	38.46	1.00e-07	50.80
IUUC-Nle-070049	Nomascus leucogenys	93.09	2.00e-167	581.00
IUUC-Opr-070972	Ochotona princeps	88.52	7.00e-158	549.00
IUUC-Ont-071682	Oreochromis niloticus	66.23	3.00e-118	417.00
IUUC-Oan-073296	Ornithorhynchus anatinus	98.31	1.00e-32	131.00
IUUC-Ocu-074218	Oryctolagus cuniculus	90.11	2.00e-131	461.00
IUUC-Oba-075284	Oryza barthii	31.86	4.00e-35	141.00
IUUC-Obr-076651	Oryza brachyantha	31.19	2.00e-36	145.00
IUUC-Ogl-077899	Oryza glaberrima	31.86	4.00e-35	141.00
IUUC-Ogu-078477	Oryza glumaepatula	32.54	7.00e-36	144.00
IUUC-Oin-080011	Oryza indica	31.86	5.00e-35	141.00
IUUC-Ome-081543	Oryza meridionalis	31.86	5.00e-35	141.00
IUUC-Oni-082955	Oryza nivara	31.86	5.00e-35	141.00
IUUC-Opu-083565	Oryza punctata	32.20	1.00e-35	143.00
IUUC-Oru-084474	Oryza rufipogon	31.86	5.00e-35	141.00
IUUC-Osa-085913	Oryza sativa	31.86	5.00e-35	141.00
IUUC-Ola-086851	Oryzias latipes	66.45	2.00e-119	421.00
IUUC-Olu-087724	Ostreococcus lucimarinus	33.01	2.00e-12	66.20
IUUC-Oga-087970	Otolemur garnettii	93.11	1.00e-165	575.00
IUUC-Oar-089756	Ovis aries	91.83	1.00e-157	548.00
IUUC-Ptr-091485	Pan troglodytes	91.78	2.00e-163	567.00
IUUC-Pan-091832	Papio anubis	93.09	2.00e-167	581.00
IUUC-Pma-094551	Petromyzon marinus	62.87	4.00e-109	387.00
IUUC-Ppa-095255	Physcomitrella patens	29.43	2.00e-32	132.00
IUUC-Pfo-096373	Poecilia formosa	66.01	7.00e-117	413.00
IUUC-Pab-098247	Pongo abelii	92.76	7.00e-167	579.00
IUUC-Pop-099186	Populus trichocarpa	30.85	7.00e-32	130.00
IUUC-Pca-100677	Procavia capensis	90.65	6.00e-140	489.00
IUUC-Ppe-101403	Prunus persica	29.59	1.00e-31	129.00
IUUC-Pva-103000	Pteropus vampyrus	94.74	1.00e-169	588.00
IUUC-Pgr-103663	Puccinia graminis	31.08	6.00e-32	131.00
IUUC-Ptt-103712	Puccinia triticina	40.00	6.00e-09	54.30
IUUC-Pte-104287	Pyrenophora teres	26.06	5.00e-17	82.00
IUUC-Pyt-104579	Pyrenophora triticirepentis	25.87	5.00e-14	72.00
IUUC-Rno-106069	Rattus norvegicus	91.12	2.00e-161	561.00
IUUC-Sha-106553	Sarcophilus harrisii	83.22	3.00e-152	530.00
IUUC-Smo-108874	Selaginella moellendorffii	32.57	7.00e-39	154.00
IUUC-Sit-110307	Setaria italica	31.74	5.00e-34	138.00
IUUC-Sly-111094	Solanum lycopersicum	32.66	6.00e-34	137.00
IUUC-Stu-112363	Solanum tuberosum	33.00	1.00e-33	136.00
IUUC-Sar-113480	Sorex araneus	92.11	3.00e-157	547.00
IUUC-Sbi-113939	Sorghum bicolor	31.74	1.00e-34	140.00
IUUC-Ssc-115644	Sus scrofa	96.38	1.00e-171	595.00
IUUC-Tru-118781	Takifugu rubripes	65.37	7.00e-119	419.00
IUUC-Tni-119672	Tetraodon nigroviridis	73.56	2.00e-34	136.00
IUUC-Tca-121795	Theobroma cacao	31.23	1.00e-35	143.00
IUUC-Tvi-122524	Trichoderma virens	27.34	1.00e-15	77.40
IUUC-Tae-122828	Triticum aestivum	30.98	2.00e-36	145.00
IUUC-Tme-127111	Tuber melanosporum	40.00	2.00e-09	57.00
IUUC-Ttr-128227	Tursiops truncatus	94.08	9.00e-167	578.00
IUUC-Vda-129924	Verticillium dahliae	27.50	8.00e-16	77.80
IUUC-Vpa-130802	Vicugna pacos	97.75	2.00e-45	176.00
IUUC-Vvi-131105	Vitis vinifera	32.42	5.00e-34	137.00
IUUC-Xtr-132830	Xenopus tropicalis	66.04	2.00e-123	434.00
IUUC-Xma-133618	Xiphophorus maculatus	65.79	4.00e-112	397.00
IUUC-Zma-135389	Zea mays	31.40	1.00e-33	136.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence