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Tag Content
UUCD2 ID IUUC-Sha-106553
UUCD1 version UUC-SaH-00216
Ensembl Protein ID ENSSHAP00000005366.1
UniProt Accession G3VQB1; G3VQB1_SARHA
Genbank Protein ID ENSSHAP00000005366
Protein Name Nitric oxide synthase-interacting protein
Genbank Nucleotide ID AEFK01124042
Gene Name NOSIP
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSHAG00000004689.1 ENSSHAT00000005419.1 ENSSHAP00000005366.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 7.30e-14 51.8 40 79
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk 41
           v ++ +C +sl++ +dPvv+p+G  y+r++I +++ ++++
   Q: 40   VKDFDCCCLSLQPCHDPVVTPDGFLYEREAILEYILHQKR 79
           567789*****************************88876 PP
   
Organism Sarcophilus harrisii
Functional Description
(View)

Functional Description


     Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
 Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
Protein Sequence
(Fasta)
MTRHGKNCTA GAVYTYHEKK KDTAASGYGT QNVRLSRDAV KDFDCCCLSL QPCHDPVVTP 60
DGFLYEREAI LEYILHQKRE IARQMKAYEK QRGAQQEERR ELSRAAAQDQ LRGFLEKEAA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sha-106553|E3,U-box|Sarcophilus harrisii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GATGACCCGT CACGGGAAGA ACTGCACCGC CGGCGCGGTA TACACATATC ACGAGAAGAA 60
AAAAGACACA GGTGATGGCA AAGGGGGCAG TTGGGGCACG GCCCTCCCCC TCGGGGTGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sha-106553|E3,U-box|Sarcophilus harrisii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
Interpro

IPR016818--Nitric_oxide_synth-interacting
IPR031790--Znf-NOSIP
IPR013083--Znf_RING/FYVE/PHD
Pfam

PF15906--zf-NOSIP
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003723--F:RNA binding
GO:0051001--P:negative regulation of nitric-oxide synthase activity
KEGG shr:100932263
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000769 Aegilops tauschii 45.35 4.00e-16 79.30
IUUC-Aml-002069 Ailuropoda melanoleuca 80.38 7.00e-148 516.00
IUUC-Atr-002661 Amborella trichopoda 33.45 4.00e-31 128.00
IUUC-Aca-004630 Anolis carolinensis 75.42 8.00e-134 469.00
IUUC-Aly-006316 Arabidopsis lyrata 30.90 1.00e-31 130.00
IUUC-Ath-007000 Arabidopsis thaliana 29.53 3.00e-31 128.00
IUUC-Acl-008175 Aspergillus clavatus 33.63 1.00e-06 47.80
IUUC-Afl-008440 Aspergillus flavus 34.21 2.00e-06 46.60
IUUC-Afu-009012 Aspergillus fumigatus 34.21 6.00e-07 48.50
IUUC-Ang-009556 Aspergillus niger 33.33 2.00e-06 46.60
IUUC-Aor-009892 Aspergillus oryzae 34.21 2.00e-06 46.60
IUUC-Ate-010473 Aspergillus terreus 31.30 6.00e-05 43.10
IUUC-Ame-011874 Astyanax mexicanus 63.96 2.00e-108 384.00
IUUC-Bgr-012090 Blumeria graminis 26.00 3.00e-05 42.40
IUUC-Bta-012956 Bos taurus 83.55 3.00e-151 526.00
IUUC-Bci-013897 Botrytis cinerea 41.25 2.00e-09 56.60
IUUC-Bdi-014968 Brachypodium distachyon 30.58 2.00e-34 139.00
IUUC-Bol-015578 Brassica oleracea 29.87 4.00e-35 141.00
IUUC-Bra-017234 Brassica rapa 29.87 4.00e-35 141.00
IUUC-Cel-018637 Caenorhabditis elegans 43.16 4.00e-58 218.00
IUUC-Cja-019632 Callithrix jacchus 82.84 6.00e-150 523.00
IUUC-Cfa-020192 Canis familiaris 82.84 3.00e-149 521.00
IUUC-Cpo-021939 Cavia porcellus 83.78 8.00e-147 512.00
IUUC-Cre-023005 Chlamydomonas reinhardtii 35.97 6.00e-46 177.00
IUUC-Csa-023802 Chlorocebus sabaeus 83.17 6.00e-150 523.00
IUUC-Cho-024637 Choloepus hoffmanni 66.36 9.00e-69 252.00
IUUC-Cin-025180 Ciona intestinalis 50.17 3.00e-83 301.00
IUUC-Csv-026206 Ciona savignyi 45.70 4.00e-43 167.00
IUUC-Cgl-026696 Colletotrichum gloeosporioides 27.18 2.00e-14 73.20
IUUC-Cne-026827 Cryptococcus neoformans 36.36 2.00e-06 46.20
IUUC-Dre-028092 Danio rerio 64.80 1.00e-114 405.00
IUUC-Dno-029501 Dasypus novemcinctus 79.28 2.00e-127 448.00
IUUC-Dor-030542 Dipodomys ordii 82.18 1.00e-149 521.00
IUUC-Dse-031188 Dothistroma septosporum 23.97 7.00e-13 67.80
IUUC-Dme-031734 Drosophila melanogaster 45.93 3.00e-78 285.00
IUUC-Eca-033577 Equus caballus 84.49 1.00e-151 528.00
IUUC-Fca-035761 Felis catus 84.16 3.00e-151 527.00
IUUC-Fox-037703 Fusarium oxysporum 28.40 1.00e-09 57.00
IUUC-Fso-038208 Fusarium solani 28.81 1.00e-10 60.10
IUUC-Gmo-038523 Gadus morhua 56.77 6.00e-60 223.00
IUUC-Ggr-040087 Gaeumannomyces graminis 39.74 1.00e-09 56.60
IUUC-Gac-042621 Gasterosteus aculeatus 59.43 2.00e-105 375.00
IUUC-Gma-042698 Glycine max 32.06 8.00e-33 133.00
IUUC-Ggo-045357 Gorilla gorilla 82.84 7.00e-150 522.00
IUUC-Hsa-046195 Homo sapiens 82.84 7.00e-150 522.00
IUUC-Hvu-047174 Hordeum vulgare 31.53 6.00e-36 144.00
IUUC-Itr-048487 Ictidomys tridecemlineatus 82.84 1.00e-146 512.00
IUUC-Lch-050569 Latimeria chalumnae 65.58 5.00e-111 393.00
IUUC-Lpe-050992 Leersia perrieri 35.86 5.00e-23 102.00
IUUC-Loc-052522 Lepisosteus oculatus 70.85 4.00e-118 417.00
IUUC-Lma-053254 Leptosphaeria maculans 34.09 2.00e-09 56.20
IUUC-Laf-053397 Loxodonta africana 84.49 4.00e-154 536.00
IUUC-Mcc-054681 Macaca mulatta 82.84 8.00e-150 523.00
IUUC-Meu-056723 Macropus eugenii 93.02 1.00e-163 568.00
IUUC-Mor-056961 Magnaporthe oryzae 39.29 8.00e-10 57.80
IUUC-Mpo-057359 Magnaporthe poae 26.20 1.00e-07 49.70
IUUC-Mtr-058063 Medicago truncatula 32.64 1.00e-34 140.00
IUUC-Mla-059004 Melampsora laricipopulina 30.06 2.00e-27 115.00
IUUC-Mvi-060460 Microbotryum violaceum 29.55 2.00e-24 106.00
IUUC-Mmr-060847 Microcebus murinus 83.17 2.00e-150 524.00
IUUC-Mdo-062480 Monodelphis domestica 93.36 3.00e-165 573.00
IUUC-Mmu-063809 Mus musculus 83.17 3.00e-149 520.00
IUUC-Mac-064870 Musa acuminata 31.71 1.00e-33 136.00
IUUC-Mpu-066322 Mustela putorius furo 84.16 1.00e-153 535.00
IUUC-Mlu-067556 Myotis lucifugus 81.25 2.00e-146 511.00
IUUC-Nfi-068440 Neosartorya fischeri 34.21 6.00e-07 48.50
IUUC-Ncr-068898 Neurospora crassa 37.18 2.00e-07 50.10
IUUC-Nle-070049 Nomascus leucogenys 82.84 7.00e-150 522.00
IUUC-Opr-070972 Ochotona princeps 80.07 6.00e-142 496.00
IUUC-Ont-071682 Oreochromis niloticus 65.23 4.00e-114 404.00
IUUC-Oan-073296 Ornithorhynchus anatinus 100.00 9.00e-33 132.00
IUUC-Ocu-074218 Oryctolagus cuniculus 82.62 4.00e-121 427.00
IUUC-Oba-075284 Oryza barthii 31.85 1.00e-34 139.00
IUUC-Obr-076651 Oryza brachyantha 31.60 2.00e-37 148.00
IUUC-Ogl-077899 Oryza glaberrima 31.85 1.00e-34 139.00
IUUC-Ogu-078477 Oryza glumaepatula 32.19 7.00e-35 140.00
IUUC-Oin-080011 Oryza indica 31.85 2.00e-34 139.00
IUUC-Olo-080545 Oryza longistaminata 31.52 8.00e-27 114.00
IUUC-Ome-081543 Oryza meridionalis 31.85 2.00e-34 139.00
IUUC-Oni-082955 Oryza nivara 31.85 2.00e-34 139.00
IUUC-Opu-083565 Oryza punctata 31.85 5.00e-34 137.00
IUUC-Oru-084474 Oryza rufipogon 31.85 2.00e-34 139.00
IUUC-Osa-085913 Oryza sativa 31.85 2.00e-34 139.00
IUUC-Ola-086851 Oryzias latipes 65.89 4.00e-117 414.00
IUUC-Olu-087724 Ostreococcus lucimarinus 36.89 4.00e-14 71.60
IUUC-Oga-087970 Otolemur garnettii 83.22 1.00e-148 518.00
IUUC-Oar-089756 Ovis aries 80.33 2.00e-140 491.00
IUUC-Ptr-091485 Pan troglodytes 81.85 2.00e-146 511.00
IUUC-Pan-091832 Papio anubis 82.84 6.00e-150 522.00
IUUC-Pma-094551 Petromyzon marinus 63.43 2.00e-108 384.00
IUUC-Pno-094830 Phaeosphaeria nodorum 34.95 3.00e-09 55.50
IUUC-Ppa-095255 Physcomitrella patens 31.06 2.00e-32 132.00
IUUC-Pfo-096373 Poecilia formosa 63.64 3.00e-115 407.00
IUUC-Pab-098247 Pongo abelii 82.84 9.00e-150 522.00
IUUC-Pop-099186 Populus trichocarpa 30.66 3.00e-31 128.00
IUUC-Pca-100677 Procavia capensis 79.42 6.00e-121 426.00
IUUC-Ppe-101403 Prunus persica 30.56 1.00e-32 132.00
IUUC-Pva-103000 Pteropus vampyrus 85.05 6.00e-153 533.00
IUUC-Pgr-103663 Puccinia graminis 30.96 1.00e-30 127.00
IUUC-Ptt-103712 Puccinia triticina 38.46 3.00e-08 52.40
IUUC-Pte-104287 Pyrenophora teres 27.46 2.00e-17 83.20
IUUC-Pyt-104579 Pyrenophora triticirepentis 26.69 4.00e-13 68.90
IUUC-Rno-106069 Rattus norvegicus 83.17 3.00e-149 520.00
IUUC-Smo-108874 Selaginella moellendorffii 34.01 2.00e-40 159.00
IUUC-Sit-110307 Setaria italica 31.86 1.00e-33 136.00
IUUC-Sly-111094 Solanum lycopersicum 32.87 1.00e-33 136.00
IUUC-Stu-112363 Solanum tuberosum 32.64 2.00e-33 135.00
IUUC-Sar-113480 Sorex araneus 82.39 1.00e-143 501.00
IUUC-Sbi-113939 Sorghum bicolor 32.19 4.00e-34 138.00
IUUC-Ssc-115644 Sus scrofa 84.82 2.00e-153 534.00
IUUC-Tru-118781 Takifugu rubripes 62.87 1.00e-115 409.00
IUUC-Tni-119672 Tetraodon nigroviridis 71.26 1.00e-33 133.00
IUUC-Tca-121795 Theobroma cacao 32.06 1.00e-36 146.00
IUUC-Tre-122037 Trichoderma reesei 26.44 1.00e-12 67.40
IUUC-Tvi-122524 Trichoderma virens 26.64 2.00e-17 83.20
IUUC-Tae-122828 Triticum aestivum 31.86 4.00e-36 144.00
IUUC-Tur-126387 Triticum urartu 31.13 1.00e-27 117.00
IUUC-Tme-127111 Tuber melanosporum 38.75 3.00e-09 55.80
IUUC-Ttr-128227 Tursiops truncatus 83.83 5.00e-151 526.00
IUUC-Vda-129924 Verticillium dahliae 26.36 2.00e-15 76.60
IUUC-Vpa-130802 Vicugna pacos 83.15 1.00e-39 155.00
IUUC-Vvi-131105 Vitis vinifera 32.40 8.00e-35 140.00
IUUC-Xtr-132830 Xenopus tropicalis 64.89 9.00e-121 426.00
IUUC-Xma-133618 Xiphophorus maculatus 63.73 5.00e-109 386.00
IUUC-Zma-135389 Zea mays 31.51 5.00e-32 130.00
Created Date 25-Jun-2017

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