iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000005761.3	ENSMMUT00000008090.3	ENSMMUP00000007607.3
ENSMMUG00000005761.3	ENSMMUT00000008089.3	ENSMMUP00000007606.3
ENSMMUG00000005761.3	ENSMMUT00000068299.1	ENSMMUP00000041430.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.10e-08	36.1	4	42
ULD/UDP/UFD/UBX	8.20e-20	72.2	210	291

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
             +le l+eMGF+r +a +aL+ + n  +eaA+++L+++
   Q: 4    LTALESLIEMGFPRGRAEKALALTgNQGIEAAMDWLMEH 42
           5689********************************987 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve....yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllv 79
           +++q+++q+RlpdG  l+++F+++++l +++ +ve    ++ +  +dp +L+s+fPrr +++ ++++ lqe+gLvps++l+v
   Q: 210  EYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVElhrgEEPGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIV 291
           578*****************************************************************************98 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAELTALESL IEMGFPRGRA EKALALTGNQ GIEAAMDWLM EHEDDPDVDE PLETPLGHVL 60
GREPTSSEQG GLEGSGSAAG EGKPILSEEE RQEQTKRMLE LVAQKQRERE EREEREALER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGC TGACGGCCCT TGAGAGTCTC ATCGAGATGG GCTTCCCCAG GGGACGCGCG 60
TAAGGGAGTT CCCCAACCCC GGCCTGCGGG GGTGGGGGGC CGCGGACCTG TCCTGGCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50030--UBA
PS50033--UBX

Pfam

PF00627--UBA
PF00789--UBX

SMART

SM00165--UBA
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0000502--C:proteasome complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1904293--P:negative regulation of ERAD pathway
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903094--P:negative regulation of protein K48-linked deubiquitination
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000157--P:negative regulation of ubiquitin-specific protease activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001103	Aegilops tauschii	42.11	3.00e-09	56.60
IUUC-Aml-002325	Ailuropoda melanoleuca	93.54	6.00e-115	406.00
IUUC-Aca-004329	Anolis carolinensis	71.43	3.00e-48	184.00
IUUC-Aly-005639	Arabidopsis lyrata	50.91	6.00e-12	65.10
IUUC-Ath-006887	Arabidopsis thaliana	41.67	5.00e-12	65.50
IUUC-Ago-007989	Ashbya gossypii	37.18	1.00e-06	47.40
IUUC-Ame-011399	Astyanax mexicanus	53.42	6.00e-61	227.00
IUUC-Bta-013151	Bos taurus	94.26	2.00e-118	418.00
IUUC-Bdi-014311	Brachypodium distachyon	54.55	1.00e-09	57.40
IUUC-Bol-016537	Brassica oleracea	50.91	1.00e-11	64.30
IUUC-Bra-017906	Brassica rapa	59.09	2.00e-11	63.90
IUUC-Cel-018300	Caenorhabditis elegans	34.85	4.00e-13	68.60
IUUC-Cja-019084	Callithrix jacchus	98.59	2.00e-106	378.00
IUUC-Cfa-020997	Canis familiaris	89.79	1.00e-91	329.00
IUUC-Cpo-021736	Cavia porcellus	77.78	2.00e-81	295.00
IUUC-Csa-024040	Chlorocebus sabaeus	99.66	4.00e-105	374.00
IUUC-Cho-024543	Choloepus hoffmanni	96.04	3.00e-65	241.00
IUUC-Cin-025719	Ciona intestinalis	39.12	4.00e-36	144.00
IUUC-Csv-025854	Ciona savignyi	37.33	6.00e-35	140.00
IUUC-Cme-027235	Cyanidioschyzon merolae	47.73	4.00e-08	52.80
IUUC-Dre-027745	Danio rerio	51.66	2.00e-58	219.00
IUUC-Dno-029598	Dasypus novemcinctus	93.60	7.00e-106	376.00
IUUC-Dor-030917	Dipodomys ordii	82.04	2.00e-90	325.00
IUUC-Dme-032055	Drosophila melanogaster	43.64	2.00e-23	103.00
IUUC-Ete-032960	Echinops telfairi	74.82	5.00e-72	264.00
IUUC-Eca-034294	Equus caballus	94.28	2.00e-108	385.00
IUUC-Eeu-034906	Erinaceus europaeus	90.88	4.00e-99	354.00
IUUC-Fca-035653	Felis catus	91.90	6.00e-98	350.00
IUUC-Gmo-038755	Gadus morhua	48.87	4.00e-53	201.00
IUUC-Gac-042481	Gasterosteus aculeatus	55.16	5.00e-58	217.00
IUUC-Ggo-044821	Gorilla gorilla	98.24	8.00e-98	350.00
IUUC-Hsa-046797	Homo sapiens	98.65	4.00e-106	377.00
IUUC-Itr-048850	Ictidomys tridecemlineatus	95.62	3.00e-116	411.00
IUUC-Lch-049508	Latimeria chalumnae	67.37	6.00e-33	134.00
IUUC-Laf-053932	Loxodonta africana	95.62	7.00e-126	443.00
IUUC-Mtr-058774	Medicago truncatula	50.00	9.00e-10	57.40
IUUC-Mvi-060245	Microbotryum violaceum	40.48	3.00e-12	65.90
IUUC-Mmr-060979	Microcebus murinus	94.61	4.00e-109	387.00
IUUC-Mdo-062299	Monodelphis domestica	86.27	1.00e-92	332.00
IUUC-Mmu-063212	Mus musculus	94.28	1.00e-111	395.00
IUUC-Mac-065072	Musa acuminata	60.53	1.00e-10	60.50
IUUC-Mpu-066540	Mustela putorius furo	94.28	2.00e-117	414.00
IUUC-Mlu-067589	Myotis lucifugus	91.25	9.00e-107	379.00
IUUC-Nle-069045	Nomascus leucogenys	97.23	1.00e-77	282.00
IUUC-Opr-070772	Ochotona princeps	86.91	2.00e-88	318.00
IUUC-Ont-072006	Oreochromis niloticus	54.46	4.00e-58	218.00
IUUC-Oan-073244	Ornithorhynchus anatinus	87.34	9.00e-36	143.00
IUUC-Ocu-074333	Oryctolagus cuniculus	95.62	2.00e-107	382.00
IUUC-Oba-075451	Oryza barthii	49.06	7.00e-11	61.60
IUUC-Obr-076923	Oryza brachyantha	55.10	2.00e-11	63.50
IUUC-Ogl-077259	Oryza glaberrima	37.84	5.00e-10	58.90
IUUC-Ogu-078589	Oryza glumaepatula	49.06	7.00e-11	61.60
IUUC-Ome-081253	Oryza meridionalis	49.06	6.00e-11	62.00
IUUC-Oni-082110	Oryza nivara	37.84	1.00e-10	60.50
IUUC-Opu-083336	Oryza punctata	49.06	8.00e-11	61.60
IUUC-Oru-085235	Oryza rufipogon	49.06	7.00e-11	61.60
IUUC-Osa-085611	Oryza sativa	49.06	7.00e-11	61.60
IUUC-Ola-086781	Oryzias latipes	55.02	1.00e-55	209.00
IUUC-Oga-088429	Otolemur garnettii	96.30	1.00e-106	379.00
IUUC-Oar-089885	Ovis aries	93.92	2.00e-118	418.00
IUUC-Ptr-091315	Pan troglodytes	97.89	1.00e-97	349.00
IUUC-Pan-092885	Papio anubis	99.66	4.00e-105	374.00
IUUC-Psi-093299	Pelodiscus sinensis	72.31	6.00e-63	233.00
IUUC-Pma-094221	Petromyzon marinus	64.37	2.00e-28	117.00
IUUC-Ppa-095484	Physcomitrella patens	51.11	2.00e-10	60.10
IUUC-Pfo-096188	Poecilia formosa	53.90	4.00e-55	207.00
IUUC-Pab-097881	Pongo abelii	91.92	4.00e-103	367.00
IUUC-Pop-098863	Populus trichocarpa	52.94	1.00e-11	64.70
IUUC-Pca-100977	Procavia capensis	94.33	8.00e-100	356.00
IUUC-Ppe-101243	Prunus persica	47.06	8.00e-10	57.80
IUUC-Pva-102169	Pteropus vampyrus	95.77	5.00e-101	360.00
IUUC-Rno-105459	Rattus norvegicus	92.93	9.00e-111	392.00
IUUC-Sha-107526	Sarcophilus harrisii	88.55	8.00e-92	330.00
IUUC-Ssl-108389	Sclerotinia sclerotiorum	25.93	1.00e-05	44.30
IUUC-Sit-110434	Setaria italica	36.59	3.00e-09	55.80
IUUC-Sar-112945	Sorex araneus	93.94	7.00e-66	243.00
IUUC-Sbi-114159	Sorghum bicolor	34.21	2.00e-10	59.70
IUUC-Ssc-116114	Sus scrofa	95.96	5.00e-104	370.00
IUUC-Tru-117839	Takifugu rubripes	52.60	2.00e-53	202.00
IUUC-Tsy-118813	Tarsius syrichta	73.24	8.00e-94	336.00
IUUC-Tni-120504	Tetraodon nigroviridis	54.28	2.00e-54	205.00
IUUC-Tbe-128034	Tupaia belangeri	95.77	1.00e-107	382.00
IUUC-Ttr-128468	Tursiops truncatus	88.85	3.00e-105	374.00
IUUC-Uma-129569	Ustilago maydis	34.62	2.00e-05	43.50
IUUC-Vpa-130179	Vicugna pacos	88.74	2.00e-71	261.00
IUUC-Xtr-132119	Xenopus tropicalis	63.42	1.00e-69	256.00
IUUC-Xma-134067	Xiphophorus maculatus	52.92	3.00e-55	208.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence