iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088429

Ensembl Protein ID

ENSOGAP00000010221.2

UniProt Accession

H0X4R9; H0X4R9_OTOGA

Genbank Protein ID

ENSOGAP00000010221

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03147751

Gene Name

UBXN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000011411.2	ENSOGAT00000011415.2	ENSOGAP00000010221.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.00e-08	35.0	4	42
ULD/UDP/UFD/UBX	3.80e-20	72.2	210	291

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
             +le l+eMGF+r +a +aL+ + n  +eaA+++L+++
   Q: 4    LTALESLIEMGFPRGRAEKALALTgNQGIEAAMDWLMEH 42
           5689********************************987 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve....yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllv 79
           +++q+++q+RlpdG  l+++F+++++l +++ +ve    ++ +  +dp +L+s+fPrr +++ ++++ lqe+gLvps++l+v
   Q: 210  EYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVElhrgEEPGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIV 291
           578*****************************************************************************98 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAELTALESL IEMGFPRGRA EKALALTGNQ GIEAAMDWLM EHEDDPDVDE PLDTPIGHIL 60
GREPTFSEQG GPEGPGSAAG EGKPILSEEK RQEQTKRMLE LVAQKQRERE EREAREALER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGT TGACGGCTCT GGAGAGTCTT ATAGAAATGG GCTTCCCCAG GGGACGCGCG 60
TAAGGGAGTC TCTCTAACCC CGGCCCGCGG GGGTGGGAGG CCACGAACCT GTCCTGGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50030--UBA
PS50033--UBX

Pfam

PF00627--UBA
PF00789--UBX

SMART

SM00165--UBA
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0000502--C:proteasome complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1904293--P:negative regulation of ERAD pathway
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903094--P:negative regulation of protein K48-linked deubiquitination
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000157--P:negative regulation of ubiquitin-specific protease activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001103	Aegilops tauschii	42.11	2.00e-09	56.60
IUUC-Aml-002325	Ailuropoda melanoleuca	94.56	1.00e-113	402.00
IUUC-Aca-004329	Anolis carolinensis	72.67	2.00e-50	191.00
IUUC-Aly-005639	Arabidopsis lyrata	50.91	1.00e-11	64.30
IUUC-Ath-006887	Arabidopsis thaliana	50.91	2.00e-11	63.50
IUUC-Ago-007989	Ashbya gossypii	37.18	6.00e-07	47.80
IUUC-Ame-011399	Astyanax mexicanus	53.75	6.00e-65	240.00
IUUC-Bta-013151	Bos taurus	93.58	2.00e-127	448.00
IUUC-Bdi-014311	Brachypodium distachyon	54.55	1.00e-09	57.80
IUUC-Bol-016537	Brassica oleracea	50.91	2.00e-11	63.50
IUUC-Bra-017906	Brassica rapa	59.09	2.00e-11	63.90
IUUC-Cel-018300	Caenorhabditis elegans	34.85	4.00e-13	68.60
IUUC-Cja-019084	Callithrix jacchus	96.13	9.00e-105	372.00
IUUC-Cfa-020997	Canis familiaris	91.55	1.00e-90	326.00
IUUC-Cpo-021736	Cavia porcellus	80.81	6.00e-84	303.00
IUUC-Csa-024040	Chlorocebus sabaeus	96.63	9.00e-104	369.00
IUUC-Cho-024543	Choloepus hoffmanni	95.05	4.00e-73	267.00
IUUC-Cin-025719	Ciona intestinalis	39.66	5.00e-41	160.00
IUUC-Csv-025854	Ciona savignyi	38.67	5.00e-40	157.00
IUUC-Cme-027235	Cyanidioschyzon merolae	47.73	4.00e-08	52.80
IUUC-Dre-027745	Danio rerio	52.51	2.00e-60	225.00
IUUC-Dno-029598	Dasypus novemcinctus	92.59	3.00e-104	371.00
IUUC-Dor-030917	Dipodomys ordii	81.69	5.00e-91	327.00
IUUC-Dme-032055	Drosophila melanogaster	42.77	5.00e-25	108.00
IUUC-Ete-032960	Echinops telfairi	76.60	9.00e-79	286.00
IUUC-Eca-034294	Equus caballus	95.62	4.00e-115	407.00
IUUC-Eeu-034906	Erinaceus europaeus	90.18	9.00e-107	379.00
IUUC-Fca-035653	Felis catus	92.96	2.00e-96	345.00
IUUC-Gmo-038755	Gadus morhua	50.96	1.00e-57	216.00
IUUC-Gac-042481	Gasterosteus aculeatus	53.23	2.00e-57	216.00
IUUC-Gma-042684	Glycine max	48.15	1.00e-10	60.80
IUUC-Ggo-044821	Gorilla gorilla	95.07	9.00e-97	346.00
IUUC-Hsa-046797	Homo sapiens	95.62	5.00e-105	373.00
IUUC-Itr-048850	Ictidomys tridecemlineatus	94.61	4.00e-116	410.00
IUUC-Lch-049508	Latimeria chalumnae	51.84	3.00e-56	211.00
IUUC-Laf-053932	Loxodonta africana	94.61	2.00e-133	468.00
IUUC-Mcc-055300	Macaca mulatta	96.30	1.00e-103	369.00
IUUC-Mtr-058774	Medicago truncatula	50.00	7.00e-10	57.80
IUUC-Mvi-060245	Microbotryum violaceum	40.48	8.00e-12	64.30
IUUC-Mmr-060979	Microcebus murinus	94.95	2.00e-112	398.00
IUUC-Mdo-062299	Monodelphis domestica	85.56	7.00e-97	346.00
IUUC-Mmu-063212	Mus musculus	92.59	7.00e-118	416.00
IUUC-Mac-065377	Musa acuminata	53.33	1.00e-11	60.80
IUUC-Mpu-066540	Mustela putorius furo	95.29	1.00e-115	409.00
IUUC-Mlu-067589	Myotis lucifugus	93.94	5.00e-109	387.00
IUUC-Nle-069045	Nomascus leucogenys	94.47	3.00e-78	284.00
IUUC-Opr-070772	Ochotona princeps	89.40	1.00e-90	326.00
IUUC-Ont-072006	Oreochromis niloticus	54.14	2.00e-57	215.00
IUUC-Oan-073244	Ornithorhynchus anatinus	61.05	7.00e-48	183.00
IUUC-Ocu-074333	Oryctolagus cuniculus	93.94	2.00e-105	375.00
IUUC-Oba-075451	Oryza barthii	46.77	4.00e-11	62.40
IUUC-Obr-076923	Oryza brachyantha	55.10	2.00e-11	63.20
IUUC-Ogl-077259	Oryza glaberrima	29.53	6.00e-10	58.50
IUUC-Ogu-078589	Oryza glumaepatula	46.77	4.00e-11	62.40
IUUC-Oin-079151	Oryza indica	46.77	3.00e-11	62.80
IUUC-Ome-081253	Oryza meridionalis	46.77	4.00e-11	62.80
IUUC-Oni-082110	Oryza nivara	39.77	1.00e-10	60.50
IUUC-Opu-083336	Oryza punctata	46.77	4.00e-11	62.40
IUUC-Oru-085235	Oryza rufipogon	46.77	4.00e-11	62.80
IUUC-Osa-085611	Oryza sativa	46.77	4.00e-11	62.80
IUUC-Ola-086781	Oryzias latipes	53.38	1.00e-54	206.00
IUUC-Oar-089885	Ovis aries	93.24	2.00e-127	447.00
IUUC-Ptr-091315	Pan troglodytes	95.05	1.00e-96	346.00
IUUC-Pan-092885	Papio anubis	96.63	9.00e-104	369.00
IUUC-Psi-093299	Pelodiscus sinensis	70.78	2.00e-65	241.00
IUUC-Pma-094221	Petromyzon marinus	64.37	2.00e-28	117.00
IUUC-Ppa-095484	Physcomitrella patens	51.11	2.00e-10	60.10
IUUC-Pfo-096188	Poecilia formosa	53.59	2.00e-54	205.00
IUUC-Pab-097881	Pongo abelii	90.24	8.00e-102	363.00
IUUC-Pop-098863	Populus trichocarpa	52.94	7.00e-12	65.10
IUUC-Pca-100977	Procavia capensis	91.99	6.00e-108	383.00
IUUC-Ppe-101243	Prunus persica	47.06	3.00e-10	58.90
IUUC-Pva-102169	Pteropus vampyrus	94.72	2.00e-99	355.00
IUUC-Rno-105459	Rattus norvegicus	91.92	2.00e-117	414.00
IUUC-Sha-107526	Sarcophilus harrisii	87.21	2.00e-97	348.00
IUUC-Ssl-108389	Sclerotinia sclerotiorum	27.34	3.00e-06	46.60
IUUC-Sit-110434	Setaria italica	30.43	1.00e-09	57.00
IUUC-Sar-112945	Sorex araneus	93.07	1.00e-71	262.00
IUUC-Sbi-114159	Sorghum bicolor	30.81	2.00e-10	59.70
IUUC-Ssc-116114	Sus scrofa	94.61	2.00e-102	365.00
IUUC-Tru-117839	Takifugu rubripes	53.21	3.00e-57	214.00
IUUC-Tsy-118813	Tarsius syrichta	73.24	5.00e-100	357.00
IUUC-Tni-120504	Tetraodon nigroviridis	55.70	5.00e-57	214.00
IUUC-Tae-124350	Triticum aestivum	42.11	2.00e-09	56.60
IUUC-Tur-126615	Triticum urartu	42.11	2.00e-09	56.60
IUUC-Tbe-128034	Tupaia belangeri	93.66	3.00e-106	377.00
IUUC-Ttr-128468	Tursiops truncatus	88.18	1.00e-105	375.00
IUUC-Uma-129569	Ustilago maydis	34.62	1.00e-05	43.90
IUUC-Vpa-130179	Vicugna pacos	88.74	1.00e-79	289.00
IUUC-Vvi-131064	Vitis vinifera	48.15	1.00e-10	60.80
IUUC-Xtr-132119	Xenopus tropicalis	62.75	4.00e-69	254.00
IUUC-Xma-134067	Xiphophorus maculatus	52.60	7.00e-55	207.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence