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Tag Content
UUCD2 ID IUUC-Aml-001397
UUCD1 version UUC-AiM-00625
Ensembl Protein ID ENSAMEP00000011713.1
UniProt Accession G1LXB0; G1LXB0_AILME
Genbank Protein ID ENSAMEP00000011713
Protein Name Uncharacterized protein
Genbank Nucleotide ID ACTA01058579
Gene Name FBXW11
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000011107.1 ENSAMET00000012206.1 ENSAMEP00000011709.1
ENSAMEG00000011107.1 ENSAMET00000012210.1 ENSAMEP00000011713.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.40e-57 189.1 441 475
UBD/Beta-Prp 7.10e-69 232.3 354 519
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ v+c++f d +++vsG++Dg+ikvWDl    +
   Q: 441  GHEELVRCIRF-DnKRIVSGAYDGKIKVWDLQAALD 475
           8**********.44****************977665 PP
   

   UBD/Beta-Prp
   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
           +l r l gh a+v+ v+f+++  ++v++s Drtikvw+ st++ v+tl+gh++ + +l++      +vsGs+d+tir+wd+e g cl+ 
   Q: 354  TLRRVLVGHRAAVNVVDFDDK--YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLR- 437
           4556679*************9..8**************************************..************************. PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           +l+gh+++v+c++++   + +vsG++D+++++Wdl         ++  +lrtl + h ++v  l+fd+  ++++s s+d t+ +wd+
   Q: 438  VLEGHEELVRCIRFDN--KRIVSGAYDGKIKVWDLqaaldprapASTLCLRTLVE-HSGRVFRLQFDE--FQIISSSHDDTILIWDF 519
           ***************9..***********************************99.************..99**************7 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
MEPDSVIEDK TIELMCSVPR SLWLGCANLV ESMCALSCLQ SMPSVRCLQI SNGTSSVIVS 60
RKRPSEGNYQ KEKDLCIKYF DQWSESDQVE FVEHLISRMC HYQHGHINSY LKPMLQRDFI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-001397|E3,WD_repeat;UBD,Beta-Prp|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGAGCCCG ACTCGGTGAT TGAGGACAAG ACCATCGAGC TCATGGTGAG TGCGGCCCGC 60
TGGACCGTTC TTCCGTCCGG CCCCGGGCGG GCCTGCCCAC CCCAACGTCC GGCGCGAGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-001397|E3,WD_repeat;UBD,Beta-Prp|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR021977--Beta-TrCP_D
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12125--Beta-TrCP_D
PF12937--F-box-like
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM01028--Beta-TrCP_D
SM00256--FBOX
SM00320--WD40
Gene Ontology

GO:0005813--C:centrosome
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0042347--P:negative regulation of NF-kappaB import into nucleus
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0042753--P:positive regulation of circadian rhythm
GO:0045862--P:positive regulation of proteolysis
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006470--P:protein dephosphorylation
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003449 Anas platyrhynchos 94.76 0.00e+00 1068.00
IUUC-Ang-009766 Aspergillus niger 31.41 5.00e-52 199.00
IUUC-Ame-011174 Astyanax mexicanus 83.92 0.00e+00 983.00
IUUC-Bta-012920 Bos taurus 100.00 0.00e+00 1023.00
IUUC-Cja-018879 Callithrix jacchus 100.00 0.00e+00 1120.00
IUUC-Cfa-020021 Canis familiaris 100.00 0.00e+00 1120.00
IUUC-Cpo-022151 Cavia porcellus 99.60 0.00e+00 1014.00
IUUC-Csa-024095 Chlorocebus sabaeus 100.00 0.00e+00 1021.00
IUUC-Cho-024658 Choloepus hoffmanni 99.62 9.00e-156 543.00
IUUC-Dre-028160 Danio rerio 92.34 0.00e+00 953.00
IUUC-Dno-029485 Dasypus novemcinctus 88.96 0.00e+00 890.00
IUUC-Dor-030498 Dipodomys ordii 99.43 0.00e+00 1082.00
IUUC-Dse-031287 Dothistroma septosporum 29.14 2.00e-52 201.00
IUUC-Eca-033804 Equus caballus 100.00 0.00e+00 1036.00
IUUC-Fca-035887 Felis catus 94.29 0.00e+00 1038.00
IUUC-Fal-036783 Ficedula albicollis 95.48 0.00e+00 1038.00
IUUC-Gmo-038590 Gadus morhua 88.03 0.00e+00 974.00
IUUC-Gga-040628 Gallus gallus 95.10 0.00e+00 1033.00
IUUC-Gac-041305 Gasterosteus aculeatus 88.58 0.00e+00 992.00
IUUC-Ggo-044604 Gorilla gorilla 100.00 0.00e+00 1120.00
IUUC-Hsa-046139 Homo sapiens 100.00 0.00e+00 1120.00
IUUC-Lch-050460 Latimeria chalumnae 97.17 0.00e+00 996.00
IUUC-Laf-053968 Loxodonta africana 96.27 0.00e+00 1108.00
IUUC-Mcc-055822 Macaca mulatta 91.58 0.00e+00 1063.00
IUUC-Mga-059225 Meleagris gallopavo 98.99 0.00e+00 1008.00
IUUC-Mvi-060284 Microbotryum violaceum 44.95 2.00e-69 257.00
IUUC-Mmr-060746 Microcebus murinus 100.00 0.00e+00 1120.00
IUUC-Mdo-062005 Monodelphis domestica 99.39 0.00e+00 1016.00
IUUC-Mmu-063851 Mus musculus 95.91 0.00e+00 1105.00
IUUC-Mpu-065716 Mustela putorius furo 100.00 0.00e+00 1022.00
IUUC-Mlu-067001 Myotis lucifugus 100.00 0.00e+00 1021.00
IUUC-Nle-069788 Nomascus leucogenys 93.73 0.00e+00 1033.00
IUUC-Opr-071229 Ochotona princeps 99.82 0.00e+00 1118.00
IUUC-Ont-071792 Oreochromis niloticus 89.57 0.00e+00 998.00
IUUC-Oan-072782 Ornithorhynchus anatinus 95.48 0.00e+00 1038.00
IUUC-Ocu-074894 Oryctolagus cuniculus 96.27 0.00e+00 1108.00
IUUC-Ola-086985 Oryzias latipes 85.87 0.00e+00 998.00
IUUC-Oga-088604 Otolemur garnettii 99.80 0.00e+00 1020.00
IUUC-Oar-090412 Ovis aries 96.05 0.00e+00 1043.00
IUUC-Ptr-091039 Pan troglodytes 99.82 0.00e+00 1118.00
IUUC-Pan-092770 Papio anubis 96.12 0.00e+00 1060.00
IUUC-Psi-093887 Pelodiscus sinensis 94.19 0.00e+00 1063.00
IUUC-Pno-094808 Phaeosphaeria nodorum 29.50 2.00e-45 177.00
IUUC-Pfo-096783 Poecilia formosa 86.22 0.00e+00 1002.00
IUUC-Pva-102547 Pteropus vampyrus 99.81 0.00e+00 1105.00
IUUC-Rno-105246 Rattus norvegicus 95.67 0.00e+00 1041.00
IUUC-Sha-107339 Sarcophilus harrisii 99.39 0.00e+00 1016.00
IUUC-Sja-107743 Schizosaccharomyces japonicus 35.38 5.00e-74 271.00
IUUC-Spo-108200 Schizosaccharomyces pombe 31.92 2.00e-66 246.00
IUUC-Tgu-116541 Taeniopygia guttata 94.75 0.00e+00 1069.00
IUUC-Tru-117671 Takifugu rubripes 85.16 0.00e+00 989.00
IUUC-Tni-120359 Tetraodon nigroviridis 85.79 0.00e+00 939.00
IUUC-Tbe-127418 Tupaia belangeri 93.74 0.00e+00 1005.00
IUUC-Ttr-129131 Tursiops truncatus 100.00 0.00e+00 1119.00
IUUC-Vpa-130668 Vicugna pacos 99.63 0.00e+00 1107.00
IUUC-Xma-133187 Xiphophorus maculatus 95.36 1.00e-157 548.00
Created Date 25-Jun-2017

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