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Tag Content
iUUCD ID IUUC-Psi-093344
Ensembl Protein ID ENSPSIP00000009498.1
UniProt Accession K7FN88; K7FN88_PELSI
Genbank Protein ID ENSPSIP00000009498
Protein Name Phosphoinositide phospholipase C
Genbank Nucleotide ID AGCU01077768
Gene Name PLCG1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPSIG00000008328.1 ENSPSIT00000009545.1 ENSPSIP00000009498.1
ENSPSIG00000008328.1 ENSPSIT00000009552.1 ENSPSIP00000009505.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 7.20e-12 45.1 790 847
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGl.fPenFvekl 62
           +k  v++l+dy+aq +deLt+ k  +++ +  e+q++gW++g  +  gk+ l fP+n+ve+l
   Q: 790  FKCAVKALFDYKAQREDELTFMKNAIIQNV--EKQEGGWWRG--DYGGKKQLwFPSNYVEEL 847
           56789************************9..9*********..676666655*******98 PP
   
Organism Pelodiscus sinensis
Protein Sequence
(Fasta)
AEGVMASAFS NGPGVPSEAE VVHLCRSLEV GTVMTLFYSK KSQRPERKTF QVKLETRQIT 60
WSRGSEKVEG AIDIREIQEI RPGNNSRDFD RYQEDPSFRP DPSHCFVVLY GMEFRLKTLS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Psi-093344|UBD,SH3|Pelodiscus sinensis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAAGGGACGA GCCCTCCCCC GCGGCGCCAT GCACTGAAGC AGCGGCTGGG ATTGTTTGCG 60
CGCTGAGTCC CACCAGCGGG GAGCGTGGAG GGCGGCAGTT CCCTTTTGTT TGGAGATTTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Psi-093344|UBD,SH3|Pelodiscus sinensis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0807--Transducer
Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR016279--PLC-gamma
IPR028380--PLC-gamma1
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain
PROSITE

PS50004--C2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50003--PH_DOMAIN
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3
Pfam

PF00168--C2
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
SMART

SM00239--C2
SM00233--PH
SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3
Gene Ontology

GO:0005911--C:cell-cell junction
GO:0008180--C:COP9 signalosome
GO:0005829--C:cytosol
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0005509--F:calcium ion binding
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0019722--P:calcium-mediated signaling
GO:0016477--P:cell migration
GO:0071364--P:cellular response to epidermal growth factor stimulus
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0009395--P:phospholipid catabolic process
GO:0045766--P:positive regulation of angiogenesis
GO:0043536--P:positive regulation of blood vessel endothelial cell migration
GO:0051281--P:positive regulation of release of sequestered calcium ion into cytosol
GO:0050852--P:T cell receptor signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001452 Ailuropoda melanoleuca 86.45 0.00e+00 2274.00
IUUC-Apl-003541 Anas platyrhynchos 69.43 0.00e+00 1724.00
IUUC-Aca-005291 Anolis carolinensis 87.18 0.00e+00 2264.00
IUUC-Ame-011004 Astyanax mexicanus 68.61 0.00e+00 1767.00
IUUC-Bta-012660 Bos taurus 86.30 0.00e+00 2167.00
IUUC-Cja-019206 Callithrix jacchus 86.09 0.00e+00 2264.00
IUUC-Cfa-020257 Canis familiaris 86.38 0.00e+00 2166.00
IUUC-Cpo-022391 Cavia porcellus 81.22 0.00e+00 2120.00
IUUC-Csa-024170 Chlorocebus sabaeus 88.00 0.00e+00 1694.00
IUUC-Cin-025520 Ciona intestinalis 47.21 0.00e+00 1095.00
IUUC-Dre-027944 Danio rerio 71.94 0.00e+00 1840.00
IUUC-Dno-029440 Dasypus novemcinctus 85.51 0.00e+00 2072.00
IUUC-Dor-031001 Dipodomys ordii 85.62 0.00e+00 2263.00
IUUC-Eca-033809 Equus caballus 86.46 0.00e+00 2174.00
IUUC-Fca-036510 Felis catus 86.22 0.00e+00 2164.00
IUUC-Fal-037541 Ficedula albicollis 90.08 0.00e+00 2135.00
IUUC-Gmo-038630 Gadus morhua 65.88 0.00e+00 1422.00
IUUC-Gga-040142 Gallus gallus 90.21 0.00e+00 2322.00
IUUC-Ggo-045063 Gorilla gorilla 86.55 0.00e+00 2284.00
IUUC-Hsa-046428 Homo sapiens 86.55 0.00e+00 2284.00
IUUC-Itr-048245 Ictidomys tridecemlineatus 86.31 0.00e+00 2244.00
IUUC-Lch-049766 Latimeria chalumnae 79.74 0.00e+00 1937.00
IUUC-Loc-052285 Lepisosteus oculatus 77.32 0.00e+00 2001.00
IUUC-Laf-053365 Loxodonta africana 85.49 0.00e+00 2147.00
IUUC-Mcc-054871 Macaca mulatta 86.38 0.00e+00 2274.00
IUUC-Meu-056724 Macropus eugenii 82.62 0.00e+00 2012.00
IUUC-Mga-059329 Meleagris gallopavo 88.89 0.00e+00 2193.00
IUUC-Mmr-061110 Microcebus murinus 86.08 0.00e+00 2265.00
IUUC-Mdo-062448 Monodelphis domestica 86.61 0.00e+00 2299.00
IUUC-Mmu-063565 Mus musculus 86.51 0.00e+00 2281.00
IUUC-Mpu-066683 Mustela putorius furo 86.63 0.00e+00 2283.00
IUUC-Mlu-067779 Myotis lucifugus 85.96 0.00e+00 2161.00
IUUC-Nle-069219 Nomascus leucogenys 87.12 0.00e+00 1916.00
IUUC-Opr-070766 Ochotona princeps 82.89 0.00e+00 1286.00
IUUC-Ont-072524 Oreochromis niloticus 73.90 0.00e+00 1936.00
IUUC-Oan-073214 Ornithorhynchus anatinus 86.96 9.00e-43 165.00
IUUC-Ocu-074361 Oryctolagus cuniculus 85.00 0.00e+00 2224.00
IUUC-Ola-086820 Oryzias latipes 72.76 0.00e+00 1932.00
IUUC-Oga-088172 Otolemur garnettii 86.62 0.00e+00 2289.00
IUUC-Oar-090306 Ovis aries 83.69 0.00e+00 2093.00
IUUC-Ptr-090682 Pan troglodytes 86.47 0.00e+00 2282.00
IUUC-Pan-092835 Papio anubis 86.70 0.00e+00 1623.00
IUUC-Pfo-096984 Poecilia formosa 72.32 0.00e+00 1892.00
IUUC-Pab-097871 Pongo abelii 86.48 0.00e+00 2243.00
IUUC-Pop-099175 Populus trichocarpa 25.00 7.50e-02 31.20
IUUC-Pca-100772 Procavia capensis 79.91 0.00e+00 2067.00
IUUC-Pva-102790 Pteropus vampyrus 86.71 0.00e+00 2237.00
IUUC-Rno-105974 Rattus norvegicus 86.54 0.00e+00 2290.00
IUUC-Sar-112995 Sorex araneus 84.89 0.00e+00 2206.00
IUUC-Ssc-115360 Sus scrofa 86.46 0.00e+00 2283.00
IUUC-Tgu-116585 Taeniopygia guttata 87.88 0.00e+00 2232.00
IUUC-Tru-117742 Takifugu rubripes 73.81 0.00e+00 1961.00
IUUC-Tsy-119259 Tarsius syrichta 86.43 0.00e+00 759.00
IUUC-Tni-120833 Tetraodon nigroviridis 66.69 0.00e+00 1674.00
IUUC-Tbe-127504 Tupaia belangeri 73.29 0.00e+00 1229.00
IUUC-Ttr-128650 Tursiops truncatus 87.16 0.00e+00 1175.00
IUUC-Xtr-132862 Xenopus tropicalis 77.42 0.00e+00 1974.00
Created Date 25-Jun-2017

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