iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000015489.3	ENSMMUT00000021724.3	ENSMMUP00000020321.3
ENSMMUG00000015489.3	ENSMMUT00000041925.2	ENSMMUP00000034935.2
ENSMMUG00000015489.3	ENSMMUT00000041928.2	ENSMMUP00000034938.2
ENSMMUG00000015489.3	ENSMMUT00000021726.3	ENSMMUP00000020323.3
ENSMMUG00000015489.3	ENSMMUT00000076376.1	ENSMMUP00000054367.1
ENSMMUG00000015489.3	ENSMMUT00000021728.3	ENSMMUP00000020325.3
ENSMMUG00000015489.3	ENSMMUT00000021730.3	ENSMMUP00000020327.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.80e-13	50.3	1634	1685

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvk..elegkrGlfP 55
             v++d++a n++eLt+++G +v+v+e  +   +W+           +Gl+P
   Q: 1634 TVVIHDFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTtdRSPAAEGLVP 1685
           679********************************97755334445678887 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

LVMTCGRGCG NGRKHANFIF SFCVSGFRKN DEMKAMDVLP ILKEKVAYLS GGRDKRGGPI 60
LTFPARSNHD RIRQEDLRRL ISYLACIPSE EVCKRGFTVI VDMRGSKWDS IKPLLKILQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCACAGA AGCCGTGTAT TTTTAATTTT TTAGAACGTT TTTATAGTCC CACACTGTTT 60
TCCTAAACAG CTCTTCAGGG CATGGAACAC AGCCTGCCTT TTTGATCTGA GGAACTTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR001251--CRAL-TRIO_dom
IPR000219--DH-domain
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR013098--Ig_I-set
IPR003599--Ig_sub
IPR003598--Ig_sub2
IPR011009--Kinase-like_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain
IPR018159--Spectrin/alpha-actinin
IPR002017--Spectrin_repeat
IPR028570--TRIO

PROSITE

PS50191--CRAL_TRIO
PS50010--DH_2
PS50835--IG_LIKE
PS50003--PH_DOMAIN
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF00650--CRAL_TRIO
PF07679--I-set
PF00169--PH
PF00069--Pkinase
PF00621--RhoGEF
PF00018--SH3_1
PF00435--Spectrin

SMART

SM00409--IG
SM00408--IGc2
SM00233--PH
SM00325--RhoGEF
SM00220--S_TKc
SM00516--SEC14
SM00326--SH3
SM00150--SPEC

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001797	Ailuropoda melanoleuca	94.92	0.00e+00	5625.00
IUUC-Apl-003498	Anas platyrhynchos	93.53	0.00e+00	5199.00
IUUC-Bta-013121	Bos taurus	94.37	0.00e+00	5523.00
IUUC-Cja-018919	Callithrix jacchus	98.89	0.00e+00	4419.00
IUUC-Cfa-020547	Canis familiaris	95.13	0.00e+00	5556.00
IUUC-Cpo-022301	Cavia porcellus	96.21	0.00e+00	5673.00
IUUC-Csa-023889	Chlorocebus sabaeus	99.54	0.00e+00	5733.00
IUUC-Dre-028386	Danio rerio	88.56	0.00e+00	3912.00
IUUC-Dno-028888	Dasypus novemcinctus	94.83	0.00e+00	5574.00
IUUC-Dor-030992	Dipodomys ordii	91.98	0.00e+00	4009.00
IUUC-Ete-033167	Echinops telfairi	91.21	0.00e+00	1701.00
IUUC-Eca-033685	Equus caballus	98.39	0.00e+00	4351.00
IUUC-Fca-035647	Felis catus	97.77	0.00e+00	4373.00
IUUC-Fal-036845	Ficedula albicollis	97.48	0.00e+00	4365.00
IUUC-Gga-040959	Gallus gallus	93.57	0.00e+00	5602.00
IUUC-Gac-041349	Gasterosteus aculeatus	87.25	0.00e+00	3786.00
IUUC-Ggo-045170	Gorilla gorilla	99.60	0.00e+00	4395.00
IUUC-Hsa-046059	Homo sapiens	99.38	0.00e+00	4424.00
IUUC-Lch-050010	Latimeria chalumnae	92.54	0.00e+00	4078.00
IUUC-Loc-052783	Lepisosteus oculatus	86.48	0.00e+00	5079.00
IUUC-Laf-053884	Loxodonta africana	98.66	0.00e+00	4377.00
IUUC-Mga-060008	Meleagris gallopavo	92.33	0.00e+00	5534.00
IUUC-Mmr-061081	Microcebus murinus	96.50	0.00e+00	5684.00
IUUC-Mdo-062888	Monodelphis domestica	98.32	0.00e+00	4023.00
IUUC-Mmu-063327	Mus musculus	95.63	0.00e+00	5584.00
IUUC-Mpu-066905	Mustela putorius furo	95.28	0.00e+00	5566.00
IUUC-Mlu-068215	Myotis lucifugus	95.52	0.00e+00	4304.00
IUUC-Nle-069414	Nomascus leucogenys	97.38	0.00e+00	5556.00
IUUC-Opr-070819	Ochotona princeps	94.43	0.00e+00	4229.00
IUUC-Ont-072678	Oreochromis niloticus	88.85	0.00e+00	3890.00
IUUC-Oan-072974	Ornithorhynchus anatinus	98.04	0.00e+00	4380.00
IUUC-Ocu-074919	Oryctolagus cuniculus	96.03	0.00e+00	5595.00
IUUC-Oga-088068	Otolemur garnettii	96.41	0.00e+00	5710.00
IUUC-Oar-090050	Ovis aries	95.13	0.00e+00	4254.00
IUUC-Ptr-090841	Pan troglodytes	98.00	0.00e+00	5594.00
IUUC-Psi-093088	Pelodiscus sinensis	92.64	0.00e+00	5573.00
IUUC-Pfo-097201	Poecilia formosa	77.74	0.00e+00	3421.00
IUUC-Pab-098130	Pongo abelii	98.06	0.00e+00	5595.00
IUUC-Pca-100839	Procavia capensis	91.34	0.00e+00	3848.00
IUUC-Pva-102115	Pteropus vampyrus	94.63	0.00e+00	2897.00
IUUC-Rno-105207	Rattus norvegicus	95.39	0.00e+00	5565.00
IUUC-Sha-107011	Sarcophilus harrisii	89.84	0.00e+00	4285.00
IUUC-Tgu-116970	Taeniopygia guttata	93.20	0.00e+00	5503.00
IUUC-Tru-117758	Takifugu rubripes	87.44	0.00e+00	3846.00
IUUC-Ttr-128857	Tursiops truncatus	90.27	0.00e+00	3982.00
IUUC-Xtr-131909	Xenopus tropicalis	86.88	0.00e+00	5190.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence