iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033667

Ensembl Protein ID

ENSECAP00000016844.1

UniProt Accession

F7BRQ1; F7BRQ1_HORSE

Protein Name

Uncharacterized protein

Gene Name

UBQLN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000019110.1	ENSECAT00000020517.1	ENSECAP00000016844.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	4.90e-10	39.4	545	582
ULD/UDP/UBQ/UBQ_PIM	3.00e-23	81.7	36	108

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 545  FQQQLEQLSAMGFlNREANLQALIATGGDINAAIERLL 582
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           mk+tvkt+k++   + v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tLs++gi+dg +vhlv+k+++
   Q: 36   MKVTVKTPKKED--FAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQN 108
           99*****98888..99********************************************************987 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAENSESGGP PSSQDSAAAA EGAGATAAAS AEPKIMKVTV KTPKKEDFAV PENSSVQQFK 60
EEISKRFKSH TDQLVLIFAG KILKDQDTLS QHGIHDGLTV HLVIKTQNRP QDHSAQQTNT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGAGA ATAGTGAAAG CGGCGGCCCT CCGAGCTCCC AGGACAGCGC CGCCGCGGCC 60
GAAGGTGCCG GCGCCACCGC GGCCCGCTGC CTCCGCGGAG CCAAAGATCA TGAAAGTCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0016235--C:aggresome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0035973--P:aggrephagy
GO:0000045--P:autophagosome assembly
GO:0097352--P:autophagosome maturation
GO:0071456--P:cellular response to hypoxia
GO:1901340--P:negative regulation of store-operated calcium channel activity
GO:0034140--P:negative regulation of toll-like receptor 3 signaling pathway
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:1902175--P:regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000864	Aegilops tauschii	49.65	9.00e-38	151.00
IUUC-Aml-001461	Ailuropoda melanoleuca	95.70	0.00e+00	806.00
IUUC-Atr-002470	Amborella trichopoda	39.93	1.00e-44	174.00
IUUC-Apl-003241	Anas platyrhynchos	83.58	0.00e+00	723.00
IUUC-Aca-004511	Anolis carolinensis	79.93	0.00e+00	723.00
IUUC-Aly-005419	Arabidopsis lyrata	37.59	1.00e-54	207.00
IUUC-Ath-007350	Arabidopsis thaliana	37.05	6.00e-54	205.00
IUUC-Ani-009418	Aspergillus nidulans	24.67	4.00e-09	55.80
IUUC-Bta-013048	Bos taurus	94.38	0.00e+00	828.00
IUUC-Bdi-014506	Brachypodium distachyon	35.71	8.00e-52	197.00
IUUC-Bol-015326	Brassica oleracea	34.92	3.00e-48	186.00
IUUC-Bra-018014	Brassica rapa	37.88	2.00e-41	163.00
IUUC-Cel-018631	Caenorhabditis elegans	38.48	1.00e-66	247.00
IUUC-Cja-019976	Callithrix jacchus	95.86	0.00e+00	836.00
IUUC-Cfa-020092	Canis familiaris	97.22	0.00e+00	840.00
IUUC-Cpo-022388	Cavia porcellus	93.89	0.00e+00	815.00
IUUC-Csa-024087	Chlorocebus sabaeus	96.82	0.00e+00	836.00
IUUC-Cho-024834	Choloepus hoffmanni	96.53	0.00e+00	838.00
IUUC-Cin-025136	Ciona intestinalis	50.74	4.00e-113	401.00
IUUC-Csv-026009	Ciona savignyi	52.15	5.00e-97	348.00
IUUC-Cne-026833	Cryptococcus neoformans	27.04	3.00e-13	69.30
IUUC-Cme-027155	Cyanidioschyzon merolae	58.10	1.00e-34	141.00
IUUC-Dor-030519	Dipodomys ordii	93.35	0.00e+00	800.00
IUUC-Dse-031421	Dothistroma septosporum	26.82	2.00e-13	70.10
IUUC-Dme-032013	Drosophila melanogaster	46.38	2.00e-111	396.00
IUUC-Ete-032273	Echinops telfairi	95.65	0.00e+00	813.00
IUUC-Eeu-034727	Erinaceus europaeus	76.52	1.00e-157	549.00
IUUC-Fca-036179	Felis catus	94.27	0.00e+00	791.00
IUUC-Fal-037642	Ficedula albicollis	83.09	0.00e+00	772.00
IUUC-Gga-041264	Gallus gallus	83.54	0.00e+00	804.00
IUUC-Gma-044112	Glycine max	50.96	7.00e-40	158.00
IUUC-Ggo-044969	Gorilla gorilla	96.85	0.00e+00	817.00
IUUC-Hsa-046669	Homo sapiens	96.67	0.00e+00	847.00
IUUC-Itr-048337	Ictidomys tridecemlineatus	95.31	0.00e+00	681.00
IUUC-Lch-050192	Latimeria chalumnae	75.87	0.00e+00	679.00
IUUC-Lpe-051401	Leersia perrieri	36.42	1.00e-36	147.00
IUUC-Loc-052846	Lepisosteus oculatus	76.33	0.00e+00	673.00
IUUC-Lma-053152	Leptosphaeria maculans	32.77	1.00e-11	64.30
IUUC-Laf-054278	Loxodonta africana	95.14	0.00e+00	799.00
IUUC-Mcc-055680	Macaca mulatta	96.85	0.00e+00	847.00
IUUC-Meu-056414	Macropus eugenii	79.13	7.00e-158	550.00
IUUC-Mtr-058674	Medicago truncatula	38.36	3.00e-41	162.00
IUUC-Mga-059894	Meleagris gallopavo	83.26	0.00e+00	641.00
IUUC-Mmr-061094	Microcebus murinus	96.67	0.00e+00	822.00
IUUC-Mdo-062728	Monodelphis domestica	88.28	0.00e+00	772.00
IUUC-Mmu-064088	Mus musculus	85.79	0.00e+00	842.00
IUUC-Mac-065458	Musa acuminata	34.49	4.00e-45	176.00
IUUC-Mpu-066282	Mustela putorius furo	92.61	0.00e+00	804.00
IUUC-Mlu-068158	Myotis lucifugus	95.93	0.00e+00	800.00
IUUC-Nle-069321	Nomascus leucogenys	96.48	0.00e+00	847.00
IUUC-Opr-071098	Ochotona princeps	87.35	4.00e-179	620.00
IUUC-Oan-072808	Ornithorhynchus anatinus	87.76	0.00e+00	748.00
IUUC-Ocu-074301	Oryctolagus cuniculus	86.16	0.00e+00	783.00
IUUC-Oba-074973	Oryza barthii	38.69	8.00e-43	167.00
IUUC-Obr-076444	Oryza brachyantha	49.66	5.00e-32	132.00
IUUC-Ogl-077319	Oryza glaberrima	33.97	7.00e-45	174.00
IUUC-Ogu-078074	Oryza glumaepatula	33.97	7.00e-45	174.00
IUUC-Oin-079142	Oryza indica	35.34	3.00e-44	172.00
IUUC-Olo-080565	Oryza longistaminata	34.29	2.00e-44	173.00
IUUC-Ome-081155	Oryza meridionalis	50.93	1.00e-33	137.00
IUUC-Oni-082272	Oryza nivara	35.34	3.00e-44	172.00
IUUC-Opu-083241	Oryza punctata	36.04	1.00e-50	194.00
IUUC-Oru-085257	Oryza rufipogon	35.34	3.00e-44	172.00
IUUC-Osa-086257	Oryza sativa	33.97	7.00e-45	174.00
IUUC-Ola-086802	Oryzias latipes	68.28	1.00e-135	476.00
IUUC-Olu-087597	Ostreococcus lucimarinus	32.85	9.00e-26	111.00
IUUC-Oga-088495	Otolemur garnettii	95.19	0.00e+00	798.00
IUUC-Oar-089711	Ovis aries	93.38	0.00e+00	796.00
IUUC-Ptr-091439	Pan troglodytes	96.30	0.00e+00	840.00
IUUC-Pan-092641	Papio anubis	96.85	0.00e+00	847.00
IUUC-Psi-093518	Pelodiscus sinensis	84.08	0.00e+00	724.00
IUUC-Pma-094727	Petromyzon marinus	42.66	2.00e-53	203.00
IUUC-Ppa-095193	Physcomitrella patens	52.80	2.00e-35	144.00
IUUC-Pfo-096638	Poecilia formosa	67.39	9.00e-170	590.00
IUUC-Pab-098699	Pongo abelii	92.59	0.00e+00	838.00
IUUC-Pop-099549	Populus trichocarpa	33.79	1.00e-49	190.00
IUUC-Pca-100497	Procavia capensis	83.81	2.00e-134	472.00
IUUC-Ppe-101901	Prunus persica	31.35	3.00e-60	226.00
IUUC-Pva-102513	Pteropus vampyrus	82.60	1.00e-145	509.00
IUUC-Pgr-103261	Puccinia graminis	54.76	2.00e-07	50.10
IUUC-Pte-104090	Pyrenophora teres	24.76	6.00e-06	45.40
IUUC-Rno-104908	Rattus norvegicus	85.79	0.00e+00	862.00
IUUC-Sce-106332	Saccharomyces cerevisiae	33.18	8.00e-15	74.30
IUUC-Sha-106881	Sarcophilus harrisii	83.77	0.00e+00	702.00
IUUC-Spo-108223	Schizosaccharomyces pombe	28.57	3.00e-12	66.20
IUUC-Smo-108910	Selaginella moellendorffii	36.49	4.00e-40	159.00
IUUC-Sit-110766	Setaria italica	38.61	2.00e-36	147.00
IUUC-Sly-111731	Solanum lycopersicum	37.97	6.00e-42	165.00
IUUC-Stu-112263	Solanum tuberosum	37.27	2.00e-40	160.00
IUUC-Sar-113648	Sorex araneus	90.61	0.00e+00	635.00
IUUC-Sbi-114307	Sorghum bicolor	38.21	6.00e-45	175.00
IUUC-Sre-115081	Sporisorium reilianum	24.17	7.00e-10	58.20
IUUC-Ssc-115820	Sus scrofa	97.78	0.00e+00	842.00
IUUC-Tgu-116845	Taeniopygia guttata	78.57	0.00e+00	685.00
IUUC-Tsy-119008	Tarsius syrichta	75.69	2.00e-155	542.00
IUUC-Tni-119780	Tetraodon nigroviridis	65.78	1.00e-168	585.00
IUUC-Tca-121558	Theobroma cacao	34.62	8.00e-53	201.00
IUUC-Tae-125419	Triticum aestivum	49.65	8.00e-38	151.00
IUUC-Tur-126248	Triticum urartu	48.95	1.00e-37	151.00
IUUC-Tme-127116	Tuber melanosporum	25.79	4.00e-09	55.80
IUUC-Tbe-127379	Tupaia belangeri	83.02	0.00e+00	670.00
IUUC-Ttr-128630	Tursiops truncatus	94.59	0.00e+00	848.00
IUUC-Uma-129639	Ustilago maydis	25.51	1.00e-09	57.80
IUUC-Vpa-130413	Vicugna pacos	71.71	6.00e-161	560.00
IUUC-Vvi-131599	Vitis vinifera	37.78	4.00e-41	162.00
IUUC-Xtr-132595	Xenopus tropicalis	79.70	0.00e+00	702.00
IUUC-Zma-135661	Zea mays	34.39	7.00e-45	174.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence