iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010677

Ensembl Protein ID

ENSAMXP00000026305.1

UniProt Accession

W5LT94; W5LT94_ASTMX

Genbank Protein ID

ENSAMXP00000026305

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01105173

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000025600.1	ENSAMXT00000026326.1	ENSAMXP00000026305.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.80e-13	50.4	497	543

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           ++l r+ p+SLqhL R aI++ ++++++    +LPLP++++d+L++++y+
   Q: 497  APLHRTFPFSLQHLARAAICSQTTYDGI---GALPLPPAMQDFLKEYHYK 543
           6778999*********************...****************985 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MEKVRKMWSN LRNRCHTLFH ANGSEANICS LDMDRLHCVV DVSQGPHGGE SQAARDSGAH 60
SQAPVVSGGR RSHNCVADIP QIVEITVDKE NEDVRKVPLV RRDSYSRHAP WGGKKKHSCS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAAAG TGAGGAAGAT GTGGAGCAAC CTCAGGAACA GATGTCACAC TCTCTTCCAC 60
GCTAACGGTT CAGAGGCCAA CATATGCAGC CTGGACATGG ATCGTCTCCA CTGTGTGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR022252--SOCS4/SOCS5_dom
IPR028420--SOCS5
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007259--P:JAK-STAT cascade
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000371	Aegilops tauschii	36.17	1.10e-01	29.60
IUUC-Aml-001789	Ailuropoda melanoleuca	72.82	3.00e-86	312.00
IUUC-Apl-003815	Anas platyrhynchos	63.76	0.00e+00	682.00
IUUC-Aca-004504	Anolis carolinensis	62.46	0.00e+00	636.00
IUUC-Bta-012338	Bos taurus	63.64	0.00e+00	673.00
IUUC-Cja-019828	Callithrix jacchus	63.05	0.00e+00	663.00
IUUC-Cfa-020369	Canis familiaris	62.94	0.00e+00	671.00
IUUC-Cpo-021397	Cavia porcellus	62.94	0.00e+00	681.00
IUUC-Csa-023856	Chlorocebus sabaeus	63.29	0.00e+00	674.00
IUUC-Cho-024700	Choloepus hoffmanni	49.78	2.00e-107	382.00
IUUC-Dre-028262	Danio rerio	81.33	0.00e+00	791.00
IUUC-Dno-029019	Dasypus novemcinctus	62.76	0.00e+00	681.00
IUUC-Dor-030273	Dipodomys ordii	72.82	2.00e-86	312.00
IUUC-Ete-032972	Echinops telfairi	52.79	3.00e-94	338.00
IUUC-Eca-033867	Equus caballus	63.29	0.00e+00	685.00
IUUC-Eeu-035208	Erinaceus europaeus	73.33	5.00e-87	314.00
IUUC-Fca-035806	Felis catus	63.51	0.00e+00	671.00
IUUC-Fal-037117	Ficedula albicollis	63.35	0.00e+00	679.00
IUUC-Gmo-039066	Gadus morhua	92.63	5.00e-121	428.00
IUUC-Gga-040876	Gallus gallus	63.41	0.00e+00	669.00
IUUC-Gac-042149	Gasterosteus aculeatus	73.94	0.00e+00	754.00
IUUC-Ggo-045169	Gorilla gorilla	62.17	0.00e+00	665.00
IUUC-Hsa-045805	Homo sapiens	63.29	0.00e+00	674.00
IUUC-Hvu-047122	Hordeum vulgare	41.67	2.20e-02	32.70
IUUC-Itr-049048	Ictidomys tridecemlineatus	63.46	0.00e+00	679.00
IUUC-Lch-049686	Latimeria chalumnae	63.83	0.00e+00	654.00
IUUC-Lpe-051639	Leersia perrieri	29.69	6.80e-01	28.90
IUUC-Loc-051745	Lepisosteus oculatus	70.00	0.00e+00	686.00
IUUC-Laf-054124	Loxodonta africana	63.81	0.00e+00	688.00
IUUC-Mcc-055175	Macaca mulatta	63.29	0.00e+00	674.00
IUUC-Meu-056557	Macropus eugenii	63.02	0.00e+00	680.00
IUUC-Mga-059214	Meleagris gallopavo	63.94	0.00e+00	676.00
IUUC-Mvi-060418	Microbotryum violaceum	30.86	1.70e-01	29.30
IUUC-Mmr-060613	Microcebus murinus	52.19	5.00e-139	487.00
IUUC-Mdo-062788	Monodelphis domestica	63.53	0.00e+00	664.00
IUUC-Mmu-064333	Mus musculus	63.40	0.00e+00	667.00
IUUC-Mpu-066048	Mustela putorius furo	63.29	0.00e+00	672.00
IUUC-Mlu-067430	Myotis lucifugus	62.59	0.00e+00	658.00
IUUC-Nle-069086	Nomascus leucogenys	63.46	0.00e+00	686.00
IUUC-Opr-070312	Ochotona princeps	64.51	0.00e+00	657.00
IUUC-Ont-072299	Oreochromis niloticus	77.11	0.00e+00	770.00
IUUC-Ocu-074123	Oryctolagus cuniculus	64.10	0.00e+00	659.00
IUUC-Ola-086934	Oryzias latipes	75.40	0.00e+00	782.00
IUUC-Oga-088535	Otolemur garnettii	63.46	0.00e+00	685.00
IUUC-Oar-089875	Ovis aries	63.75	0.00e+00	672.00
IUUC-Ptr-090541	Pan troglodytes	63.29	0.00e+00	674.00
IUUC-Pan-092416	Papio anubis	63.29	0.00e+00	674.00
IUUC-Psi-092960	Pelodiscus sinensis	63.86	0.00e+00	678.00
IUUC-Pma-094222	Petromyzon marinus	80.11	1.00e-85	310.00
IUUC-Pfo-096930	Poecilia formosa	73.38	0.00e+00	763.00
IUUC-Pab-098659	Pongo abelii	63.29	0.00e+00	674.00
IUUC-Pca-100222	Procavia capensis	63.57	0.00e+00	680.00
IUUC-Pva-102387	Pteropus vampyrus	62.28	0.00e+00	669.00
IUUC-Rno-105698	Rattus norvegicus	63.24	0.00e+00	669.00
IUUC-Sha-107234	Sarcophilus harrisii	62.89	0.00e+00	658.00
IUUC-Sar-113698	Sorex araneus	64.86	0.00e+00	627.00
IUUC-Ssc-115985	Sus scrofa	63.75	0.00e+00	683.00
IUUC-Tgu-116676	Taeniopygia guttata	63.94	0.00e+00	686.00
IUUC-Tru-118441	Takifugu rubripes	67.86	6.00e-179	620.00
IUUC-Tsy-119163	Tarsius syrichta	60.66	0.00e+00	634.00
IUUC-Tni-120436	Tetraodon nigroviridis	75.53	0.00e+00	766.00
IUUC-Tca-121131	Theobroma cacao	26.92	9.80e-01	27.70
IUUC-Tae-124846	Triticum aestivum	36.17	1.40e-01	29.30
IUUC-Tbe-127353	Tupaia belangeri	62.52	0.00e+00	668.00
IUUC-Ttr-128907	Tursiops truncatus	63.16	0.00e+00	661.00
IUUC-Vpa-130140	Vicugna pacos	63.35	0.00e+00	671.00
IUUC-Xtr-132817	Xenopus tropicalis	61.51	0.00e+00	665.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence