iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107234

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01031865

Gene Name

SOCS5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000009203.1	ENSSHAT00000010758.1	ENSSHAP00000010664.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	7.30e-16	57.9	478	523

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 5    wllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
            l r+ p+SLq++CR +I+rc++++++   d+LPLP++L+d+L++++y+
   Q: 478  SLNRTFPFSLQYICRAVICRCTTYDGI---DGLPLPSMLQDFLKEYHYK 523
           577899*********************...****************985 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MDKVGKMWNN FKYRCQNLFN HEGGNSSENI DVNSNKCLSV KERNISVGDL TPQQQSSPLR 60
ENVALQLELS PSKNSSRRNQ NCAADIPQIV EISIEKENDS CLTTTGTRLA RRDSYSRHAP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATAAAG TGGGGAAGAT GTGGAACAAC TTCAAATATA GGTGTCAGAA TCTTTTTAAC 60
CATGAAGGTG GAAACAGCAG TGAAAATATA GATGTGAACT CCAATAAATG TTTATCTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR022252--SOCS4/SOCS5_dom
IPR028420--SOCS5
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0071404--P:cellular response to low-density lipoprotein particle stimulus
GO:0019221--P:cytokine-mediated signaling pathway
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007259--P:JAK-STAT cascade
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0050728--P:negative regulation of inflammatory response
GO:0032715--P:negative regulation of interleukin-6 production
GO:0071638--P:negative regulation of monocyte chemotactic protein-1 production
GO:0045629--P:negative regulation of T-helper 2 cell differentiation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045627--P:positive regulation of T-helper 1 cell differentiation
GO:0016567--P:protein ubiquitination
GO:0097699--P:vascular endothelial cell response to fluid shear stress

KEGG

shr:100920946

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000371	Aegilops tauschii	34.69	1.90e-02	32.00
IUUC-Apl-003815	Anas platyrhynchos	90.17	0.00e+00	992.00
IUUC-Aca-004504	Anolis carolinensis	85.34	0.00e+00	865.00
IUUC-Ame-010677	Astyanax mexicanus	62.78	0.00e+00	638.00
IUUC-Bta-012338	Bos taurus	92.58	0.00e+00	994.00
IUUC-Cja-019828	Callithrix jacchus	92.02	0.00e+00	970.00
IUUC-Cfa-020369	Canis familiaris	91.65	0.00e+00	991.00
IUUC-Cpo-021397	Cavia porcellus	90.17	0.00e+00	1001.00
IUUC-Csa-023856	Chlorocebus sabaeus	92.21	0.00e+00	992.00
IUUC-Dre-028262	Danio rerio	62.98	1.00e-170	593.00
IUUC-Dno-029019	Dasypus novemcinctus	92.39	0.00e+00	1020.00
IUUC-Dme-031965	Drosophila melanogaster	67.44	2.00e-69	256.00
IUUC-Eca-033867	Equus caballus	91.28	0.00e+00	1004.00
IUUC-Fca-035806	Felis catus	92.02	0.00e+00	986.00
IUUC-Fal-037117	Ficedula albicollis	90.72	0.00e+00	983.00
IUUC-Gmo-039066	Gadus morhua	84.51	2.00e-107	382.00
IUUC-Gga-040876	Gallus gallus	89.98	0.00e+00	968.00
IUUC-Gac-042149	Gasterosteus aculeatus	67.10	0.00e+00	641.00
IUUC-Ggo-045169	Gorilla gorilla	91.09	0.00e+00	984.00
IUUC-Hsa-045805	Homo sapiens	92.21	0.00e+00	993.00
IUUC-Hvu-047122	Hordeum vulgare	34.15	1.10e-01	30.00
IUUC-Itr-049048	Ictidomys tridecemlineatus	90.72	0.00e+00	1004.00
IUUC-Lch-049686	Latimeria chalumnae	79.30	0.00e+00	838.00
IUUC-Lpe-051639	Leersia perrieri	32.31	2.90e-01	30.00
IUUC-Loc-051745	Lepisosteus oculatus	70.95	0.00e+00	713.00
IUUC-Lma-053042	Leptosphaeria maculans	24.17	2.50e-01	33.10
IUUC-Laf-054124	Loxodonta africana	90.72	0.00e+00	998.00
IUUC-Mcc-055175	Macaca mulatta	92.21	0.00e+00	992.00
IUUC-Meu-056557	Macropus eugenii	96.29	0.00e+00	1066.00
IUUC-Mga-059214	Meleagris gallopavo	89.80	0.00e+00	987.00
IUUC-Mmr-060613	Microcebus murinus	76.81	0.00e+00	770.00
IUUC-Mdo-062788	Monodelphis domestica	95.92	0.00e+00	1024.00
IUUC-Mmu-064333	Mus musculus	89.80	0.00e+00	968.00
IUUC-Mpu-066048	Mustela putorius furo	92.21	0.00e+00	991.00
IUUC-Mlu-067430	Myotis lucifugus	91.65	0.00e+00	965.00
IUUC-Nle-069086	Nomascus leucogenys	92.21	0.00e+00	1015.00
IUUC-Opr-070312	Ochotona princeps	88.68	0.00e+00	949.00
IUUC-Ont-072299	Oreochromis niloticus	64.90	0.00e+00	638.00
IUUC-Ocu-074123	Oryctolagus cuniculus	86.64	0.00e+00	930.00
IUUC-Ola-086934	Oryzias latipes	67.89	0.00e+00	664.00
IUUC-Oga-088535	Otolemur garnettii	92.21	0.00e+00	1018.00
IUUC-Oar-089875	Ovis aries	92.21	0.00e+00	993.00
IUUC-Ptr-090541	Pan troglodytes	92.21	0.00e+00	993.00
IUUC-Pan-092416	Papio anubis	92.21	0.00e+00	992.00
IUUC-Psi-092960	Pelodiscus sinensis	89.24	0.00e+00	984.00
IUUC-Pma-094222	Petromyzon marinus	52.56	3.00e-136	478.00
IUUC-Pfo-096930	Poecilia formosa	63.94	0.00e+00	657.00
IUUC-Pab-098659	Pongo abelii	92.21	0.00e+00	993.00
IUUC-Pca-100222	Procavia capensis	89.24	0.00e+00	987.00
IUUC-Pva-102387	Pteropus vampyrus	91.09	0.00e+00	981.00
IUUC-Rno-105698	Rattus norvegicus	90.35	0.00e+00	976.00
IUUC-Sar-113698	Sorex araneus	85.53	0.00e+00	879.00
IUUC-Ssc-115985	Sus scrofa	91.09	0.00e+00	1004.00
IUUC-Tgu-116676	Taeniopygia guttata	90.91	0.00e+00	989.00
IUUC-Tru-118441	Takifugu rubripes	59.41	9.00e-152	530.00
IUUC-Tsy-119163	Tarsius syrichta	85.90	0.00e+00	942.00
IUUC-Tni-120436	Tetraodon nigroviridis	66.79	0.00e+00	648.00
IUUC-Tca-121188	Theobroma cacao	31.43	8.80e-01	28.10
IUUC-Tae-124846	Triticum aestivum	34.69	3.60e-02	31.20
IUUC-Tbe-127353	Tupaia belangeri	91.65	0.00e+00	989.00
IUUC-Ttr-128907	Tursiops truncatus	92.21	0.00e+00	973.00
IUUC-Vpa-130140	Vicugna pacos	92.76	0.00e+00	998.00
IUUC-Xtr-132817	Xenopus tropicalis	78.33	0.00e+00	854.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence