iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027587

Ensembl Protein ID

ENSDARP00000129502.1

UniProt Accession

E7EXX1; E7EXX1_DANRE

Genbank Protein ID

ENSDARP00000079367

Protein Name

Mitogen-activated protein kinase kinase kinase 3

Genbank Nucleotide ID

BX324157

Gene Name

map3k3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000060348.6	ENSDART00000157028.1	ENSDARP00000129502.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UFD/PB1	77.42	0.00e+00	993.00	IUUC-Hsa-046137

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Danio rerio

Protein Sequence
(Fasta)

MNERQALHSI MKDLVALQMT RRQPTTTYDT AKTKPVIPAS SSNRLEDVRI KFEFCGERRI 60
LMFGRPVQFE EVQQKVKTFF GQQLDLHYMN NELSIPLRDQ DDLDKAIDLL DRSSNMKSIK 120

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Nucleotide Sequence
(Fasta)

TCACCTATAA TTGTTCACTT CAGCCTCCTA CGTCAGAACT GTGTGCGCGC CAGTGATGCT 60
GAGCGCGTAA CGTCACCAAG CGTGAACTGA AGAGAGGAGA AGCGCGCCCC CGAGCGTACA 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000270--PB1_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS

PROSITE

PS51745--PB1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM

Pfam

PF00564--PB1
PF00069--Pkinase

SMART

SM00666--PB1
SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004702--F:signal transducer, downstream of receptor, with serine/threonine kinase activity
GO:0030036--P:actin cytoskeleton organization
GO:0009948--P:anterior/posterior axis specification
GO:0007507--P:heart development

KEGG

dre:560211

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000356	Aegilops tauschii	48.46	8.00e-62	231.00
IUUC-Aml-001464	Ailuropoda melanoleuca	74.24	0.00e+00	978.00
IUUC-Ame-011807	Astyanax mexicanus	92.42	0.00e+00	1159.00
IUUC-Bta-012717	Bos taurus	77.23	0.00e+00	988.00
IUUC-Cja-019548	Callithrix jacchus	79.11	0.00e+00	927.00
IUUC-Cfa-020785	Canis familiaris	77.42	0.00e+00	994.00
IUUC-Cpo-021444	Cavia porcellus	77.39	0.00e+00	988.00
IUUC-Csa-023898	Chlorocebus sabaeus	74.28	0.00e+00	984.00
IUUC-Dno-028984	Dasypus novemcinctus	74.12	0.00e+00	975.00
IUUC-Eca-034089	Equus caballus	77.07	0.00e+00	990.00
IUUC-Fca-035656	Felis catus	77.54	0.00e+00	979.00
IUUC-Ggo-045339	Gorilla gorilla	74.28	0.00e+00	984.00
IUUC-Hsa-046137	Homo sapiens	77.42	0.00e+00	993.00
IUUC-Itr-048091	Ictidomys tridecemlineatus	77.23	0.00e+00	990.00
IUUC-Lpe-050706	Leersia perrieri	46.62	2.00e-69	256.00
IUUC-Loc-052751	Lepisosteus oculatus	84.02	0.00e+00	1119.00
IUUC-Laf-054342	Loxodonta africana	76.79	0.00e+00	976.00
IUUC-Mcc-055631	Macaca mulatta	74.28	0.00e+00	982.00
IUUC-Mga-059565	Meleagris gallopavo	74.68	0.00e+00	937.00
IUUC-Mmr-060745	Microcebus murinus	74.24	0.00e+00	983.00
IUUC-Mmu-063432	Mus musculus	76.95	0.00e+00	992.00
IUUC-Mpu-066544	Mustela putorius furo	74.81	0.00e+00	972.00
IUUC-Mlu-067655	Myotis lucifugus	76.63	0.00e+00	984.00
IUUC-Nle-070048	Nomascus leucogenys	71.80	0.00e+00	922.00
IUUC-Ont-071889	Oreochromis niloticus	89.68	0.00e+00	1164.00
IUUC-Oan-073137	Ornithorhynchus anatinus	64.21	3.00e-161	561.00
IUUC-Ola-087055	Oryzias latipes	82.32	0.00e+00	1067.00
IUUC-Oga-088913	Otolemur garnettii	74.01	0.00e+00	926.00
IUUC-Oar-090321	Ovis aries	74.54	0.00e+00	983.00
IUUC-Ptr-091046	Pan troglodytes	74.12	0.00e+00	981.00
IUUC-Pan-092280	Papio anubis	74.01	0.00e+00	979.00
IUUC-Pfo-096365	Poecilia formosa	88.05	0.00e+00	1145.00
IUUC-Pab-097785	Pongo abelii	74.28	0.00e+00	984.00
IUUC-Pva-102740	Pteropus vampyrus	74.20	0.00e+00	976.00
IUUC-Rno-104946	Rattus norvegicus	76.63	0.00e+00	991.00
IUUC-Ssc-115554	Sus scrofa	77.54	0.00e+00	973.00
IUUC-Tgu-117312	Taeniopygia guttata	78.47	0.00e+00	1001.00
IUUC-Tni-120426	Tetraodon nigroviridis	84.30	0.00e+00	1089.00
IUUC-Ttr-128646	Tursiops truncatus	74.28	0.00e+00	985.00
IUUC-Xtr-132121	Xenopus tropicalis	76.43	0.00e+00	960.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence