iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004598

Ensembl Protein ID

ENSACAP00000004720.2

UniProt Accession

G1KD82; G1KD82_ANOCA

Protein Name

Uncharacterized protein

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000004788.2	ENSACAT00000004827.2	ENSACAP00000004720.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	85.47	0.00e+00	817.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MLTGIIPLIK MMDTESQLCP LISLKEEDIG SPLSEDFLQD MESIKELSQS ISGDSSGALS 60
VTDFQSLENG PGSDGSIITD SLSPASSPSS VNLTTVPSSK DETSGTALNI ECRICGDKAS 120

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Nucleotide Sequence
(Fasta)

ACAGCTAATA AATGCTAACT GGCATAATTC CCCTCATCAA AATGATGGAC ACAGAAAGTC 60
AGCTTTGTCC CCTTATTTCC CTAAAAGAGG AGGACATTGG CAGTCCTTTA TCTGAAGATT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0070166--P:enamel mineralization
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

KEGG

acs:100567786

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002222	Ailuropoda melanoleuca	84.75	0.00e+00	820.00
IUUC-Apl-003330	Anas platyrhynchos	88.16	0.00e+00	825.00
IUUC-Acl-008339	Aspergillus clavatus	45.45	1.40e-01	29.30
IUUC-Ame-011508	Astyanax mexicanus	71.06	0.00e+00	665.00
IUUC-Bta-012621	Bos taurus	85.32	0.00e+00	813.00
IUUC-Cja-019688	Callithrix jacchus	85.47	0.00e+00	805.00
IUUC-Cfa-020859	Canis familiaris	84.62	0.00e+00	815.00
IUUC-Cpo-021607	Cavia porcellus	80.34	0.00e+00	758.00
IUUC-Csa-023313	Chlorocebus sabaeus	84.83	0.00e+00	797.00
IUUC-Cho-024741	Choloepus hoffmanni	75.00	0.00e+00	681.00
IUUC-Dre-027446	Danio rerio	69.79	0.00e+00	646.00
IUUC-Dno-029173	Dasypus novemcinctus	83.40	0.00e+00	777.00
IUUC-Dor-030581	Dipodomys ordii	82.66	0.00e+00	756.00
IUUC-Dme-031794	Drosophila melanogaster	35.93	4.00e-56	213.00
IUUC-Ete-032330	Echinops telfairi	82.05	0.00e+00	777.00
IUUC-Eca-033712	Equus caballus	85.32	0.00e+00	806.00
IUUC-Fca-036555	Felis catus	84.36	0.00e+00	813.00
IUUC-Fal-036677	Ficedula albicollis	89.53	0.00e+00	830.00
IUUC-Gmo-039240	Gadus morhua	80.53	0.00e+00	632.00
IUUC-Gga-040473	Gallus gallus	89.32	0.00e+00	833.00
IUUC-Gac-041872	Gasterosteus aculeatus	69.34	0.00e+00	662.00
IUUC-Ggo-045226	Gorilla gorilla	85.47	0.00e+00	805.00
IUUC-Hsa-046893	Homo sapiens	85.47	0.00e+00	805.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	83.12	0.00e+00	783.00
IUUC-Lch-050116	Latimeria chalumnae	78.42	0.00e+00	728.00
IUUC-Loc-052131	Lepisosteus oculatus	83.25	0.00e+00	668.00
IUUC-Laf-054323	Loxodonta africana	86.11	0.00e+00	813.00
IUUC-Mcc-054841	Macaca mulatta	85.11	0.00e+00	803.00
IUUC-Meu-056833	Macropus eugenii	76.50	0.00e+00	703.00
IUUC-Mga-059995	Meleagris gallopavo	80.51	0.00e+00	733.00
IUUC-Mdo-061954	Monodelphis domestica	85.87	0.00e+00	738.00
IUUC-Mmu-064295	Mus musculus	81.84	0.00e+00	759.00
IUUC-Mpu-066216	Mustela putorius furo	85.26	0.00e+00	817.00
IUUC-Nle-069970	Nomascus leucogenys	85.26	0.00e+00	803.00
IUUC-Ont-071594	Oreochromis niloticus	71.67	0.00e+00	663.00
IUUC-Oan-073501	Ornithorhynchus anatinus	88.02	0.00e+00	722.00
IUUC-Ocu-074634	Oryctolagus cuniculus	76.34	0.00e+00	753.00
IUUC-Oni-082926	Oryza nivara	28.30	1.20e-01	27.30
IUUC-Ola-086585	Oryzias latipes	78.31	0.00e+00	630.00
IUUC-Oga-088738	Otolemur garnettii	85.53	0.00e+00	810.00
IUUC-Oar-090453	Ovis aries	85.53	0.00e+00	814.00
IUUC-Ptr-091518	Pan troglodytes	85.26	0.00e+00	799.00
IUUC-Pan-092006	Papio anubis	85.26	0.00e+00	799.00
IUUC-Psi-093352	Pelodiscus sinensis	86.44	0.00e+00	819.00
IUUC-Pfo-096060	Poecilia formosa	71.67	0.00e+00	667.00
IUUC-Pab-098602	Pongo abelii	79.54	0.00e+00	707.00
IUUC-Pva-102175	Pteropus vampyrus	79.27	0.00e+00	753.00
IUUC-Rno-105283	Rattus norvegicus	82.48	0.00e+00	760.00
IUUC-Sce-106436	Saccharomyces cerevisiae	27.42	1.10e-01	28.10
IUUC-Sha-106560	Sarcophilus harrisii	85.93	0.00e+00	804.00
IUUC-Ssc-115266	Sus scrofa	84.40	0.00e+00	819.00
IUUC-Tgu-116778	Taeniopygia guttata	89.15	0.00e+00	828.00
IUUC-Tru-118436	Takifugu rubripes	70.61	0.00e+00	667.00
IUUC-Tsy-119642	Tarsius syrichta	93.51	6.00e-129	453.00
IUUC-Tni-119859	Tetraodon nigroviridis	70.46	0.00e+00	660.00
IUUC-Tvi-122624	Trichoderma virens	28.57	1.20e+00	25.40
IUUC-Tbe-127464	Tupaia belangeri	84.62	0.00e+00	806.00
IUUC-Ttr-129307	Tursiops truncatus	81.02	0.00e+00	754.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence