iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-091933

Ensembl Protein ID

ENSPANP00000015727.1

UniProt Accession

A0A096NRQ7; A0A096NRQ7_PAPAN

Genbank Protein ID

ENSPANP00000015727

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01090648

Gene Name

TRAF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000026161.1	ENSPANT00000028768.1	ENSPANP00000015727.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	98.20	0.00e+00	1020.00	IUUC-Hsa-046952

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Papio anubis

Protein Sequence
(Fasta)

MAAASVTPPG SLELLQPGFS KTLLGTKLEA KYLCSACGNV LRRPFQAQCG HRYCSFCLAS 60
ILSSGPQNCA ACVHEGIYEE GISILESSSA FPDNAARREV ESLPAVCPID GCTWKGTLKE 120

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Nucleotide Sequence
(Fasta)

GAAGGAGCCC ACGTGGGAAT CCCCTGAGCT GCGCCATGGC CAGAGTGAGT CACCCCTTTC 60
CAGCCAGCAA ATGAGGCGAG TCCCCAGGCC AAGGTGTCAC AGCTTCCAAG CTGGTGGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027133--TRAF2
IPR032070--TRAF_BIRC3-bd
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF16673--TRAF_BIRC3_bd
PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:1990597--C:AIP1-IRE1 complex
GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:0045121--C:membrane raft
GO:0097057--C:TRAF2-GSTP1 complex
GO:0000151--C:ubiquitin ligase complex
GO:0012506--C:vesicle membrane
GO:0046625--F:sphingolipid binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0043623--P:cellular protein complex assembly
GO:0071732--P:cellular response to nitric oxide
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:1903721--P:positive regulation of I-kappaB phosphorylation
GO:0032743--P:positive regulation of interleukin-2 production
GO:0043507--P:positive regulation of JUN kinase activity
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0002726--P:positive regulation of T cell cytokine production
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0097300--P:programmed necrotic cell death
GO:0051865--P:protein autoubiquitination
GO:0030163--P:protein catabolic process
GO:0070207--P:protein homotrimerization
GO:0070534--P:protein K63-linked ubiquitination
GO:0051023--P:regulation of immunoglobulin secretion
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002344	Ailuropoda melanoleuca	86.62	0.00e+00	905.00
IUUC-Apl-004202	Anas platyrhynchos	74.48	0.00e+00	827.00
IUUC-Aca-005029	Anolis carolinensis	59.16	2.00e-149	521.00
IUUC-Ame-011841	Astyanax mexicanus	55.48	0.00e+00	637.00
IUUC-Bta-013180	Bos taurus	86.35	0.00e+00	889.00
IUUC-Cja-019813	Callithrix jacchus	97.41	0.00e+00	1013.00
IUUC-Cfa-021205	Canis familiaris	91.02	0.00e+00	919.00
IUUC-Cpo-021346	Cavia porcellus	89.22	0.00e+00	921.00
IUUC-Csa-023809	Chlorocebus sabaeus	98.21	0.00e+00	912.00
IUUC-Dre-027669	Danio rerio	58.53	2.00e-177	615.00
IUUC-Dno-029458	Dasypus novemcinctus	83.75	0.00e+00	887.00
IUUC-Dor-030338	Dipodomys ordii	86.43	0.00e+00	829.00
IUUC-Eca-034401	Equus caballus	90.59	0.00e+00	946.00
IUUC-Eeu-034668	Erinaceus europaeus	71.01	6.00e-108	384.00
IUUC-Fca-036057	Felis catus	87.19	0.00e+00	929.00
IUUC-Fal-037560	Ficedula albicollis	72.83	0.00e+00	734.00
IUUC-Gmo-038964	Gadus morhua	62.82	0.00e+00	663.00
IUUC-Gga-040425	Gallus gallus	75.33	0.00e+00	825.00
IUUC-Gac-041908	Gasterosteus aculeatus	64.09	0.00e+00	679.00
IUUC-Ggo-044606	Gorilla gorilla	90.22	0.00e+00	926.00
IUUC-Hsa-046952	Homo sapiens	98.20	0.00e+00	1020.00
IUUC-Itr-049016	Ictidomys tridecemlineatus	76.64	0.00e+00	778.00
IUUC-Lch-049571	Latimeria chalumnae	58.97	0.00e+00	689.00
IUUC-Loc-051973	Lepisosteus oculatus	62.78	0.00e+00	631.00
IUUC-Laf-053815	Loxodonta africana	83.89	0.00e+00	851.00
IUUC-Mcc-054888	Macaca mulatta	99.40	0.00e+00	1036.00
IUUC-Meu-056547	Macropus eugenii	74.20	0.00e+00	665.00
IUUC-Mga-059819	Meleagris gallopavo	75.25	0.00e+00	783.00
IUUC-Mdo-062570	Monodelphis domestica	81.08	0.00e+00	851.00
IUUC-Mmu-063133	Mus musculus	87.23	0.00e+00	873.00
IUUC-Mpu-065802	Mustela putorius furo	87.89	0.00e+00	924.00
IUUC-Nle-070155	Nomascus leucogenys	98.60	0.00e+00	1024.00
IUUC-Opr-070856	Ochotona princeps	87.28	3.00e-115	408.00
IUUC-Ont-071930	Oreochromis niloticus	64.10	0.00e+00	707.00
IUUC-Ola-087397	Oryzias latipes	60.71	0.00e+00	683.00
IUUC-Oga-088109	Otolemur garnettii	94.41	0.00e+00	989.00
IUUC-Oar-090310	Ovis aries	76.86	0.00e+00	792.00
IUUC-Ptr-090643	Pan troglodytes	98.40	0.00e+00	1022.00
IUUC-Psi-093681	Pelodiscus sinensis	73.53	0.00e+00	781.00
IUUC-Pfo-096148	Poecilia formosa	60.34	0.00e+00	690.00
IUUC-Pab-098631	Pongo abelii	98.20	0.00e+00	1021.00
IUUC-Pca-100582	Procavia capensis	66.67	5.00e-89	321.00
IUUC-Pva-102396	Pteropus vampyrus	75.25	0.00e+00	741.00
IUUC-Rno-106120	Rattus norvegicus	86.83	0.00e+00	858.00
IUUC-Sha-106493	Sarcophilus harrisii	82.67	0.00e+00	874.00
IUUC-Sar-113570	Sorex araneus	93.92	2.00e-100	358.00
IUUC-Ssc-115843	Sus scrofa	85.38	0.00e+00	914.00
IUUC-Tgu-117144	Taeniopygia guttata	69.79	0.00e+00	704.00
IUUC-Tru-117853	Takifugu rubripes	61.95	0.00e+00	686.00
IUUC-Tni-120256	Tetraodon nigroviridis	65.07	0.00e+00	716.00
IUUC-Tbe-127943	Tupaia belangeri	66.33	2.00e-101	362.00
IUUC-Ttr-129246	Tursiops truncatus	89.29	0.00e+00	902.00
IUUC-Xtr-132279	Xenopus tropicalis	60.48	5.00e-173	600.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence