iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049649

Ensembl Protein ID

ENSLACP00000013463.1

UniProt Accession

H3AUZ2; H3AUZ2_LATCH

Genbank Protein ID

ENSLACP00000013463

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01083746

Gene Name

UBR2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000011851.1	ENSLACT00000013559.1	ENSLACP00000013463.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.50e-09	37.7	1116	1221
E3 activity/N-recognin/N-domain	4.60e-38	129.4	229	304
E3 activity/N-recognin/UBR-box	1.50e-30	105.8	97	167

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf......................kd......................gplvlpCgHvfhadClqkw.............. 29
           C++C+e+                       k+                      g+++++CgH++ha+C+q++              
   Q: 1116 CILCQEEQeikvdnkamvlaafvqrstvmsKNrskvihdsenfdpsyihpdlacGTHTGSCGHIMHAHCWQRYfdavqakeqrrqqr 1202
           888866554444433333333333333333003333333333333333333333899****************************** PP
   S: 30   ...pglknssskefrCPlC 45
              + +++++++ef+CPlC
   Q: 1203 lrvHTSYDVENGEFLCPLC 1221
           ******************* PP

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy++LfNDE+H+yeqviy+lqkA++++qkea++fat++d++GRr+v++Gd++ ce+ak +i++n +++++ pLkV++
   Q: 229  YYCMLFNDEVHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQFCEQAKAVIVRNNSRQTK-PLKVQI 304
           9*********************************************************************.****95 PP

E3 activity/N-recognin/UBR-box

   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCgrvfkvge +y+Cr+C+ d+t+vlC+eCf  +vH++H+y++++sggggfCdCGdteAw++g++C+k++
   Q: 97   HLCGRVFKVGEPTYSCRDCAFDPTCVLCMECFLGSVHREHRYRMTTSGGGGFCDCGDTEAWKKGPYCQKHE 167
           68*******************************************************************96 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MASDLELGIQ ALDSDLLECS AKDVALKWLQ ATDLPSDVYQ HLAFYVPKIY CRSPNPNPER 60
EDMLAQHVLL GPMEWYLAGE DPAIGFPKLE QANKPSHLCG RVFKVGEPTY SCRDCAFDPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTCCG ATTTAGAGCT TGGCATTCAG GCTCTTGACA GCGATTTACT GGAATGTTCC 60
GCCAAGGACG TCGCTCTGGT ATGGGTTAAG TCCATAAAGG AGATCTTAGG GCTATGACGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0008270--F:zinc ion binding
GO:0030163--P:protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000838	Aegilops tauschii	29.75	5.00e-23	103.00
IUUC-Aml-001876	Ailuropoda melanoleuca	68.30	0.00e+00	2157.00
IUUC-Apl-003828	Anas platyrhynchos	76.87	0.00e+00	2665.00
IUUC-Aca-005189	Anolis carolinensis	74.70	0.00e+00	2648.00
IUUC-Ago-007946	Ashbya gossypii	21.86	9.00e-27	116.00
IUUC-Ame-011917	Astyanax mexicanus	70.98	0.00e+00	2363.00
IUUC-Bta-012768	Bos taurus	74.43	0.00e+00	2607.00
IUUC-Cja-019797	Callithrix jacchus	71.89	0.00e+00	1954.00
IUUC-Cfa-020950	Canis familiaris	75.50	0.00e+00	2624.00
IUUC-Cpo-022385	Cavia porcellus	74.48	0.00e+00	2620.00
IUUC-Csa-024082	Chlorocebus sabaeus	74.99	0.00e+00	2625.00
IUUC-Cho-025029	Choloepus hoffmanni	78.74	0.00e+00	1296.00
IUUC-Cin-025148	Ciona intestinalis	35.60	2.00e-130	459.00
IUUC-Dre-028343	Danio rerio	70.26	0.00e+00	2379.00
IUUC-Dno-030002	Dasypus novemcinctus	68.59	0.00e+00	1425.00
IUUC-Dor-030207	Dipodomys ordii	62.77	0.00e+00	1210.00
IUUC-Ete-033162	Echinops telfairi	67.78	0.00e+00	1081.00
IUUC-Eca-033454	Equus caballus	74.66	0.00e+00	2603.00
IUUC-Eeu-034783	Erinaceus europaeus	58.18	0.00e+00	1100.00
IUUC-Fca-036588	Felis catus	74.96	0.00e+00	2603.00
IUUC-Fal-036919	Ficedula albicollis	75.72	0.00e+00	2583.00
IUUC-Ggr-040070	Gaeumannomyces graminis	22.41	7.00e-37	150.00
IUUC-Gga-041123	Gallus gallus	77.19	0.00e+00	2701.00
IUUC-Gac-042622	Gasterosteus aculeatus	63.11	0.00e+00	2050.00
IUUC-Ggo-045583	Gorilla gorilla	74.06	0.00e+00	2598.00
IUUC-Hsa-046343	Homo sapiens	75.27	0.00e+00	2630.00
IUUC-Hvu-047626	Hordeum vulgare	28.46	7.00e-23	103.00
IUUC-Lpe-051516	Leersia perrieri	26.05	4.00e-29	124.00
IUUC-Loc-052818	Lepisosteus oculatus	71.34	0.00e+00	2484.00
IUUC-Laf-054142	Loxodonta africana	75.01	0.00e+00	2619.00
IUUC-Mcc-055677	Macaca mulatta	74.70	0.00e+00	2612.00
IUUC-Meu-056204	Macropus eugenii	60.04	3.00e-144	506.00
IUUC-Mor-057051	Magnaporthe oryzae	22.05	3.00e-38	155.00
IUUC-Mpo-057372	Magnaporthe poae	24.62	6.00e-39	157.00
IUUC-Mtr-058538	Medicago truncatula	29.39	2.00e-22	102.00
IUUC-Mga-059698	Meleagris gallopavo	77.71	0.00e+00	2684.00
IUUC-Mmr-060901	Microcebus murinus	73.06	0.00e+00	2543.00
IUUC-Mdo-062014	Monodelphis domestica	76.17	0.00e+00	2660.00
IUUC-Mmu-063699	Mus musculus	73.63	0.00e+00	2556.00
IUUC-Mpu-066153	Mustela putorius furo	75.38	0.00e+00	2628.00
IUUC-Mlu-068151	Myotis lucifugus	74.26	0.00e+00	2567.00
IUUC-Ncr-068864	Neurospora crassa	21.66	4.00e-36	148.00
IUUC-Nle-069529	Nomascus leucogenys	74.93	0.00e+00	2623.00
IUUC-Opr-071107	Ochotona princeps	70.89	0.00e+00	1080.00
IUUC-Ont-072189	Oreochromis niloticus	62.58	0.00e+00	2013.00
IUUC-Oan-072893	Ornithorhynchus anatinus	76.23	0.00e+00	2665.00
IUUC-Ocu-074082	Oryctolagus cuniculus	74.55	0.00e+00	2596.00
IUUC-Ola-087460	Oryzias latipes	60.37	0.00e+00	2001.00
IUUC-Olu-087832	Ostreococcus lucimarinus	22.95	9.20e-01	29.30
IUUC-Oga-088432	Otolemur garnettii	74.77	0.00e+00	2629.00
IUUC-Oar-090206	Ovis aries	73.82	0.00e+00	2609.00
IUUC-Ptr-091180	Pan troglodytes	74.34	0.00e+00	2613.00
IUUC-Pan-092375	Papio anubis	74.93	0.00e+00	2620.00
IUUC-Psi-093049	Pelodiscus sinensis	76.58	0.00e+00	2662.00
IUUC-Pma-094152	Petromyzon marinus	46.00	6.00e-180	624.00
IUUC-Pfo-096524	Poecilia formosa	60.51	0.00e+00	1924.00
IUUC-Pab-097989	Pongo abelii	73.23	0.00e+00	2538.00
IUUC-Pca-100207	Procavia capensis	64.60	0.00e+00	1026.00
IUUC-Rno-105567	Rattus norvegicus	71.95	0.00e+00	2472.00
IUUC-Sce-106272	Saccharomyces cerevisiae	20.58	2.00e-21	99.40
IUUC-Sha-106980	Sarcophilus harrisii	76.48	0.00e+00	2564.00
IUUC-Sar-113332	Sorex araneus	67.84	0.00e+00	1682.00
IUUC-Ssc-115525	Sus scrofa	75.04	0.00e+00	2029.00
IUUC-Tgu-116943	Taeniopygia guttata	77.09	0.00e+00	2704.00
IUUC-Tru-117673	Takifugu rubripes	62.51	0.00e+00	2045.00
IUUC-Tsy-119032	Tarsius syrichta	73.52	0.00e+00	1446.00
IUUC-Tni-119987	Tetraodon nigroviridis	62.99	0.00e+00	2005.00
IUUC-Tae-125616	Triticum aestivum	33.90	2.00e-22	101.00
IUUC-Tur-126562	Triticum urartu	32.52	3.00e-22	101.00
IUUC-Tbe-128103	Tupaia belangeri	63.52	0.00e+00	867.00
IUUC-Ttr-128253	Tursiops truncatus	70.12	0.00e+00	2393.00
IUUC-Vpa-130540	Vicugna pacos	71.64	0.00e+00	2327.00
IUUC-Xtr-132690	Xenopus tropicalis	73.98	0.00e+00	2568.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence