iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000012173.1	ENSSHAT00000014358.1	ENSSHAP00000014240.1
ENSSHAG00000012173.1	ENSSHAT00000014359.1	ENSSHAP00000014241.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.80e-19	67.6	730	766
UBD/Beta-Prp	1.30e-43	149.5	515	873

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ +t l++ +d +++ s s+D  i  WD+ +g +
   Q: 730  GHSSYITHLDWsPDnKYIMSNSGDYEILYWDIPSGCK 766
           8***********998****************988865 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl.........................................lrslsgh 51
           ++k+h+ sv t  ++ +++ ll+ g++d+++++wd +                                               +++gh
   Q: 515  QIKAHDGSVFTLCQM-RNGMLLTGGGKDRKVILWDHDLNPEreievpeqygairavaegkadeflvgtsrnfilrgtfndgfQIEVQGH 602
           688999999996666.99999999999******99887555789999999999999999999999999999999999999966667999 PP
   S: 52   eaevtavkfspdgkilvtgseDrtikvw.dls........................................tgkcvhtlkghedsvls 99
           ++e + +  +p +++l+t+++Dr ++ w +++                                        t++ v++ +  ++++  
   Q: 603  TDELWGLATHPFKDLLLTCAQDRQVCMWnSVEhrlewtrlldepghcadfhpsgtvvaigthsgrwfvldaeTRDLVSIHTDGNEQLSV 691
           999*********99**************64448888999999999999999999999999999999999999***************** PP
   S: 100  lsfspsgdklvsGshdrtirvwdletgqclee...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvys 185
           +++s++g +l++Gshd+ i ++ +++    ++     +gh++ ++++ ++pd+++++s s D  +  Wd+++g+ l + ++ + +++ +
   Q: 692  MRYSKDGTFLAVGSHDNFIYLYVVSESGRKYSrygKCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPSGCKLIRNRS-DCKDIDW 779
           **********************998877776679999*********************************77777777766.6667777 PP
   S: 186  ls..........................fdsngkelvsgsldgtvklwdlq...tgecvrtlnghtdnvksvrfspnderlvsgs.sDg 244
           ++                           ++n+k ++ +++  +v l+++     +   +++ gh++ v+ v f+ nd++l+s++ +D 
   Q: 780  TTytcvlgfqvfgvwpegsdgtdinalvRSHNRKVIAVADDFCKVHLFQYPcskPKAPSHKYSGHSSHVTNVSFTHNDNHLISTGgKDM 868
           76666666555554444444433333325555455555555579999998876655669****************88888888776**9 PP
   S: 245  siriW 249
           si  W
   Q: 869  SIIQW 873
           99988 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MDGFAGSLDD SISATSTSDV QDRLSALELR VQQQEDEITV LKAALADVLR RLTISEDNVV 60
SVKKTASSKG HPGIREAISM SCISNGNGRS RKTNHGSSIS ISRKETFSSA AKSSTEKKKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNGCCC 60
AGCCCAGCCC GGCAGGACTC GAGCGAGTGG GGCAGGCTCA GCCGGGGCGC GCACGCCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0016020--C:membrane

KEGG

shr:100929628

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001465	Ailuropoda melanoleuca	86.90	0.00e+00	1714.00
IUUC-Apl-003728	Anas platyrhynchos	84.70	0.00e+00	1354.00
IUUC-Aca-004921	Anolis carolinensis	75.72	0.00e+00	1442.00
IUUC-Ame-011846	Astyanax mexicanus	80.41	0.00e+00	1436.00
IUUC-Bta-013457	Bos taurus	86.57	0.00e+00	1661.00
IUUC-Cja-019963	Callithrix jacchus	84.29	0.00e+00	1630.00
IUUC-Cfa-020344	Canis familiaris	87.64	0.00e+00	1693.00
IUUC-Cpo-022426	Cavia porcellus	87.11	0.00e+00	1654.00
IUUC-Csa-023822	Chlorocebus sabaeus	85.71	0.00e+00	1649.00
IUUC-Cho-024398	Choloepus hoffmanni	90.35	0.00e+00	700.00
IUUC-Dre-027697	Danio rerio	61.34	0.00e+00	968.00
IUUC-Dno-029822	Dasypus novemcinctus	86.35	0.00e+00	1634.00
IUUC-Ete-032548	Echinops telfairi	74.40	0.00e+00	1281.00
IUUC-Eca-033255	Equus caballus	86.91	0.00e+00	1726.00
IUUC-Fca-035637	Felis catus	87.37	0.00e+00	1724.00
IUUC-Fal-037030	Ficedula albicollis	83.43	0.00e+00	1586.00
IUUC-Gmo-038662	Gadus morhua	81.78	0.00e+00	1266.00
IUUC-Gga-041202	Gallus gallus	87.32	0.00e+00	1622.00
IUUC-Gac-041394	Gasterosteus aculeatus	72.97	0.00e+00	1334.00
IUUC-Ggo-044734	Gorilla gorilla	85.58	0.00e+00	1623.00
IUUC-Hsa-046616	Homo sapiens	86.39	0.00e+00	1674.00
IUUC-Lch-050585	Latimeria chalumnae	77.79	0.00e+00	1471.00
IUUC-Loc-052753	Lepisosteus oculatus	81.22	0.00e+00	1437.00
IUUC-Laf-054189	Loxodonta africana	83.74	0.00e+00	1614.00
IUUC-Mcc-055697	Macaca mulatta	86.83	0.00e+00	1677.00
IUUC-Mmr-060888	Microcebus murinus	85.82	0.00e+00	1612.00
IUUC-Mdo-062025	Monodelphis domestica	89.83	0.00e+00	1593.00
IUUC-Mmu-063591	Mus musculus	85.95	0.00e+00	1670.00
IUUC-Mpu-065718	Mustela putorius furo	87.64	0.00e+00	1723.00
IUUC-Mlu-068068	Myotis lucifugus	86.23	0.00e+00	1664.00
IUUC-Nle-069281	Nomascus leucogenys	85.08	0.00e+00	1579.00
IUUC-Opr-070938	Ochotona princeps	65.11	0.00e+00	1154.00
IUUC-Ont-071488	Oreochromis niloticus	72.88	0.00e+00	1305.00
IUUC-Oan-073561	Ornithorhynchus anatinus	72.77	0.00e+00	997.00
IUUC-Ocu-074399	Oryctolagus cuniculus	89.27	0.00e+00	1710.00
IUUC-Ola-086551	Oryzias latipes	71.55	0.00e+00	1287.00
IUUC-Oga-088783	Otolemur garnettii	87.93	0.00e+00	1714.00
IUUC-Oar-089716	Ovis aries	85.95	0.00e+00	1632.00
IUUC-Ptr-090942	Pan troglodytes	84.38	0.00e+00	1619.00
IUUC-Pan-091831	Papio anubis	86.82	0.00e+00	1680.00
IUUC-Psi-093094	Pelodiscus sinensis	87.07	0.00e+00	1662.00
IUUC-Pfo-097066	Poecilia formosa	69.88	0.00e+00	1271.00
IUUC-Pab-098351	Pongo abelii	85.82	0.00e+00	1625.00
IUUC-Pva-102783	Pteropus vampyrus	77.12	0.00e+00	1449.00
IUUC-Rno-105412	Rattus norvegicus	86.90	0.00e+00	1575.00
IUUC-Sar-113748	Sorex araneus	71.22	0.00e+00	1289.00
IUUC-Ssc-115740	Sus scrofa	85.63	0.00e+00	1633.00
IUUC-Tgu-116696	Taeniopygia guttata	84.84	0.00e+00	1541.00
IUUC-Tru-118506	Takifugu rubripes	72.02	0.00e+00	1309.00
IUUC-Tsy-119375	Tarsius syrichta	76.27	0.00e+00	1467.00
IUUC-Tni-120392	Tetraodon nigroviridis	68.81	0.00e+00	1190.00
IUUC-Tbe-127468	Tupaia belangeri	79.05	0.00e+00	1513.00
IUUC-Ttr-128746	Tursiops truncatus	82.48	0.00e+00	1682.00
IUUC-Vpa-130697	Vicugna pacos	85.73	0.00e+00	1662.00
IUUC-Xtr-132731	Xenopus tropicalis	78.55	0.00e+00	1540.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence