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Tag Content
UUCD2 ID IUUC-Ggo-044604
UUCD1 version UUC-GoG-00324
Ensembl Protein ID ENSGGOP00000007712.2
UniProt Accession G3QXZ2; G3QXZ2_GORGO
Protein Name Uncharacterized protein
Gene Name FBXW11
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSGGOG00000007880.2 ENSGGOT00000007919.2 ENSGGOP00000007712.2
ENSGGOG00000007880.2 ENSGGOT00000027322.1 ENSGGOP00000018003.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.80e-57 189.1 441 475
UBD/Beta-Prp 8.90e-69 232.3 354 519
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ v+c++f d +++vsG++Dg+ikvWDl    +
   Q: 441  GHEELVRCIRF-DnKRIVSGAYDGKIKVWDLQAALD 475
           8**********.44****************977665 PP
   

   UBD/Beta-Prp
   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
           +l r l gh a+v+ v+f+++  ++v++s Drtikvw+ st++ v+tl+gh++ + +l++      +vsGs+d+tir+wd+e g cl+ 
   Q: 354  TLRRVLVGHRAAVNVVDFDDK--YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLR- 437
           4556679*************9..8**************************************..************************. PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           +l+gh+++v+c++++   + +vsG++D+++++Wdl         ++  +lrtl + h ++v  l+fd+  ++++s s+d t+ +wd+
   Q: 438  VLEGHEELVRCIRFDN--KRIVSGAYDGKIKVWDLqaaldprapASTLCLRTLVE-HSGRVFRLQFDE--FQIISSSHDDTILIWDF 519
           ***************9..***********************************99.************..99**************7 PP
   
Organism Gorilla gorilla
Protein Sequence
(Fasta)
MEPDSVIEDK TIELMCSVPR SLWLGCANLV ESMCALSCLQ SMPSVRCLQI SNGTSSVIVS 60
RKRPSEGNYQ KEKDLCIKYF DQWSESDQVE FVEHLISRMC HYQHGHINSY LKPMLQRDFI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ggo-044604|E3,WD_repeat;UBD,Beta-Prp|Gorilla gorilla
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTAGTCGTGG CGCTCTCGAG GCCCTACCAT GAGCAAGCTC TTAACTCTTC AGGTCTGCAC 60
GTCCTACGTC CACAGTCCAG TGCTACTCTC AGCTCGAAGT TCAGCTTCGG GCTGCCAAGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ggo-044604|E3,WD_repeat;UBD,Beta-Prp|Gorilla gorilla
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR021977--Beta-TrCP_D
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12125--Beta-TrCP_D
PF12937--F-box-like
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM01028--Beta-TrCP_D
SM00256--FBOX
SM00320--WD40
Gene Ontology

GO:0005813--C:centrosome
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0042347--P:negative regulation of NF-kappaB import into nucleus
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0042753--P:positive regulation of circadian rhythm
GO:0045862--P:positive regulation of proteolysis
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006470--P:protein dephosphorylation
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001397 Ailuropoda melanoleuca 100.00 0.00e+00 1120.00
IUUC-Apl-003449 Anas platyrhynchos 94.76 0.00e+00 1068.00
IUUC-Ang-009766 Aspergillus niger 31.41 5.00e-52 199.00
IUUC-Ame-011174 Astyanax mexicanus 83.92 0.00e+00 983.00
IUUC-Bta-012920 Bos taurus 100.00 0.00e+00 1023.00
IUUC-Cja-018879 Callithrix jacchus 100.00 0.00e+00 1120.00
IUUC-Cfa-020021 Canis familiaris 100.00 0.00e+00 1120.00
IUUC-Cpo-022151 Cavia porcellus 99.60 0.00e+00 1014.00
IUUC-Csa-024095 Chlorocebus sabaeus 100.00 0.00e+00 1021.00
IUUC-Cho-024658 Choloepus hoffmanni 99.62 8.00e-156 543.00
IUUC-Dre-028160 Danio rerio 92.34 0.00e+00 953.00
IUUC-Dno-029485 Dasypus novemcinctus 88.96 0.00e+00 890.00
IUUC-Dor-030498 Dipodomys ordii 99.43 0.00e+00 1082.00
IUUC-Eca-033804 Equus caballus 100.00 0.00e+00 1036.00
IUUC-Fca-035887 Felis catus 94.29 0.00e+00 1038.00
IUUC-Fal-036783 Ficedula albicollis 95.48 0.00e+00 1038.00
IUUC-Gmo-038590 Gadus morhua 88.03 0.00e+00 974.00
IUUC-Gga-040628 Gallus gallus 95.10 0.00e+00 1033.00
IUUC-Gac-041305 Gasterosteus aculeatus 88.58 0.00e+00 992.00
IUUC-Hsa-046139 Homo sapiens 100.00 0.00e+00 1120.00
IUUC-Lch-050460 Latimeria chalumnae 97.17 0.00e+00 996.00
IUUC-Laf-053968 Loxodonta africana 96.27 0.00e+00 1108.00
IUUC-Mcc-055822 Macaca mulatta 91.58 0.00e+00 1063.00
IUUC-Mga-059225 Meleagris gallopavo 98.99 0.00e+00 1008.00
IUUC-Mvi-060284 Microbotryum violaceum 44.95 2.00e-69 257.00
IUUC-Mmr-060746 Microcebus murinus 100.00 0.00e+00 1120.00
IUUC-Mdo-062005 Monodelphis domestica 99.39 0.00e+00 1016.00
IUUC-Mmu-063851 Mus musculus 95.91 0.00e+00 1105.00
IUUC-Mpu-065716 Mustela putorius furo 100.00 0.00e+00 1022.00
IUUC-Mlu-067001 Myotis lucifugus 100.00 0.00e+00 1021.00
IUUC-Nle-069788 Nomascus leucogenys 93.73 0.00e+00 1033.00
IUUC-Opr-071229 Ochotona princeps 99.82 0.00e+00 1118.00
IUUC-Ont-071792 Oreochromis niloticus 89.57 0.00e+00 998.00
IUUC-Oan-072782 Ornithorhynchus anatinus 95.48 0.00e+00 1038.00
IUUC-Ocu-074894 Oryctolagus cuniculus 96.27 0.00e+00 1108.00
IUUC-Ola-086985 Oryzias latipes 85.87 0.00e+00 998.00
IUUC-Oga-088604 Otolemur garnettii 99.80 0.00e+00 1020.00
IUUC-Oar-090412 Ovis aries 96.05 0.00e+00 1043.00
IUUC-Ptr-091039 Pan troglodytes 99.82 0.00e+00 1118.00
IUUC-Pan-092770 Papio anubis 96.12 0.00e+00 1060.00
IUUC-Psi-093887 Pelodiscus sinensis 94.19 0.00e+00 1063.00
IUUC-Pno-094808 Phaeosphaeria nodorum 29.50 2.00e-45 177.00
IUUC-Pfo-096783 Poecilia formosa 86.22 0.00e+00 1002.00
IUUC-Pva-102547 Pteropus vampyrus 99.81 0.00e+00 1105.00
IUUC-Rno-105246 Rattus norvegicus 95.67 0.00e+00 1041.00
IUUC-Sha-107339 Sarcophilus harrisii 99.39 0.00e+00 1016.00
IUUC-Sja-107743 Schizosaccharomyces japonicus 35.38 5.00e-74 271.00
IUUC-Tgu-116541 Taeniopygia guttata 94.75 0.00e+00 1069.00
IUUC-Tru-117671 Takifugu rubripes 85.16 0.00e+00 989.00
IUUC-Tni-120359 Tetraodon nigroviridis 85.79 0.00e+00 939.00
IUUC-Tbe-127418 Tupaia belangeri 93.74 0.00e+00 1005.00
IUUC-Ttr-129131 Tursiops truncatus 100.00 0.00e+00 1119.00
IUUC-Vpa-130668 Vicugna pacos 99.63 0.00e+00 1107.00
IUUC-Xma-133187 Xiphophorus maculatus 95.36 1.00e-157 548.00
Created Date 25-Jun-2017

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